Dr. Charles Opondo[/caption]
Charles Opondo, BPharm MSc PhD.
Researcher in Statistics and Epidemiology
National Perinatal Epidemiology Unit
Nuffield Department of Population Health
University of Oxford
Oxford
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Our study measured fathers’ involvement in their child’s upbringing in infancy by looking at their emotional response to their child (e.g. feeling confident with the child, making a strong bond with the child), how involved they were in childcare (e.g. changing nappies, playing, night feeding, and also general care tasks around the house such as meal preparation) and their feelings of being a secure in their role as a parent (e.g. feeling included by mother in childcare, not feeling inexperienced with children).
We found that the children of fathers who scored highly in terms of their emotional response and feeling like a secure parent were less likely to have symptoms of behavioural problems when they were 9 or 11 years.
However, fathers being more involved in direct childcare did not seem to affect the child’s risk of having later behavioural problems.
Dr. Carlota Batres,[/caption]
Carlota Batres, Ph.D.
Perception Lab
School of Psychology and Neuroscience
University of St Andrews
UK
MedicalResearch.com: What is the background for this study?
Response: The background for this study is that previous research had found that people in different environments prefer different faces, which suggests that preferences change according to the environment. However, because previous research had never tracked the same participants across environmental changes, such a link could not be confirmed. Therefore, we sought to determine if, and to what extent, face preferences were malleable by repeatedly testing participants whose environment was not changing as well participants undergoing intensive training at an army camp.
Dr. Anita P. Barbee[/caption]
Anita P. Barbee, MSSW, Ph.D.
Professor and Distinguished University Scholar
President-Elect, International Association for Relationship Research
Kent School of Social Work
University of Louisville
Louisville, KY 40292
MedicalResearch.com: What is the background for this study?
Response: In 2010, our team at the University of Louisville with colleagues from Spalding University, were awarded a Tier 2 grant from the Office of Adolescent Health to study innovative teen pregnancy prevention interventions. We assembled a fantastic team of staff, students, community members and twenty three community based organizations to work together collaboratively to recruit and retain close to 1450 youth from the most distressed areas of our metropolitan area in order to conduct a randomized controlled trial.
We tested the efficacy of two interventions compared to a control condition. Our reason for this was to see how a new type of teen pregnancy intervention would perform compared to a more typical comprehensive sex education program, Reducing the Risk, which was already on the OAH list of evidence based interventions as well as to a control condition, which focused on community building but had no content on personal self esteem building, healthy relationships, dating violence or sexuality. The new program that was tested was Love Notes. Love Notes is a healthy relationship curriculum that addresses the context of sexual exploration as well as key points in preventing problematic outcomes of sexual activity such as the spread of disease, pregnancy and emotional heartache. The groups of youth that continue to have high rates of pregnancy tend to be disconnected from society through poverty and discrimination (minority and poor youth) or from family as a result of leaving home countries (refugees and immigrants), being removed from their homes due to child abuse or neglect (foster youth) or being rejected from families due to their LGBTQ orientations.
Dr. Lisa Harnack[/caption]
Lisa Harnack, DrPH, RD | Professor and Director
Nutrition Coordinating Center
Division of Epidemiology and Community Health
School of Public Health, University of Minnesota
Minneapolis, MN 55454-1087
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: There is interest in considering ways to reshape SNAP so that it better meets meet its objective to help families buy the food they need for good health. Prohibiting the purchase of foods such as soft drinks with SNAP benefits is one of the proposed program changes. Offering an incentive for the purchase of fruits and vegetables is another program change that is being discussed.
Little is known about the effects of prohibitions and restrictions on food purchasing and consumption. Consequently, we carried out an experimental trial to evaluate effects.
In our study we found that a food benefit program that includes both prohibitions on the purchase of less nutritious foods and incentives for purchasing nutritious foods may lead to a number of favorable changes in diet.
To elaborate, we found those enrolled in a food benefit program that prohibited the purchase of sugar sweetened beverages, sweet bakes goods, and candies with food program benefits and provided a 30% financial incentive for fruit and vegetable purchases had a number of favorable dietary changes that were significantly different from changes among those enrolled in a food benefit program that had neither prohibitions or incentives. These favorable changes included reduced consumption of calories, sugar sweetened beverages, sweet baked goods, and candies; and increased consumption of fruit. The overall nutritional quality of the diet also improved.
Fewer nutritional improvements were observed among those enrolled in food benefit programs that included prohibitions or incentives only.
Dr. Katherine Ahrens[/caption]
Dr. Katherine Ahrens PhD
Office of Population Affairs
Rockville, MD 20852
MedicalResearch.com: What is the background for this study?
Response: Lead exposure among children is linked to many adverse effects on health and cognitive development, which can be irreversible. The National Center for Health Statistics (NCHS) has linked 1999 to 2012 National Health and Nutrition Examination Survey (NHANES) data to administrative data for the Department of Housing and Urban Development’s (HUD) largest rental assistance programs (1999 through 2014), and these linked data allow calculation of the first-ever national blood lead level estimates among children living in HUD-assisted housing. Here we compare blood lead levels among children 1 to 5 years of age in 2005 to 2012 who received housing assistance during 1999 to 2014 with levels among children who did not receive housing assistance during that period.
Prof. Timothy Frayling[/caption]
Professor Timothy Frayling PhD
Professor of Human Genetics
University of Exeter Medical School
Exeter, UK
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: We know that genes and environmental factors influence our Body mass index. We know less about if and how they interact.
We wanted to answer the question of whether or not aspects of the environment and our lifestyles accentuate any genetic predisposition to obesity. The question is important as it may highlight aspects of the environment that cause some people to be particularly susceptible to gaining weight. Previous, separate, studies have suggested that specific aspects of the environment are to blame. These included sugary drinks, fried food and TV watching.
Dr. Kevin LaBar[/caption]
Kevin S. LaBar, Ph.D.
Professor and Head, Cognition & Cognitive Neuroscience Program
Co-Director of Undergraduate Studies in Neuroscience
Center for Cognitive Neuroscience
Duke University
Durham, NC
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Emotion research is limited by a lack of objective markers of emotional states. Most human research relies on self-report, but individuals may not have good insight into their own emotions. We have developed a new way to identify emotional states using brain imaging and machine learning tools. First, we induced emotional states using film and music clips while individuals were in an MRI scanner. We trained a computer algorithm to identify the brain areas that distinguished 7 emotions from each other (fear, anger, surprise, sadness, amusement, contentment, and a neutral state). This procedure created a brain map for each of the 7 emotions. Then, a new group of participants self-reported their emotional state every 30 seconds in an MRI scanner while no stimuli were presented. We could predict which emotion was spontaneously reported by the subjects by comparing their brain scans to each of the 7 emotion maps. Finally, in a large group of 499 subjects, we found that the presence of the fear map during rest predicted state and trait anxiety while the presence of the sadness map predicted state and trait depression.
Dr. Kai Ling Kong[/caption]
Kai Ling Kong, PhD, MS
Assistant Professor
Division of Behavioral Medicine
Department of Pediatrics
School of Medicine and Biomedical Sciences
State University of New York at Buffalo
MedicalResearch.com: What is the background for this study?
Response: Infant temperament, or individual behavior styles, can be reliably measured and is related to weight status. However, we know very little about the association of infants’ temperament and their motivation to eat versus engage in other activities (relative food reinforcement). Examining such associations is an important step given the need to use behavioral strategies in obesity prevention in early life. The purpose of our study was to determine if infant temperament, specifically the factors that have been linked with obesity risk, are associated with infant relative food reinforcement.
Dr. Luciano Costa[/caption]
Luciano J. Costa, MD, PhD
Associate Professor
Department of Medicine and UAB-CCC
Bone Marrow Transplantation and Cell Therapy Program
Birmingham, AL 35294
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Even though expected survival for multiple myeloma patients has increased over the last two decades, that improvement has not been much more pronounced among White than among patients of racial/ethnic minorities. It is possible that such discrepancy results from unequal access to care, particularly as treatment becomes more complex and expensive. We used a large dataset of patients with multiple myeloma to explore how socioeconomic factors, specifically marital status, income and insurance affect outcome and how these factors relate to race/ethnicity.
Dr. Tami Rowen[/caption]
Tami Rowen MD MS
Obstetrics, Gynecology and Reproductive Sciences
UCSF
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: This study sought to answer the question of which women are engaging in genital grooming and understand their motivations. Prior studies have been limited by geography and age thus our goal was to provide a nationally representative sample of women.
Ghenet Besera[/caption]
MedicalResearch.com Interview with:
Ghenet Besera, MPH
National Center for Chronic Disease Prevention and Health Promotion
CDC
MedicalResearch.com: What is the background for this study?
Response: The Title X program, established in 1970, offers confidential family planning and related preventive services to both men and women. While most clients are women, Title X also promotes use of services by men through delivery of male-focused services. Men’s family planning needs include services not only related to contraception, but also related to preconception care, infertility, and STD/ HIV services, which affect their reproductive health and overall health.
Dr. Kelli Komro[/caption]
Kelli A. Komro, MPH, PhD, Professor
Director of Graduate Studies
Behavioral Sciences and Health Education
Jointly Appointed, Epidemiology
Rollins School of Public Health
Emory University
Atlanta, GA 30322
MedicalResearch.com: What is the background for this study?
Dr. Komro: Epidemiologists have done a thorough job describing the income-health gradient, which shows a clear association between income and health. That is, as income increases, exposure to health risks and premature mortality decreases. Each step down on the income ladder decreases one’s health for many reasons related to material resources, physical environment exposures and social circumstances.
The income to health association begins at birth, and more than one in four women giving birth in the U.S. are below the poverty level, putting nearly 1 million babies at risk each year. Low-income mothers are more likely to give birth prematurely, to have low birth weight babies, and to suffer the death of their infant during the post-neonatal period (28 to 364 days old).
Given the importance of the income-health gradient, we set out to test the health effects of policies that are designed to increase economic security among low-income families. Our main question is: Do policies designed to reduce poverty and improve family economic security also improve health?
One relevant policy is minimum wage laws. A federal minimum wage was first enacted in 1938. The real value (in 2015 dollars) of the federal minimum wage reached a high of $10.85 in 1968. The current federal rate is $7.25. Many cities and states have passed minimum wage laws that are higher than the federal rate, and currently there is a range of minimum wage increases under active public and policymaker discussion.
Given that some states pass minimum wage standards and others do not, and that laws within states change over time, we took advantage of all the changes that have occurred to design a natural experiment. Our natural experiment examined the effects of state minimum wage laws on infant health.
MedicalResearch.com Interview with: [caption id="attachment_25021" align="alignleft" width="200"] Dr. Daniel Belsky[/caption] Daniel Belsky, PhD Assistant Professor of Medicine Duke University School of Medicine Durham, NC 27708 MedicalResearch.com: What is the background for this study? Dr. Belsky: The genome-wide association study (GWAS) of educational attainment by the Social Science Genetic Association Consortium was the first large-scale genetic investigation of a...
Dr Robb Rutledge[/caption]
MedicalResearch.com Interview with:
Dr Robb Rutledge
UCL Institute of Neurology and
Max Planck UCL Centre for Computational Psychiatry and Ageing Research
University College London
MedicalResearch.com: What is the background for this study? What are the main findings?
Dr. Rutledge: As we get older, dopamine levels in the brain gradually decline.
Dopamine has long been associated with risk taking and we have
recently found that it is related specifically to how willing people
are to take risks for potential rewards. It is widely believed that
older people are risk averse, but this is controversial, and it is
unknown whether age-related changes in dopamine are responsible for
changes in risk taking. In this study, we tested over 25,000 people
using a smartphone app called The Great Brain Experiment where players
tried to win as many points as they could by choosing between safe and
risky options. We found that older people were less willing to takes
risks for potential rewards than young people, the same situations
dopamine is known to be involved in.
Dr. Zhenmei Zhang[/caption]
Zhenmei Zhang, Ph.D.
Associate Professor
Department of Sociology
Michigan State University
East Lansing, MI48824
MedicalResearch.com: What is the background for this study?
Dr. Zhang: Blacks are especially hard hit by cognitive impairment and dementia. Recent estimates of dementia prevalence and incidence were substantially higher for blacks than whites. Reducing racial/ethnic disparities in dementia has been identified as a national priority by the National Alzheimer’s Project Act, which was signed into law by President Obama in 2011. So I really want to contribute to the ongoing discussion of the origins and pathways through which racial disparities in cognitive impairment is produced. If we have a better understanding of the factors contributing to racial disparities in cognitive impairment in later life, more effective interventions can be conducted to reduce the racial disparities.
Dr. Jill Cameron[/caption]
Jill Cameron, PhD
Canadian Institutes of Health Research New Investigator
Associate Professor,
Department of Occupational Science and Occupational Therapy
Rehabilitation Sciences Institute
Faculty of Medicine,
University of Toronto
MedicalResearch.com: What is the background for this study? What are the main findings?
Dr. Cameron: In the world of critical illness, a lot of research has focused on helping people to survive – and now that more people are surviving, we need to ask ourselves, what does quality of life and wellbeing look like afterwards for both patients and caregivers? The aim of our research was to identify factors associated with family caregiver health and wellbeing during the first year after patients were discharged from the Intensive Care Unit. We examined factors related to the patient and their functional wellbeing, the caregiving situation including the impact it has on caregivers everyday lives, and caregiver including their sense of control over their lives and available social support. We used Pearlin’s Caregiving Stress Process model to guide this research.
From 2007-2014, caregivers of patients who received seven or more days of mechanical ventilation in an ICU across 10 Canadian university-affiliated hospitals were given self-administered questionnaires to assess caregiver and patient characteristics, caregiver depression symptoms, psychological wellbeing, and health-related quality of life. Assessments occurred seven days and three, six and 12-months after ICU discharge.
The study found that most caregivers reported high levels of depression symptoms, which commonly persisted up to one year and did not improve in some. Caregiver sense of control, impact on caregivers’ everyday lives, and social support had the largest relationships with the outcomes. Caregivers’ experienced better health outcomes when they were older, caring for a spouse, had higher income, better social support, sense of control, and caregiving had less of a negative impact on their everyday lives. No patient characteristics or indicators of illness severity were associated with caregiver outcomes.
Poor caregiver outcomes may compromise patients’ rehabilitation potential and sustainability of home care. Identifying risk factors for caregiver distress is an important first step to prevent more suffering and allow ICU survivors and caregivers to regain active and fulfilling lives.
Dr. Tyler VanderWeele[/caption]
Dr. Tyler VanderWeele PhD
Professor of Epidemiology
Department of Epidemiology
Department of Biostatistics
Harvard T. H. Chan
School of Public Health
MedicalResearch.com: What is the background for this study? What are the main findings?
Dr. VanderWeele: There have been some prior studies on religious service attendance and mortality. Many of these have been criticized for poor methodology including the possibility of reverse causation – that only those who are healthy can attend services, so that attendance isn’t necessarily influencing health. We tried to address some of these criticisms with better methodology. We used repeated measures of attendance and health over time to address this, and a very large sample, and controlled for an extensive range of common causes of religious service attendance and health. This was arguably the strongest study on the topic to date and addressed many of the methodological critiques of prior literature. We found that compared with women who never attended religious services, women who attended more than once per week had 33% lower mortality risk during the study period. Those who attended weekly had 26% lower risk and those who attended less than once a week had 13% lower risk.
Dr. Erica Spatz[/caption]
Erica Spatz, MD, MHS
Assistant Professor, Section of Cardiovascular Medicine
Center for Outcomes Research and Evaluation
Yale University School of Medicine/Yale-New Haven Hospital
New Haven, CT 06520
MedicalResearch.com: What is the background for this study? What are the main findings?
Dr. Spatz: Rates of heart attack have declined during the last 15 years. But whether communities of different economic status or in different geographic regions experienced similar declines is unknown, especially as efforts to prevent cardiovascular disease and manage heart attacks may not have been equally successful in communities with different resource capacity.
Our study shows that trends in the incidence of and mortality from heart attack were similar in low, average and high income communities. However, low-income communities had higher hospitalization rates than average and high income communities throughout the 15 year study period. Interestingly mortality rates were similar.
Dr. Joan Luby[/caption]
Joan L. Luby, MD Samuel and Mae S. Ludwig Professor of Child Psychiatry Director, Early Emotional Development Program Washington University School of Medicine St. Louis, Missouri
MedicalResearch.com: What is the background for this study? What are the main findings? Dr. Luby: The study was designed to investigate brain development in early onset mental disorders. The main findings validate depression in preschoolers with brain change evident this young similar to that known in adults. We also found effects of maternal support on brain development in this process which is what the current paper focuses on .
Nicole Valtorta[/caption]
Nicole Valtorta
NIHR Doctoral Research Fellow
Department of Health Sciences
University of York, UK
Medical Research: What is the background for this study? What are the main findings?
Response: Lonely and socially isolated adults are at increased risk of mortality. The influence of social relationships on morbidity is widely accepted, but the size of the risk to cardiovascular health is unclear. We systematically reviewed the evidence from prospective cohort studies to investigate the association between loneliness or social isolation and incident coronary heart disease (CHD) and stroke. We identified 23 papers reporting data from 16 longitudinal datasets, for a total of 4,628 CHD and 3,002 stroke events. Reports of eleven studies (CHD) and eight studies (stroke) provided data suitable for meta-analyses, the results of which indicated that deficiencies in social relationships are associated with an increased risk of developing CHD and stroke. People who were lonely or isolated had, on average, a 29% greater risk of incident CHD; similarly, the risk of developing stroke was 32% greater among isolated individuals.
Dr. Paula Braitstein[/caption]
Paula Braitstein, PhD
Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
Department of Medicine, College of Health Sciences, School of Medicine, Moi University, Eldoret, Kenya Department of Epidemiology, Fairbanks School of Public Health, Indiana University, Indianapolis
Regenstrief Institute Inc, Indianapolis, Indiana
MedicalResearch.com: What is the background for this study?
Dr. Braitstein: There are vast numbers of children and youth in the world who find themselves in street circumstances. Yet, there is an absence of consensus among academics, policymakers, stakeholders, and international organizations regarding the causes of child and youth street-involvement around the world. Without data concerning these reasons, policies are developed or implemented to mitigate street-involvement without taking these causes into account. Often, the prevailing paradigm assumes that children and youth on the street are juvenile delinquents and the government response is often characterized by social exclusion, criminalization, and oppression by police and civic authorities. Therefore we wanted to find out what reasons do children and youth self-report for their street-involvement globally.
MedicalResearch.com: What are the main findings?
Dr. Braitstein: We systematically reviewed the literature and compiled data from 49 studies representing 24 countries globally. Street-connected children and youth most frequently reported poverty, family conflict, and abuse as their reasons for street-involvement. They infrequently identified delinquent behaviours for their circumstances. There were no significant differences between males and females reported reasons, with the exception of females in developed regions who were more likely to report abuse.
Dr.Dayu Lin[/caption]
Dr. Dayu Lin, PhD
NYU Langone Medical Center
MedicalResearch.com: What is the background for this study? What are the main findings?
Dr. Lin: Decades of researchs including those from our labs have identified some key sites for aggressive actions, but the neural substrates of aggressive intention remain unclear. In this study, we designed a task to evaluate the aggressive intention of the mice in the absence of aggression provoking cues (another male mouse) and identified a small hypothalamic area, namely the ventrolateral part of the ventromedial hypothalamus, as a key brain region for aggressive motivation.