Author Interviews, COVID -19 Coronavirus, Lung Cancer / 27.03.2020

MedicalResearch.com Interview with: Dr. Amy C. Moore PhD Director of Science and Research GO2 Foundation for Lung Cancer MedicalResearch.com: What is the mission of the GO2 Foundation for Lung Cancer? Response: GO2 Foundation for Lung Cancer’s mission is to transform survivorship by  saving, extending, and improving the lives of those vulnerable, at risk, and diagnosed with lung cancer. (more…)
Author Interviews, COVID -19 Coronavirus, Duke / 27.03.2020

MedicalResearch.com Interview with: Dr. Rupesh Agrawal, MD Associate Professor Senior Consultant Ophthalmologist Duke-NUS Medical School, Singapore MedicalResearch.com: What is the background for this study? Wasn't Dr Li Wenliang, the Chinese physician who first alerted his community of coronavirus an opthalmologist, with possible exposure to tears from this surgical work with glaucoma patients? Response: Since the start of the pandemic, there have been multiple reports which suggested the transmission of SARS-CoV-2 via ocular fluids. As ophthalmologists, we come into close contact with tears on a daily basis during our clinical examination. Furthermore, many equipment in the clinic like the Goldman tonometer come into direct contact with such ocular fluids, providing a channel for viral transmission. The evidence, as of date, were mainly anecdotal reports included in newspaper articles and media interviews. We wanted to know if the virus can truly be found in tears, so we decided to embark on this study. (more…)
Author Interviews, COVID -19 Coronavirus, Pharmaceutical Companies, Vaccine Studies / 17.03.2020

MedicalResearch.com Interview with: Nathalie Charland PhD Senior Director, Scientific and Medical Affairs Medicago  MedicalResearch.com: What is the background for this study? What are the main findings? Response: We started to work on solutions as soon as we were able to obtain the appropriate genetic information for the new COVID-19. Medicago is committed to advancing therapeutics against life-threatening diseases worldwide.  (more…)
Author Interviews, COVID -19 Coronavirus / 16.03.2020

MedicalResearch.com Interview with: Sibaji Sarkar, Ph.D. Adj. Professor Quincy College, Quincy, Boston MA MBC College, Wellesley MA RC College, Boston, MA  MedicalResearch.com: What is the background for this study? Response: COVID-19 infection is spreading and nothing is out there now to stop it. Hopefully, vaccines will be made and will be useful but that may take months if not a year. Researchers are also testing the use of other anti-viral drugs. COVID-19 uses (angiotensin converting enzyme receptor 2) ACE2 on capillary membranes of lungs to attach and then enter by endocytosis. ACE and ACE2 are two different types of receptors. ACE inhibitors are regularly in use as blood pressure lowering drugs. Unfortunately, ACE inhibitors have very les affinity for ACE2. Theoretically, if COVID-19 and any ACE2 inhibitor share similar binding site on ACE2 or at least bind in close proximity, assuming the virus is a big particle, it should fully or partially block viral entry. That will reduce or delay disease progression. (more…)
Author Interviews, COVID -19 Coronavirus, Vaccine Studies / 13.03.2020

MedicalResearch.com Interview with: Cynthia Liu,  Ph.D. Manager, Scientific Information CAS, a division of the American Chemical Society Columbus, OH 43210 MedicalResearch.com: What is the background for this study? Response: The outbreak of COVID-19 caused by the new virus SARS-CoV-2 has overwhelmed the health systems in many countries and been declared by WHO as a pandemic which will continue to affect global public health and world economy. This threat calls for an intensified effort in the development of therapeutic agents and vaccines. CAS is a not-for-profit division of the American Chemical Society that specializes in scientific information solutions. Our team includes hundreds of scientists that build a global data collection of curated scientific content from both journal articles and patent applications as well as chemical and biological substance collections. With this report, our team hopes to support the efforts of R&D organizations seeking to address this crisis by providing an up-to-date overview of recent relevant publications and insight into potential therapeutic agents, including both small molecules and biologics. (more…)
Author Interviews, COVID -19 Coronavirus, CT Scanning, Global Health, Medical Imaging, RRS_Radiology / 13.03.2020

MedicalResearch.com Interview with: Soheil Kooraki  MSR MS, MD on behalf of Dr. Ali Gholamrezanezhad MD and co-authors Department of Radiological Sciences, David Geffen School of Medicine, University of California at Los Angeles Los Angeles, California MedicalResearch.com: What is the background for this study? What are the main findings? Response: COVID19 is a novel strain of the coronavirus family causing pneumonia. Two similar strains were discovered in 2003 and 2012 to cause the so-called SARS and MERS outbreaks, respectively. Radiologists need to be prepared for the escalating incidence of COVID-19. We reviewed the literature to extract the epidemiologic and imaging features of SARS and MERS in comparison with known imaging features of COVID-19 pneumonia to have a better understanding of the imaging features of the COVID19 pneumonia in acute and post-recovery stages. (more…)