Author Interviews, JAMA, Weight Research / 25.02.2014

MedicalResearch.com Interview with: Cynthia L. Ogden, PhD, MRP Epidemiologist and Analysis Branch Chief NHANES Program/NCHS/CDC Hyattsville, MD 20782 MedicalResearch.com: What are the main findings of the study? Dr. Ogden: We continue to track obesity levels in the US population using data from the National Health and Nutrition Examination Survey. New data are now available for 2011-2012. We found that 17% of youth and 35% of adults were obese.  Overall there has been no change in obesity levels among either youth or adults in the last 10 years. The prevalence of obesity among youth was 16.9% - exactly the same as in 2009-2010.  In separate age groups analyses we found a decrease in obesity among 2-5 year olds and an increase in obesity among older women 60+ years. (more…)
Author Interviews, PLoS, Weight Research / 25.02.2014

Nir Y. Krakauer Ph.D Assistant Professor Department of Civil Engineering The City College of New York New York, New YorkMedicalResearch.com Interview with: Nir Y. Krakauer Ph.D Assistant Professor Department of Civil Engineering The City College of New York New York, New York MedicalResearch.com: What are the main findings of the study? Dr. Krakauer: We studied the association between the recently proposed body shape index (ABSI) -- which combines waist circumference, height and weight measurements -- and risk of death in a United Kingdom population sample. We found that high ABSI predicted greater mortality hazard, with death rates increasing by about 13% per standard deviation increase in ABSI. Further, ABSI was a stronger predictor of early death than BMI, waist circumference, or other indices based on waist circumference such as waist to height ratio and waist to hip ratio. For a given starting ABSI value, reducing A Body Shape Index over a 7-year period was associated with lowered mortality risk, . (more…)
Author Interviews, Genetic Research, JAMA, Weight Research / 18.02.2014

Dr Clare Llewellyn PhD Cpsychol Lecturer in Behavioural Obesity Research Health Behaviour Research Centre Department of Epidemiology and Public Health University College London, LondonMedicalResearch.com Interview with: Dr Clare Llewellyn PhD Cpsychol Lecturer in Behavioural Obesity Research Health Behaviour Research Centre Department of Epidemiology and Public Health University College London, London  MedicalResearch.com: What are the main findings of the study? Dr. Llewellyn:This study indicated that appetite – and, in particular, satiety sensitivity (how quickly you feel full during eating, or how long you remain full after eating) – could be one of the mechanisms through which ‘obesity genes’ influence body weight. We know that body weight has a strong genetic basis, but the mechanisms through which ‘obesity genes’ influence weight are largely unknown. We showed that children with a higher genetic predisposition to obesity (estimated from a score comprising 28 known obesity-related genes) not only had more body fat (a larger BMI and waist circumference), but importantly they were also less sensitive to satiety. (more…)
Author Interviews, Diabetes, PLoS, Weight Research / 14.02.2014

Dorte Vistisen Senior researcher, MSc PhD 469 - Epidemiology DK-2820 Gentofte DenmarkMedicalResearch.com Interview with: Dorte Vistisen Senior researcher, MSc PhD 469 - Epidemiology DK-2820 Gentofte Denmark MedicalResearch.com: What are the main findings of the study? Dr. Vistisen: Our study highlights the complexity of type 2 diabetes. We show that in most people the development of type 2 diabetes is preceded by many years of overweight and not by massive weight gain. (more…)
Author Interviews, Colon Cancer, General Medicine, PLoS, University of Michigan, Weight Research / 09.02.2014

Jenifer I Fenton Assistant Professor Department of Food Science and Human Nutrition Michigan State University East Lansing, MI 48824MedicalResearch.com Interview with: Jenifer I Fenton Assistant Professor Department of Food Science and Human Nutrition Michigan State University East Lansing, MI 48824 MedicalResearch.com: What are the main findings of the study? Dr. Fenton: This was a cross-sectional study, and thus, a snapshot in time. Although it cannot infer cause or temporality of obesity and colon polyp risk in men, it does show that obese men were more likely to have a polyp than their lean counterpart. In addition, there were serum biomarkers also associated with this risk. This could eventually lead to future blood tests to identify individuals at greater risk for polyps and inform screening recommendations. (more…)
Author Interviews, Depression, Diabetes, Diabetologia, Weight Research / 07.02.2014

Dr Peter de Jonge Interdisciplinary Center for Psychopathology and Emotion Regulation, University Medical Center Groningen, University of Groningen, NetherlandsMedicalResearch.com Interview with: Dr Peter de Jonge Interdisciplinary Center for Psychopathology and Emotion Regulation, University Medical Center Groningen, University of Groningen, Netherlands MedicalResearch.com: What are the main findings of the study? Dr. de Jonge: The main findings were that depression and impulse control disorders, in particular binge eating and bulimia were associated with diabetes. (more…)
Author Interviews, Lancet, Weight Research / 28.01.2014

Professor Sally Wyke Deputy Director, Institute of Health and Wellbeing Professor (Institute of Health and Wellbeing Social Sciences) The University of GlasgowMedicalResearch.com Interview with: Professor Sally Wyke Deputy Director, Institute of Health and Wellbeing Professor (Institute of Health and Wellbeing Social Sciences) The University of Glasgow MedicalResearch.com: What are the main findings of the study? Prof. Wyke: The FFIT programme was very effective.  The men who did the programme lost nine times as much weight as the men who did not.  On average, they lost over 5.5kg  (11lbs)and kept it off for the full 12 months. In addition, we found highly significant differences in favour of the intervention objectively-measured waist, percentage body-fat, systolic and diastolic blood pressure, and self-reported physical activity, diet and indicators of well-being and physical aspects of quality of life. (more…)
Author Interviews, Sleep Disorders, University of Pittsburgh, Weight Research / 06.12.2013

Dr G. Neil Thomas, 
Regional Director, NIHR Research Design Service West Midlands 
 Deputy Director, Master of Public Heath Programme 
Reader in Epidemiology Department of Public Health, Epidemiology and Biostatistics
 School of Health and Population Sciences
 College of Medical and Dental Sciences The University of Birmingham
 Edgbaston, Birmingham, B15 2TTMedicalResearch.com Interview with: Dr G. Neil Thomas, 
Regional Director, NIHR Research Design Service West Midlands Deputy Director, Master of Public Heath Programme 
Reader in Epidemiology Department of Public Health, Epidemiology and Biostatistics
 School of Health and Population Sciences
 College of Medical and Dental Sciences The University of Birmingham
 Edgbaston, Birmingham, B15 2TT MedicalResearch.com: What are the main findings of the study? Dr. Thomas: This population of severely obese individuals (mean BMI 47kg/m2) from a regional specialist weight management service poor sleep quality (Pittsburgh Sleep Quality Index, PSQI) and daytime sleepiness (Epworth Sleepiness Scale) were strongly associated with poorer quality of life (Impact of Quality of Life-Lite (IWQOL-Lite) (more…)
Author Interviews, Diabetes, Weight Research / 25.11.2013

Ira Tabas, M.D., Ph.D. Richard J. Stock Professor and Vice-Chair of Research Department of Medicine Professor of Anatomy & Cell Biology (in Physiology and Cellular Biophysics) Columbia University New York, NY 10032MedicalResearch.com Interview with: Ira Tabas, M.D., Ph.D. Richard J. Stock Professor and Vice-Chair of Research Department of Medicine Professor of Anatomy & Cell Biology  (in Physiology and Cellular Biophysics) Columbia University New York, NY 10032 MedicalResearch.com: What are the main findings of the study?  Dr. Tabas: We discovered a new pathway in the liver, relevant to humans, that controls the two hallmarks of type 2 diabetes (T2D), namely, excessive glucose production and defective insulin signaling.  Thus, if drugs could be developed to inhibit this pathway, they could be very effective at treating or preventing T2D. (more…)
Author Interviews, Diabetes, Heart Disease, JCEM, Weight Research / 21.11.2013

Carlos Lorenzo, MD Department of Medicine, University of Texas Health Science Center 7703 Floyd Curl Drive San Antonio, Texas 78229MedicalResearch.com Interview with: Carlos Lorenzo, MD Department of Medicine, University of Texas Health Science Center 7703 Floyd Curl Drive San Antonio, Texas 78229 MedicalResearch.com: What are the main findings of the study? Dr. Lorenzo: Metabolically healthy obese individuals are at increased risk of developing of diabetes and cardiovascular disease. These findings were demonstrated in men and women and in Mexican Americans and non-Hispanic whites. Management of excess weight and any metabolic abnormality appears to be important for all individuals. Our study is also in agreement with previous studies that indicate that metabolically unhealthy normal weight individuals are at increased risk of developing of diabetes and cardiovascular disease. (more…)
Author Interviews, Heart Disease, JAMA, Weight Research / 21.11.2013

MedicalResearch.com Interview with: Prof. Prashanthan SandersMedicalResearch.com Interview with: Prof. Prashanthan Sanders Director, Centre for Heart Rhythm Disorders University of Adelaide | Royal Adelaide Hospital | SAHMRI NHMRC Practitioner Fellow Centre for Heart Rhythm Disorders Department of Cardiology | Royal Adelaide Hospital Adelaide 5000 | Australia MedicalResearch.com: What are the main findings of the study? Answer: Aggressive treatment of risk factors and weight reduced the symptom burden associated with atrial fibrillation. It is therefore important that in a similar manner to how we treat coronary artery disease, in atrial fibrillation there should be management directed at the reasons why these individuals got AF in the first place. (more…)
Author Interviews, Diabetes, Weight Research / 19.11.2013

Alison E. Field, ScD Associate Professor of Pediatrics Boston Children's Hospital Division of Adolescent Medicine Boston, MA 02115MedicalResearch.com Interview with: Alison E. Field, ScD Associate Professor of Pediatrics Boston Children's Hospital Division of Adolescent Medicine Boston, MA  02115 MedicalResearch.com: What are the main findings of the study?
 Answer: Girls who engage in frequent binge eating are much more likely than their peers with the same BMI to develop diabetes. The risk was greatest among girls with binge eating disorder. (more…)
Author Interviews, PLoS, Weight Research / 16.11.2013

MedicalResearch.com Interview with: Guang Sun MD, PhD Professor, Discipline of medicine Faculty of medicine, Memorial University Canada MedicalResearch.com:  What are the main findings of the study? Dr. Sun: Plenty of anecdotal reports on how ‘Food Addiction’ may be a potential culprit of the rising prevalence of obesity. However to date no scientific study, based on a comprehensive criterion of the diagnosis of Food Addiction, has been performed at the population level. The main findings are in the following fours aspects: 1)         Food Addiction is indeed an important contributing factor in the development of obesity. 2)         The prevalence of Food Addition was 5.4% and increased concomitantly with obesity status defined by either body mass index (BMI) or body fat percentage (%BF). In another word, there is one food addict in every twenty adults (Newfoundland Province, Canada) 3)         Clinical Symptom Count(s) of Food Addiction is strongly associated with the severity of obesity. 4)         Women are twice as likely to be diagnosed with “Food Addiction” than men. (more…)
Author Interviews, Karolinski Institute, OBGYNE, Weight Research / 16.11.2013

MedicalResearch.com: Interview with: Olof Stephansson MD, PhD Associate professor, senior consultant in obstetrics and gynaecologyDepartment of Medicine, Clinical Epidemiology Unit, Karolinska InstitutetDepartment of Women’s and Children’s Health, Division of Obstetrics and Gynaecology Karolinska Institutet, Stockholm, Sweden MedicalResearch.com: What are the main findings of the study? Answer: Women with a history of bariatric surgery have an increased risk of preterm delivery, a doubled risk for small-for-gestational-age births and a reduction in large-for-gestational-age births. Also when considering maternal weight, education, age, parity and year of birth. There was no increased for stillbirth or neonatal mortality. (more…)
Author Interviews, Metabolic Syndrome, Obstructive Sleep Apnea, Weight Research / 15.11.2013

MedicalResearch.com Interview with: MedicalResearch.com Interview with: Dr. Emilia Mazzuca Biomedical Department of Internal and Specialistic Medicine (DIBIMIS) Section of Pneumology and Dr. Maria R Bonsignore, MD Associate Professor in Respiratory Medicine University of Palermo, Palermo, Italy MedicalResearch.com: What are the main findings of the study? Answer: Our main goal was to investigate gender-related interactions between obstructive sleep apnea (OSA) and obesity while taking associated metabolic abnormalities into account. We analyzed 423 men and 105 women previously studied for the association of OSA and the Metabolic Syndrome (MetS) (Bonsignore et al, Eur Respir J, 2012), to assess whether markers of general and visceral obesity were differently associated with OSA in men and women. Multivariate analysis showed that in men the apnea-hypopnea index (AHI), an indicator of OSA severity, was associated with waist circumference, a marker of visceral obesity, and body mass index (BMI); conversely, in women AHI was associated with hip circumference, a marker of subcutaneous fat deposition, and neck size.  The results were similar when patients without a diagnosis of MetS were analyzed; conversely, in patients with MetS, waist circumference was the only significant marker of OSA in both genders. (more…)
Author Interviews, Chocolate, Nature, Nutrition, Pediatrics, Weight Research / 12.11.2013

Magdalena Cuenca García, PhD University of Granada Department of Physiology, School of Medicine Avd. Madrid 12; 18012 Granada (Spain)MedicalResearch.com Interview with: Magdalena Cuenca García, PhD University of Granada Department of Physiology, School of Medicine Avd. Madrid 12; 18012 Granada (Spain) MedicalResearch.com: What are the main findings of the study? Answer: In conclusion, the results of the present study showed that a higher chocolate consumption was associated with lower levels of central and total fatness in European adolescents. Of note is that the observed association was independent of total energy intake and saturated fat intake as well as objectively measured physical activity. In addition, results remained unchanged after adjusting for foods with high catechins concentration as fruit, vegetables and tea; as well as other products such as coffee that could influence the observed association between chocolate consumption and markers of total and central body fat. (more…)
Author Interviews, JAMA, Pediatrics, Weight Research / 07.11.2013

Thomas H. Inge, M.D., Ph.D. Professor of Surgery and Pediatrics Director of the Surgical Weight Loss Program for Teens Director for the Center for Bariatric Research and Innovation Cincinnati Children’s Hospital Medical CenterMedicalResearch.com Interview with: Thomas H. Inge, MD, PhD, FACS, FAAP Surgical Director, Surgical Weight Loss Program for Teens Director, Center for Bariatric Research and Innovation Attending Surgeon, Cincinnati Children’s Hospital Medical Center Professor, UC Department of Surgery Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio MedicalResearch.com: What are the main findings of the study? Dr. Inge: The mean age of the 242 participants of this observational study was 17.1±1.6 years and the median BMI was 50.5 kg/m2.  Fifty-one percent demonstrated four or more major co-morbid conditions.  Laparoscopic Roux-en-Y gastric bypass, vertical sleeve gastrectomy, and adjustable gastric banding were performed in 66%, 28%, and 6% of subjects, respectively.  There were no deaths during the initial hospitalization or within 30 days of surgery; major complications were seen in 19 subjects (8%). Minor complications were noted in 36 subjects (15%).  All re-operations and 85% of re-admissions were related to WLS. (more…)
Author Interviews, Diabetes, NYU, Weight Research / 06.11.2013

Manish Parikh MD Associate Professor of Surgery, NYU School of Medicine Director of Bariatric Surgery, Bellevue Hospital Center 550 First Ave NBV 15 South 7 New York, NY 10010MedicalResearch.com Interview with: Manish Parikh MD Associate Professor of Surgery, NYU School of Medicine Director of Bariatric Surgery, Bellevue Hospital Center 550 First Ave NBV 15 South 7 New York, NY 10010 MedicalResearch.com: What are the main findings of the study? Dr. Parikh: The main findings of this study is that surgery is safe and effective in patients with type 2 diabetes and BMI under 35.  The overall estimated rate of diabetes remission was 55% at 12 months, ranging from 33% for the adjustable gastric banding, 49% for the “mini” gastric bypass, 54% for the sleeve gastrectomy, 64% for the gastric bypass, 71% for the biliopancreatic diversion, and 81% for ileal transposition. (more…)
JAMA, Weight Research / 05.11.2013

MedicalResearch.com Interview with: Nicholas J. Christian, PhD Graduate School of Public Health University of Pittsburgh MedicalResearch.com:  What are the main findings of the study? Dr. Christian: We found that the differences between measured and self-reported weights following bariatric surgery were small and did not systematically differ by measured body mass index or degree of postoperative weight change. The average degree of underreporting by self-report was 0.7 kg for women and 1.0 kg for men. (more…)
Author Interviews, Pediatrics, Sleep Disorders, Weight Research / 05.11.2013

Chantelle Hart, Ph.D. Associate Professor of Public Health Center for Obesity Research & Education Department of Public Health 3223 N. Broad Street Philadelphia, PA 19140MedicalResearch.com Interview with: Chantelle Hart, Ph.D. Associate Professor of Public Health Center for Obesity Research & Education Department of Public Health Philadelphia, PA 19140   MedicalResearch.com: What are the main findings of the study? Dr. Hart: Following one week of sleeping their typical amount, children 8-11 years old were asked to decrease and increase their time in bed by 1.5 hours/night for one week each in random order.  Compared to when children decreased their sleep, when they increased their sleep, they reported consuming 134 kcal/day fewer, had lower fasting levels of leptin, a hunger-regulating hormone that is also highly correlated with the amount of adipose tissue, and weighed approximately 0.5 lbs less.  Reported decreases in food intake were most pronounced later in the day. (more…)
Author Interviews, BMJ, Sugar, Weight Research / 02.11.2013

MedicalResearch.com Interview with: Adam D M Briggs Academic Clinical Fellow British Heart Foundation Health Promotion Research Group, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK MedicalResearch.com: What are the main findings of the study? Answer: For the first time this study estimates the impact of a sugary drinks tax in the UK on obesity. We estimate the tax would reduce the number of adults with obesity by around 180,000 or just over 1% of all adults who are obese, and the number of adults who are either overweight or obese by 285,000. The greatest reductions are seen in young adults. We also estimate that the effects of the tax will be similar across all income groups. (more…)
Author Interviews, Prostate Cancer, Weight Research / 01.11.2013

MedicalResearch.com Interview with: Reina Haque, PhD, MPH Research scientist, Kaiser Permanente Department of Research & Evaluation MedicalResearch.com: What are the main findings of the study? Answer: The main study findings are that men who are overweight or obese when they are diagnosed with prostate cancer are more likely to die from the disease than men who are of healthy weight. In patients with more aggressive forms of prostate cancer, the researchers also found an even stronger correlation between obesity and mortality. The study was restricted to patients undergoing surgical treatment for prostate cancer, rather than other treatments such as radiation or hormone therapy. (more…)
Author Interviews, Gastrointestinal Disease, Heart Disease, Weight Research / 01.11.2013

Gianluca Iacobellis MD PhD Professor of Clinical Medicine Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, USAMedicalResearh.com Interview with: Gianluca Iacobellis MD PhD Professor of Clinical Medicine Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA MedicalResearch.com: What are the main findings of the study? Dr. Iacobellis: Our study suggests that epicardial fat, the fat pad in direct contiguity to the heart, is a good predictor of liver steatosis in obese subjects (more…)
Author Interviews, Nutrition, Pediatrics, Weight Research / 30.10.2013

MedicalResearch.com Interview Jennifer M. Poti PhD Candidate, Nutritional Epidemiology University of North Carolina at Chapel Hill MedicalResearch.com: What are the main findings of the study? Answer: Consumption of solid fat and added sugar (SoFAS) by children exceeds recommendations, but it was not known where kids obtain these “empty calories.” Analyzing data from over 22,000 US children, we found that children consumed about 1/3 of their calories as solid fat and added sugar for foods consumed from retail food stores (including grocery stores and supermarkets), schools, or fast food restaurants in 2009-2010, despite significant decreases from 1977 to 2010 at each location. These mean levels of empty calorie intake greatly exceeded recommended amounts not just for fast foods, but also for foods consumed from schools and from stores. For all survey years, foods consumed by children from schools were higher in solid fat content than foods obtained and consumed from retail food stores. (more…)
Author Interviews, Brigham & Women's - Harvard, Hearing Loss, Medical Research Centers, Vitamin D, Weight Research / 22.10.2013

MedicalResearch.com Interview with: Sharon Curhan, MD, ScM Channing Division of Network Medicine Brigham and Women's Hospital Harvard Medical School Boston, MA 02115 MedicalResearch.com: What are the main findings of the study? Dr. Curhan: The main findings of our study are that higher body mass index and larger waist circumference are associated with an increased risk of acquired hearing loss, and higher level of physical activity is associated with a decreased risk of acquired hearing loss in women. Specifically, after adjusting for potential confounders, compared with women with BMI <25 kg/m2, the relative risk for hearing loss was 25% higher for women with BMI >40. Compared with women with waist circumference <71 cm, the relative risk for hearing loss was 27% higher for women with waist circumference >88 cm. Higher physical activity was inversely related to risk; compared with women in the lowest quintile of physical activity, women in the highest quintile of physical activity had a 17% lower risk of hearing loss. Walking, the most common form of physical activity among these women, was associated with a lower risk; women who walked 2 hours per week or more had a 15% lower risk of hearing loss than women who walked less than one hour per week. These findings provide evidence that maintaining healthy weight and staying physically active, potentially modifiable lifestyle factors, may help reduce the risk of hearing loss. (more…)
Author Interviews, Weight Research / 18.10.2013

Jussi Naukkarinen, M.D., Ph.D Research Scientist Institute for Molecular Medicine Finland (FIMM) Nordic EMBL Partnership for Molecular Medicine Helsinki Finland and National Institute for Health and Welfare (THL) Division of Welfare and Health Promotion Public Health Genomics Unit and University of Helsinki School of Medicine Dept. of Medical GeneticsMedicalResearch.com Interview with: Jussi Naukkarinen, M.D., Ph.D Research Scientist Institute for Molecular Medicine Finland (FIMM) Nordic EMBL Partnership for Molecular Medicine Helsinki Finland and National Institute for Health and Welfare (THL) Division of Welfare and Health Promotion Public Health Genomics Unit and University of Helsinki School of Medicine Dept. of Medical Genetics MedicalResearch.com: What are the main findings of the study? Answer: We found in this sample of relatively young, Finnish twins that there are clearly two different kinds of obesity. While most individuals with BMIs in the "obese" category will go on to develop the usual pathologies associated with obesity (namely diabetes, hypertensio, dyslipidemia), a fraction of the obese population seems to be spared. These "metabolically healthy obese" individuals displayed a number of features that were associated with a healthy metabolic profile despite considerable overweight: a capacity for hyperplasia of the adipose tissue (as opposed to just hypertrophy) seemed to be associated with maintained mitochondrial function, lack of inflammation and liver fat. (more…)
Author Interviews, Eating Disorders, Weight Research / 17.10.2013

MedicalResearch.com Interview with Stephan  Zipfel  MD Professor of Medicine & Dean of Medical Education Head Department of Internal Medicine VI (Psychosomatic Medicine and Psychotherapy) University Medical Hospital Tuebingen President of the German College of Psychosomatic Medicine (DKPM) Co-Director of the centre for nutritional Medicine Tuebingen-Hohenheim 72076 Tuebingen / Germany MedicalResearch.com: What are the main findings of the study? Prof. Zipfel: Outpatient treatment of adults with anorexia nervosa by either enhanced cognitive-behaviour therapy, focal psychodynamic therapy, or optimised treatment as usual led to relevant weight gains and a decrease in general and eating disorder-specific psychopathology during the course of treatment. These positive effects continued beyond treatment until 12-month follow-up. Most patients completed treatment and the acceptance of both specific therapy approaches was high among both patients and therapists. (more…)
Author Interviews, Diabetes, Surgical Research, Weight Research / 14.10.2013

Dr. Mitchell S. Roslin, MD Lenox Hill Hospital Manhattan Minimally Invasive & Bariatric Surgery 186 E 76th Street, 1st Floor New York, NY 10021.MedicalResearch.com Interview with:

Dr. Mitchell S. Roslin, MD Lenox Hill Hospital Manhattan Minimally Invasive & Bariatric Surgery 186 E 76th Street, 1st Floor New York, NY 10021. MedicalResearch.com: What are the main findings of the study? Dr. Roslin: The cornerstone of medical management for weight loss and to prevent weight gain is to regulate glucose and insulin and prevent wide fluctuation.  Yet, Gastric bypass, widely considered the gold standard operation, accentuates these fluctuations.  The purpose of our study was to compare glucose tolerance of gastric bypass, sleeve gastrectomy and a modified version of duodenal switch that  preserves adequate intestine. We found that all operations improve insulin resistance, but that duodenal switch normalizes the curve, whereas gastric bypass causes wide spikes in insulin and glucose. (more…)
Author Interviews, Exercise - Fitness, Heart Disease, Weight Research / 14.10.2013

MedicalResearch.com Interview with: Christian K. Roberts Exercise and Metabolic Disease Research Laboratory, Translational Sciences Section, School of Nursing University of California, Los Angeles, CA MedicalResearch.com: How would you best summarize the main findings/results of this study? Answer: Our main finding was that HDL functioned better in its antioxidant role in subjects who participated in resistance exercise training (i.e. weight training) a minimum of 4 days a week, regardless of their weight—one group was lean (BMI <25) and the other overweight/obese (BMI >27) —than those who didn’t exercise (overweight, BMI >27, and untrained). In addition, HDL had similar effectiveness as an antioxidant in the overweight-trained group as in the as lean-trained group. Although indices of weight were associated with dysfunctional HDL, differences in fitness may be a better measure of who has healthier functioning HDL. (more…)