Certain medications, infections, and underlying health conditions (such as diabetes or autoimmune disorders) can also negatively impact mitochondrial efficiency. While...
Please note: Supplements are generally not FDA tested or approved. Some supplements can interfere with medications and/or cause side effects. Do not delay seeking medical attention for medical concerns by taking supplements without medical advice.
Excessive magnesium can cause cardiac arythmias as well as other serious side effects. Please discuss any and all supplements you take with your health care provider.
Magnesium is one of the most essential minerals that our bodies need for optimal functioning. It plays a pivotal role in over 300 biochemical reactions, including energy production, muscle function, and nervous system regulation. However, despite its importance, magnesium deficiency is quite common, with many people not getting enough of it from their diet alone. To combat this, various magnesium supplements have flooded the market, and one of the most advanced options is Glycinate 3-in-1. Developed by leading brands like Vinco Supplements, this formula promises superior absorption, offering a solution to the age-old problem of low magnesium intake. In this article, we’ll explore what Glycinate 3-in-1 is, how it works, and why it's becoming a game-changer in magnesium supplementation.
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Exercise - Fitness, Supplements / 10.04.2025
The Science Behind Intra-Workout Supplements: Boosting Performance and Fighting Fatigue
Please note: Supplements are generally not FDA tested or approved. Some supplements can interfere with medications and/or cause side effects. Do not delay seeking medical attention for medical concerns by taking supplements without medical advice.
Please discuss any and all supplements you take with your health care provider.
Intra-workout supplements are making waves among gym-goers and athletes, promising to ramp up performance, cut down on tiredness, and keep endurance strong during grueling training sessions. But what’s the real deal with these products? How do they work their effects? In this deep dive, we’ll unpack the science of intra-workout supplements—their ingredients, perks, and how they keep you going strong. We’ll stack them up against post-workout options like egg white protein, toss in a relatable story, and share some no-nonsense tips to weave them into your workouts.
What Are Intra-Workout Supplements?
Picture this: you’re halfway through a killer workout, and your energy’s starting to tank. That’s where intra-workout supplements swoop in. These are blends you sip during exercise to keep your body firing on all cylinders. Unlike pre-workout formulas that rev you up beforehand or post-workout shakes that patch you up after, these focus on fueling you in the thick of it.
So, what’s inside? You’ll typically find:
- BCAAs (Branched-Chain Amino Acids): Leucine, isoleucine, and valine—these heavy hitters help build muscle and stop it from breaking down when you’re pushing hard.
- EAAs (Essential Amino Acids): The nine must-haves your body can’t whip up solo, crucial for repairing and growing muscle.
- Carbohydrates: Quick-hitting carbs like dextrose give your muscles instant juice to keep moving.
- Electrolytes: Sodium, potassium, and magnesium keep you hydrated, fend off cramps, and keep your nerves humming.
Men's Health, Nutrition, Omega-3 Fatty Acids / 25.02.2025
How Fish Oil Benefits Men: Supporting Heart, Brain, and Joint Health
Please consult with your doctor before taking fish oil, omega-3 fatty acids or supplements of any kind. Supplements, including omega-3 fatty acids, may not be FDA approved or tested, may have side effects and may interfere with other medications you are taking.
When it comes to maintaining optimal health, men often face unique challenges. From cardiovascular risks to cognitive decline and joint issues, proactive health management is crucial. One simple yet powerful addition to a man’s diet may make a substantial difference - fish oil.
Packed with omega-3 fatty acids, fish oil benefits for men include improved heart function, sharper cognitive abilities, and healthier joints. But how exactly does it work, and why should men consider adding it to their daily routines?
The Science Behind Fish Oil and Omega-3 Fatty Acids
Fish oil is rich in omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). These essential nutrients cannot be produced naturally by the body and must be obtained through diet or supplementation.- EPA supports the body’s anti-inflammatory systems and plays a critical role in heart and joint health.
- DHA is essential for brain structure and function, aiding memory, learning, and overall cognitive performance.
Please note: Supplements are generally not FDA tested or approved. Some supplements can interfere with medications and/or cause side effects. Do not delay seeking medical attention for medical concerns by taking supplements without medical advice.
Please discuss any and all supplements you take with your health care provider and be sure to follow your provider’s recommendations for your prostate and overall health. Supplements should not be given to children, breast feeding or pregnant women without the specific advice or your medical provider.
Have you ever felt like you’re constantly battling colds or other illnesses? Whether it’s the flu season, allergy season, or just the daily grind, your immune system works hard to keep you healthy. Your immune system is your body’s defense system, protecting you from harmful germs, bacteria, and viruses. A strong immune system helps you recover quickly, while a weak one leaves you feeling run-down.
Keeping your immune system strong year-round isn’t about quick fixes. It’s about forming healthy habits and giving your body the support it needs. By making smart choices with your diet, lifestyle, and stress management, you can boost your immune health and feel your best.
In this blog, we will share practical ways to support your immune system and stay healthy throughout the year.
Eat a Balanced and Nutrient-Rich Diet
If you want a stronger immune system, start with what’s on your plate. Your body needs vitamins, minerals, and nutrients to fight off illness. Focus on adding more fruits, vegetables, whole grains, lean proteins, and healthy fats to your meals. Foods like citrus fruits, berries, spinach, nuts, and chicken give you key nutrients like vitamins C, D, and E, plus zinc. These help keep your body ready to defend you. Eating a balanced diet doesn’t have to be complicated—stick to simple, whole foods, and your body will thank you.Support Your Gut Health
A large part of your immune function is located in your digestive tract. When your gut is healthy, your body can better fight off harmful invaders. Probiotics, prebiotics, and supplements that support your gut lining can help maintain a healthy immune system. Using supplements like Mega Mucosa can help support a healthy mucosal barrier, which is essential for strong immune defenses. This supplement contains ingredients that promote microbial diversity and help maintain the gut lining. At places like Lakeland Drug Company, you can find products designed to give your immune system the support it needs. They provide trusted options to help you care for your immune health year-round. (more…)
Please note: Supplements are generally not FDA tested or approved. Some supplements can interfere with medications and/or cause side effects. Do not delay seeking medical attention for medical concerns by taking supplements without medical advice.
Please discuss any and all supplements you take with your health care provider and be sure to follow your provider’s recommendations for your prostate and overall health. Supplements should not be given to children, breast feeding or pregnant women without the specific advice or your medical provider. In addition some supplements, including berberine may interfere with other medications and prescription drugs.
Please do not ignore new or continuing gastrointestinal symptoms, as they may indicate a more serious condition including ulcers, inflammatory bowel disease, genitourinary issues and cancer. See your health care provider for specific medical advice.
When it comes to feeling your best, gut health is often the missing piece of the puzzle. Your gut isn’t just responsible for digesting food—it plays a role in everything from energy levels to immunity and even mental health. If you’ve been dealing with issues like bloating, irregular digestion, or low energy, it might be time to give your gut some extra attention.
The good news is that you don’t need drastic measures to see results. With these five simple steps, you can naturally revitalize your gut health and improve your overall well-being.
1. Include Gut-Friendly Supplements
Supplements are a simple yet effective way to give your gut the boost it needs. While diet and lifestyle changes are crucial, adding targeted supplements can speed up the process of restoring balance to your gut microbiome. One supplement to consider is berberine, a natural compound with powerful benefits for gut health. Berberine works by reducing harmful bacteria in the gut while encouraging the growth of beneficial bacteria. This makes it a potential option for improving your gut's overall environment. If you’re considering berberine, Lakeview Pharmacy offers Berberine XL, an option that’s designed for maximum absorption. Unlike other berberine products, Berberine XL is purported to be formulated for enhanced absorption, so you get the most out of every dose. Berberine benefits may extend beyond gut health, too—it’s thought to support metabolic health, reduce inflammation, and more. Just remember, supplements work best when paired with other healthy habits. Berberine should not be taken by pregnant or nursing women, women who are planning to become pregnant or children. See your health care provider for specific medical advice. (more…)
Exercise - Fitness, Supplements / 01.01.2025
A Deep Dive into Supplements for Improved Fitness of Bodybuilders
Please note: Supplements are generally not FDA tested or approved. Some supplements can interfere with medications and/or cause side effects. Do not delay seeking medical attention for medical concerns by taking supplements without medical advice.
Please discuss any and all supplements you take with your health care provider and be sure to follow your provider’s recommendations for your prostate and overall health.
Supplements for optimal fitness of bodybuilders may play a vital role in helping you achieve your goals. Whether you're aiming for faster muscle growth, enhanced performance, or quicker recovery, the right supplements can make a difference. With countless options available, it's important to understand what works best for your body and fitness journey.
By incorporating the right supplements into your routine, you may help unlock your potential and reach new heights in your training. These supplements support your efforts in and out of the gym. This blog will explore the supplements for optimal fitness of bodybuilders.
The Role of Protein Powder in Building Lean Muscle
Protein powder plays a key role in bodybuilding nutrition. It helps athletes meet their daily protein needs easily. Bodybuilders need protein to build and repair muscles effectively.
Many types of protein powders are available on the market. Whey protein is popular due to its fast absorption rate. It is great for post-workout recovery and muscle growth.
Using protein powder may also aid in reaching fitness goals. It may help boost muscle growth when paired with exercise.
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One of the best ways to ensure that you are receiving an ample supply of vitamins and minerals is to...
Gastrointestinal Disease, Microbiome, Probiotics, Supplements, Weight Research / 03.12.2024
Gut Health and Appetite Regulation: How Your Microbiome Influences Hunger
Editor's note: Please consult with your health care provider before using any supplements including probiotics.
Side effects are uncommon but may occur.
The connection between the gut and the brain is one of the most fascinating areas of research in recent years, with scientists uncovering how the microbiome—the trillions of microorganisms residing in our digestive system—can affect not just our digestion and immune system but also our feelings of hunger and satiety. As the science behind the gut-brain axis continues to unfold, it’s becoming increasingly clear that the health of our gut microbiome plays a pivotal role in regulating appetite, food intake, and body weight.
Understanding the intricate relationship between gut health and appetite regulation has profound implications for combating obesity, overeating, and eating-related disorders. In this article, we’ll explore how the microbiome influences hunger, the role it plays in appetite regulation, and what you can do to optimize gut health for better control over your hunger and eating habits. We will also look at products which aim to support a healthy microbiome and improve overall well-being.
The Gut-Brain Axis: A Two-Way Communication
The gut-brain axis refers to the bidirectional communication between the gastrointestinal system (gut) and the brain. This connection is facilitated by the vagus nerve, immune pathways, and hormones, which allow the gut and brain to send signals back and forth. Recent research has shown that gut bacteria play a significant role in this communication, influencing not only digestion but also emotions, mental health, and, importantly, appetite regulation. The microbiome, composed of bacteria, viruses, fungi, and other microorganisms, affects the brain’s perception of hunger and fullness through the production of various chemicals, including neurotransmitters, hormones, and metabolites. These signals impact brain regions that control appetite, cravings, and food intake. (more…)
Peptides alone can’t do everything. To see the best results, pair them with a healthy lifestyle. Eating a balanced diet,...
While greens powders are a convenient supplement, they should complement—not replace—a diet rich in fresh fruits, vegetables, and whole foods...
Most studies on NAD+ boosters assess their effectiveness after a few months of treatment. There is no data regarding the...
When it comes to maintaining optimal health, antioxidants are essential in protecting the body from oxidative damage. Among the various antioxidants, Vitamin E stands out as one of the most crucial players in safeguarding our cells and tissues from harm. This fat-soluble nutrient performs a variety of vital functions, particularly its role in neutralizing free radicals and supporting cellular health. In this guide, we'll explore why Vitamin E is indispensable, its different forms, the health benefits it offers, and why you should consider including it in your daily routine.
Please Note that supplemental Vitamin E carries risks, especially in patients on certain medications, including statins, niacin, Vitamin K, alkylating agents and anti-tumor antibiotics, some herbs and supplements among others.
According to the Mayo Clinic site "Oral use of vitamin E might increase the risk of prostate cancer. Use of the supplement can pose other serious risks, particularly at high doses and if you have other health conditions or have had a heart attack or stroke."
Do not supplement Vitamin E without advising your health care provider.
What is Vitamin E?
Vitamin E is not just a single compound but a group of eight fat-soluble compounds, including four tocopherols (alpha, beta, gamma, and delta) and four tocotrienols. Among these, alpha-tocopherol is the most biologically active form and is often what people refer to when talking about Vitamin E. However, the other forms, such as mixed tocopherols, also play an important role in comprehensive antioxidant defense, offering a broader range of protection against oxidative stress. (more…)
Complementary Medicine, Prostate, Supplements / 23.09.2024
Natural Supplements for Better Prostate Health: A Comprehensive Guide
Editor's note: This article discusses supplements, which in no way are intended to substitute for professional medical care and regular prostate cancer screening. Supplements are generally not FDA tested or approved. Some supplements can interfere with medications and/or cause side effects. Do not delay seeking medical attention for prostate concerns by taking supplements without medical advice.
Please discuss any and all supplements you take with your health care provider and be sure to follow your provider's recommendations for your prostate and overall health.
As men age, maintaining good prostate health becomes a top priority. The prostate, a small gland located below the bladder, plays a significant role in male reproductive health. However, many men face challenges related to this vital organ, especially as they get older. Fortunately, natural supplements can help support prostate health and overall well-being. In this article, we'll explore the benefits of these supplements, how they work, and how you can incorporate them into your lifestyle. Before we begin, it's essential to remember that supplements like Prostovit are among many that can help, but they should always be used as part of a holistic approach to health.
Why Prostate Health is Important
The prostate is crucial for producing seminal fluid, which helps transport sperm during ejaculation. Over time, the prostate may enlarge, leading to conditions like benign prostatic hyperplasia (BPH), or even develop into more severe conditions like prostate cancer. Prostate health directly impacts urinary function and quality of life, making it a critical aspect of men’s health that shouldn’t be ignored. Symptoms such as frequent urination, especially at night, difficulty starting or stopping urination, and weak urine flow are common indicators of prostate issues. Addressing these symptoms early with lifestyle changes and natural supplements may prevent more serious complications in the future. (more…)
Maintaining a healthy lifestyle is pivotal for long-term health and happiness. It's about making consistent, beneficial choices that match your needs and goals. This can be a challenging task in today's busy world, but it's certainly achievable with the right set of strategies. You can enhance your quality of life by balancing your nutrition, staying active, managing stress, and getting quality sleep. Keep reading to discover practical tips to guide you toward wellness.
A balanced diet is the cornerstone of a healthy lifestyle. Incorporating various foods from all the food groups ensures that your body gets the nutrients it needs. Increasing the intake of fruits, vegetables, whole grains, lean proteins, and healthy fats contributes to better health and helps prevent chronic diseases.
Understanding portion sizes and the significance of moderation can prevent overeating and weight gain. It is also important to stay hydrated throughout the day. Water supports metabolic processes and helps eliminate waste.
Knowing your body's calorie and nutritional requirements is crucial for maintaining a balanced diet. If you're unsure where to begin, seeking guidance from a registered dietitian can be a great starting point. For wellness products and nutritional supplements, SkinnyFit offers quality, all-natural health and wellness products—visit skinnyfit.com to explore their range.
Lastly, preparing your meals can give you more control over the ingredients and help you stick to a nutritious diet. Planning can also prevent impulsive decisions leading to unhealthy eating habits.
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Embracing Balanced Nutrition for Sustained Well-being
A balanced diet is the cornerstone of a healthy lifestyle. Incorporating various foods from all the food groups ensures that your body gets the nutrients it needs. Increasing the intake of fruits, vegetables, whole grains, lean proteins, and healthy fats contributes to better health and helps prevent chronic diseases.
Understanding portion sizes and the significance of moderation can prevent overeating and weight gain. It is also important to stay hydrated throughout the day. Water supports metabolic processes and helps eliminate waste.
Knowing your body's calorie and nutritional requirements is crucial for maintaining a balanced diet. If you're unsure where to begin, seeking guidance from a registered dietitian can be a great starting point. For wellness products and nutritional supplements, SkinnyFit offers quality, all-natural health and wellness products—visit skinnyfit.com to explore their range.
Lastly, preparing your meals can give you more control over the ingredients and help you stick to a nutritious diet. Planning can also prevent impulsive decisions leading to unhealthy eating habits.
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In recent years, the interest in herbal supplements has surged. Many people are turning to these natural alternatives to improve their health and well-being. But what role do herbal supplements play in modern medicine? Are they truly effective, or just a trend? In this article, we'll explore the intersection of herbal supplements and modern medicine, uncovering the benefits, risks, and scientific perspectives on this growing phenomenon.
Please remember most herbal medications and supplements are not FDA approved or tested. Many have side effects especially in combination with other medications or supplements. Please consult with your health care provider before taking any supplements you are considering taking and be aware of potential side effects. Supplements should not be used during pregnancy or while nursing without the express permission of your health care provider.
A Brief History of Herbal Medicine
Herbal medicine has been around for thousands of years. Ancient civilizations like the Egyptians, Chinese, and Greeks used plants to treat various ailments. In fact, many of today's pharmaceuticals have their roots in herbal remedies. For instance, aspirin was derived from willow bark, and digitalis, used to treat heart conditions, comes from the foxglove plant. Despite the rise of synthetic drugs, herbal medicine never entirely disappeared. Instead, it evolved, and are widely available today at both brick and mortar stores to online platforms like Pravdao.sk. Today, we see a blend of ancient wisdom and modern science in the world of herbal supplements.(more…)
Endocrinology, Supplements, Thyroid Disease / 17.07.2024
Thyroid Health: Should you take Thyroid-Specific supplements?
Find out if thyroid-specific supplements are right for you, the benefits, and the risks....
Author Interviews, Cancer Research, Nutrition, Supplements / 06.01.2022
Mistaken Beliefs About Supplements and Vitamins Among Cancer Patients
MedicalResearch.com Interview with:
Dr Rana Conway PhD RNutr
Research Fellow
Energy Balance & Cancer Group, and Obesity Research Group
Research Department of Behavioural Science and Health
University College London
MedicalResearch.com: What is the background for this study?
Response: We’ve seen great advances in cancer diagnosis and treatment in recent years which means the number of people living with and beyond a cancer diagnosis is rapidly increasing. The WCRF and CRUK recommend improving diet and exercise to reduce the risks of cancer coming back but we know anecdotally that supplements are sometimes seen as an easier option, and people who’ve had cancer are often interested to know if they should be taking any supplements. (more…)
Author Interviews, Supplements, Vitamin D / 29.05.2020
Giving Your Body What It Needs: 6 Nutritional Supplements Everyone Should Consider Adding Into Their Diet
It is important to remember that the FDA does not regulate dietary supplements. This means that, unlike medications and drugs,...
Author Interviews, Fertility, NIH, Supplements / 08.01.2020
Study Evaluates Zinc + Folic Acid Supplements on Semen Quality
MedicalResearch.com Interview with:
Enrique Schisterman, Ph.D.
Chief, Epidemiology Branch, DIPHR
Eunice Kennedy Shriver National Institute of Child Health and Human Development
NICHD
MedicalResearch.com: What is the background for this study?
Response: Small studies indicated that zinc and folic acid supplements for men might improve semen quality as both zinc and folic acid are involved in DNA transcription and have antioxidant functions. But no large-scale randomized trials have been done to assess efficacy, which is important since dietary supplements are largely unregulated, and FDA cannot regulate supplements until after they come to market. Some male fertility-targeted supplements are already among the most commonly sold supplement products, despite the lack of data to guide their use. (more…)
Author Interviews, Diabetes, Supplements / 08.01.2020
Could a Ketone Drink Help Keep Blood Sugar Under Control?
MedicalResearch.com Interview with:
Jonathan P. Little PhD
Associate Professor Canadian Institutes of Health Research New Investigator
Michael Smith Foundation for Health Research Scholar
Faculty of Health and Social Development
School of Health and Exercise Sciences
The University of British Columbia Syilx Okanagan Nation Territory
Kelowna, BC Canada
MedicalResearch.com: What is the background for this study?
Response: Ketones are energy-yielding molecules that are bodies naturally produce during periods of starvation or when we restrict carbohydrate intake. Recently, scientists from Oxford and the NIH have created exogenous ketone supplements, which now enable us to be able to drink ketones. This puts our body into a unique state – we can consume a drink that raises blood levels of ketones without having to starve or restrict carbohydrate intake. Some are even touting ketone supplements as a “fourth macronutrient”.
Ketone supplements are primarily marketed for athletes to provide an alternative fuel for improving endurance exercise performance. We were actually studying how ketone supplements impacted exercise performance when we noticed that they consistently lowered blood glucose after participants consumed them. We went to the literature and found some classic papers where it was shown that infusing ketones did in fact lower glucose and the mechanism seemed to involve reducing liver glucose output. This was very exciting to us because we also study type 2 diabetes, a condition where blood sugars are too high and elevated liver glucose output is one of the major reasons. So we came up with the hypothesis that ketone supplements might be a unique strategy to help with blood glucose control.
In the recent study, we tested this out in a randomized crossover experiment in 15 participants with overweight/obesity who were at risk for type 2 diabetes. Participants drank the ketone monoester supplement or a placebo and 30 minutes later they consumed an oral glucose tolerance test drink containing 75 grams of sugar. Blood samples were collected for 2 hours after the glucose test drink.
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Author Interviews, Brigham & Women's - Harvard, Cognitive Issues, JAMA, Supplements / 16.12.2019
Non-FDA Approved Piracetam Found in Some Supplements Marketed for Cognitive Function
MedicalResearch.com Interview with:
Pieter A. Cohen, MD
Department of Medicine, Cambridge Health Alliance
Somerville, Massachusetts
Harvard Medical School
Boston, Massachusetts
MedicalResearch.com: What is the background for this study?
Response: There has been increasing interest in the use of over-the-counter supplements to help improve memory and cognitive function. However, prior studies have suggested that these types of supplements might contain unapproved investigational drugs.
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Annals Internal Medicine, Author Interviews, Supplements, Vitamin C, Vitamin D / 09.07.2019
Most Supplements Found to Not Decrease Risk of Heart Attack, Stroke or Death
MedicalResearch.com Interview with:
Safi U. Khan, MD
Department of Internal Medicine
Robert Packer Hospital
Sayre, PA 18840
MedicalResearch.com: What is the background for this study?
Response: There is substantial body of observational data favoring use of vitamins, supplements and special diets for improving cardiovascular health. However, such type of data is limited by various biases. Randomized controlled trial (RCT) is considered gold standard to evaluate effects of a therapy. (more…)
Author Interviews, Hip Fractures, JAMA, Supplements / 13.05.2019
Excessive Supplements Linked to Increased Risk of Hip Fractures
MedicalResearch.com Interview with:
Prof. Haakon E Meyer, PhD
Department of Public Health and Global Health
Norwegian Institute of Public Health
Oslo, Norway
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: The use of high dose vitamin supplementation is popular in parts of the population, often without any clear indication and in the absence of clear evidence of benefit.
However, side effects can occur, and in a previous published secondary analysis of double blinded randomized controlled trials, we found to our surprise an increased risk of hip fracture in those supplemented with high doses of vitamin B6 in combination with vitamin B12.
This finding was re-assessed in the current study employing data from the large observational Nurses' Health Study. As in the previous study, we found that a combined high intake of vitamin B6 and B12 was associated with increased risk of hip fracture. (more…)
Author Interviews, Depression, Nutrition, Supplements, Weight Research / 08.03.2019
Supplements Did Not Prevent Depression in Study of Obese Adults
MedicalResearch.com Interview with:
Prof. Marjolein Visser PhD
Professor of Healthy Aging
Head section Nutrition and Health
Department of Health Sciences, Vrije Universiteit Amsterdam
Amsterdam Public Health research institute
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: More than 40 million Europeans experience a major depressive disorder. One in ten men, and one in five women suffer from clinical depression at least once during their lifetime. Depression is one of the most prevalent and disabling disorders in the EU.
Given the increasing prevalence of depression, more people are actively searching for ways to decrease their risk through lifestyle modification, but are often overwhelmed by confusing and contradictory information.
The MooDFOOD prevention trial is the largest randomized clinical trial to study the effects of nutritional strategies on the prevention of major depressive disorder. Over 1000 overweight or obese participants identified as being at elevated risk for depression but who were not currently depressed, from four European countries -the Netherlands, the United Kingdom, Germany and Spain, took part in the study. Participants were randomized to either take nutritional supplements containing folic acid, vitamin D, zinc, selenium or to a pill placebo, and half of participants also received a behavioral lifestyle intervention intended to change dietary behaviors and patterns.
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Author Interviews, Cancer, Cancer Research, Supplements / 30.01.2019
Antioxidants May Enhance Efficacy of Chemotherapy on Glioblastoma
MedicalResearch.com Interview with:
Dr. Scott Litofsky, MD
Division of Neurological Surgery
University of Missouri-Columbia School of Medicine
Columbia, MO 65212
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Many patients take over-the-counter medications to held their cancers. Some of these remedies may be helpful; others are potentially harmful. Anti-oxidant medications are frequently selected by patients as they are inexpensive and available.
We were approached by a high school student, Macy Williams (one of the authors) to do some research in our laboratory when she won a research scholarship (the 2016 Emperor Science Award) from Stand Up to Cancer. She worked with us several times per week doing experiments during her senior year of high school. When she graduated, we continued the work that she started.
We studied effects of Vitamin D3, Melatonin, and alpha-Lipoic Acid on glioblastoma cells, a highly malignant brain tumor. We included experiments of these agents alone and in combination with Temozolomide, a chemotherapy agent used as standard of care in glioblastoma. The work was done in cultured cells, measuring growth and survival of cells. We used concentrations that could be achieved by oral intake of the drugs.
We found that antioxidant medications, particularly alpha Lipoic Acid, had synergistic effects with Temozolomide – that is Temozolomide impair glioblastoma cell growth and survival better when combined with an antioxidant. The mechanism of action may be through reactive oxygen species. (more…)
Author Interviews, JAMA, Supplements / 23.10.2018
Banned Stimulants Remain in Supplements, Despite FDA Efforts to Remove Them
One of the most concerning findings was that one stimulant appeared in the supplements analyzed only after the FDA warned...
Author Interviews, JAMA, Mental Health Research, Omega-3 Fatty Acids / 15.09.2018
Omega-3 Fatty Acids May Reduce Anxiety
MedicalResearch.com Interview with:
Yutaka MATSUOKA, MD, PhD
Division Chief of Health Care Research,
Behavioral Sciences and Survivorship Research Group,
Center for Public Health Sciences,
National Cancer Center Japan
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Anxiety is the most commonly experienced psychiatric symptom. We have now two major treatment options that include cognitive-behavioral therapy (CBT) and pharmacotherapy. However, CBT is time-consuming, costly, and limited in availability. And there is concern over potential side effects in pharmacotherapy. Evidence-based and safer treatment options are required. Omega-3 fatty acids have potential preventive and therapeutic effects on depression and anxiety. Clinical and preclinical studies support the effectiveness of omega-3 fatty acids as a treatment for anxiety disorders. Despite the largely positive findings of these trials, the clinical application of the findings is unfortunately limited by their small sample size.
Improvement in anxiety symptoms were associated with omega-3 fatty acids treatment compared with controls. The anxiolytic effects of omega-3 fatty acids were also stronger in patients with clinical conditions than in subclinical populations. (more…)
Yutaka MATSUOKA, MD, PhD
Division Chief of Health Care Research,
Behavioral Sciences and Survivorship Research Group,
Center for Public Health Sciences,
National Cancer Center Japan
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Anxiety is the most commonly experienced psychiatric symptom. We have now two major treatment options that include cognitive-behavioral therapy (CBT) and pharmacotherapy. However, CBT is time-consuming, costly, and limited in availability. And there is concern over potential side effects in pharmacotherapy. Evidence-based and safer treatment options are required. Omega-3 fatty acids have potential preventive and therapeutic effects on depression and anxiety. Clinical and preclinical studies support the effectiveness of omega-3 fatty acids as a treatment for anxiety disorders. Despite the largely positive findings of these trials, the clinical application of the findings is unfortunately limited by their small sample size.
Improvement in anxiety symptoms were associated with omega-3 fatty acids treatment compared with controls. The anxiolytic effects of omega-3 fatty acids were also stronger in patients with clinical conditions than in subclinical populations. (more…)
Author Interviews, Brigham & Women's - Harvard, Heart Disease, Supplements / 09.09.2018
Cardiac Stimulant Found in Some OTC Supplements
MedicalResearch.com Interview with:
Pieter Cohen, M.D.
Associate Professor of Medicine
Cambridge Health Alliance
Assistant Professor of Medicine
Harvard Medical School
MedicalResearch.com: What is the background for this study?
Response: Dietary supplements lead to an estimated 23,000 emergency department visits each year in the United States (US), and weight loss and sports supplements contribute to a disproportionately large number of these emergency department visits. It is not known which ingredients in weight loss and sports supplements pose the greatest risk to consumers, but there are stimulants found in botanical remedies that might pose risks.
In the current study, we investigated the presence and quantity of higenamine a stimulant found in botanicals and available in sports and weight loss supplements sold in the US.
(more…)
Author Interviews, Colon Cancer, Supplements / 13.04.2018
Could Some Iron Supplements Raise Your Risk of Colon Cancer?
MedicalResearch.com Interview with:
Nathalie Scheers PhD
Asst. Professor
Chalmers University of Technology
Dept of Biology and Biological Engineering
Food and Nutrition Science
Göteborg, Sweden
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Many different forms of iron supplements are used to treat iron deficiency symptoms or as phosphate binders in patients with renal disease. two of these iron supplements, the chelates ferric citrate and ferric EDTA have been observed to drive colon cancer in mice. In the newly published study in Oncotarget, we are reporting our work on how these iron compounds differ compared to the simple salt ferrous sulphate, which is another common iron supplement.
The main finding of this study was that ferric citrate and ferric EDTA promoted the cancer biomarker amphiregulin which in turn activated the MAP kinase ERK in gut epithelial cancer cells. There were no such effects in ferrous sulphate-treated cells. (more…)
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