MedicalResearch.com - Latest news, interviews, and insights into medical research, health and wellness, fitness and addiction.
Surgical Research, Weight Research / 14.10.2024

  Maintaining a healthy weight is important at any age, but it becomes even more crucial as we grow older. For seniors, managing weight can help improve overall well-being, reduce the risk of chronic diseases, and increase mobility and independence.   However, weight loss strategies that might work for younger people aren’t always appropriate for older adults. Seniors need safe, effective methods tailored to their unique physical, mental, and nutritional needs.   This article will explore some safe and effective weight loss strategies for seniors, focusing on ways to stay fit and healthy while maintaining energy and strength. (more…)
Semaglutide, Weight Research / 23.09.2024

Ozempic (semaglutide) is a prescription medication designed to help manage type 2 diabetes. It belongs to a class of drugs called GLP-1 receptor agonists, which work by increasing insulin production, reducing blood sugar levels, and slowing digestion to help improve glucose control. Ozempic has also gained attention for its potential role in weight management, but its primary use is for patients with type 2 diabetes who need help controlling their blood sugar. ozempic-weightloss To get the best results from Ozempic, following the correct dosing schedule is critical. A structured approach to dosage allows the body to adjust to the medication, reduces the likelihood of side effects, and ensures that patients achieve optimal blood glucose control over time. Many people also explore options to buy Ozempic from Canada as a way to save on costs while maintaining their treatment regimen In this article, you will learn about Ozempic dosing, how to follow the dosing schedule, where to inject, what to do if you miss a dose, and more. Read on to find out how you can also save on Ozempic when you order through BuyCanadianInsulin.com. Editor' note: If you are purchasing Ozempic from Canada, please ensure it is legal where you live and that you are not purchasing a counterfeit product. (more…)
Semaglutide, Weight Research / 18.09.2024

If you’ve been hearing a lot of buzz about the Wegovy pen and are curious about what it can do for weight loss, you're in the right place. There’s a lot to understand, but we’re going to break it down into simple, easy-to-follow information. Whether you're exploring your options or have already made up your mind about giving it a try, here's everything you need to know about the Wegovy pen.

What is the Wegovy Pen?

Let’s start with the basics. The Wegovy pen is a once-weekly injectable medication that’s used to support weight loss in adults. It contains the active ingredient semaglutide, which is designed to help regulate appetite. In simple terms, it helps you feel fuller for longer, so you're less likely to overeat. Semaglutide mimics a hormone called GLP-1 (glucagon-like peptide-1), which plays a role in controlling hunger. By imitating this hormone, Wegovy helps reduce food cravings and manages how much you eat. (more…)
Weight Research / 09.09.2024

Tirzepatide is an innovative medication recently making waves in the treatment of type 2 diabetes and obesity. Known by its brand names, Mounjaro and Zepbound, this medication is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. While its efficacy in managing blood glucose levels and supporting weight loss is noteworthy, it’s crucial for patients and healthcare providers to fully understand the potential side effects associated with tirzepatide. This article delves into the detailed aspects of tirzepatide side effects, providing key insights for those considering this medication.

What is Tirzepatide?

Tirzepatide belongs to a new class of medications designed to manage blood sugar in adults with type 2 diabetes. It works by mimicking the action of two incretin hormones—GIP and GLP-1—which help regulate insulin secretion, slow down gastric emptying, and reduce appetite. These combined effects make tirzepatide particularly effective for controlling blood sugar levels and promoting weight loss, making it a dual-action treatment option. (more…)
Nutrition, Weight Research / 04.09.2024

Semaglutide has emerged as a promising medication for weight loss, offering significant results for many users. Wegovy's semaglutide , a glucagon-like peptide-1 (GLP-1) receptor agonist, works by mimicking a natural hormone that regulates appetite and food intake. Combining semaglutide with healthy lifestyle changes can accelerate weight loss and improve overall outcomes. While semaglutide alone can lead to impressive weight reduction, there are strategies to enhance its effectiveness. Eating a nutritious, low-calorie diet rich in fiber and protein can complement the appetite-suppressing effects of the medication. Regular physical activity further supports weight loss efforts and overall health improvements. It's important to note that the full effects of semaglutide may take several weeks to become noticeable. Patience and consistency are key when using this medication for weight management. As with any weight loss journey, individual results may vary, but many users experience significant reductions in body weight over time.

Key Takeaways

  • Semaglutide mimics GLP-1 to regulate appetite and food intake
  • Combining the medication with a healthy diet and exercise enhances weight loss
  • Consistency and patience are crucial for optimal results with semaglutide
(more…)
Surgical Research, Weight Research / 03.09.2024

Making the decision to seek bariatric surgery is one to make only once you are sure you are ready for it. This is a life-changing experience and one that requires a significant amount of work. Yet, the results are often highly desirable and could even extend your life while improving your well-being. To determine if weight loss surgery is the best decision for you, take the time to learn as much as you can about the process and the results. Take into consideration your health and long-term well-being. The first step is to meet the medical guidelines required by most doctors and surgeons to obtain bariatric surgery. These typically include:
  • Body mass index (BMI) rating of 40 or higher, though some doctors may consider 35 or higher.
  • Have a lower BMI but health complications that make losing weight quickly helpful
  • For those who are younger, including adolescents, you may need to have a BMI of at least 40 to qualify
While your bariatric surgeon will offer insight into when this type of care is best suited for you, it helps to consider the other factors that may also play a role in whether or not you are ready for weight loss surgery. (more…)
Exercise - Fitness, Technology, Weight Research / 02.09.2024

Technology has revolutionized and reshaped the modern fitness industry in recent years. Its role in the fitness sphere has shifted from supporting to key, changing how people approach health and wellness. With the rise of mobile apps, wearable technology, and smart scales, staying on top of your health has never been easier and more accessible. This fitness technology is available to everyone, catering to various preferences and fitness levels. As a result, people get to optimize their workouts, track their progress, and adopt healthier lifestyles. Some tools include personalized plans, nutritional advice, and a more holistic view of one’s health. Continue reading to learn more about how fitness apps and smart scales can help you track and achieve your goals and adopt a better approach to your health. (more…)
Diabetes, Weight Research / 28.08.2024

Editor's note:  Compounding is allowed when there is a shortage of the drug involved, but legal restrictions should be followed.  In recent years, the world of diabetes management has seen a major breakthrough with GLP-1 receptor agonists like Tirzepatide. These cutting-edge therapies aren't just about controlling blood sugar levels; they represent a fundamental shift in how we manage chronic diseases. Tirzepatide and other GLP-1 drugs have captured the attention of the medical community and patients alike because of their potential to enhance overall health and promote longevity. Thanks to recent studies, we're seeing a future where diabetes management goes beyond traditional approaches. Instead, we're moving into a world of comprehensive metabolic health where we can hope for a healthier, longer life. It's exciting to think about what these new therapies could mean for people living with diabetes and how they could change the broader landscape of healthcare. Tirzepatide is an incredible medication that boasts a unique dual action mechanism as both a GLP-1 and GIP receptor agonist. This one-of-a-kind attribute means that Tirzepatide is able to offer an array of benefits in regards to glucose control. By increasing insulin secretion and reducing glucagon levels, Tirzepatide assists with blood sugar regulation in a powerful way.  Tirzepatide has also been shown to be a valuable tool in managing obesity, which is a common comorbidity in type 2 diabetes. The weight loss properties of this medication have been linked to improved metabolic outcomes and reduced cardiovascular risk. Truly, Tirzepatide is a force to be reckoned with in the medical community. (more…)
Surgical Research, Weight Research / 27.08.2024

Gastric balloons are a popular non-surgical treatment for weight loss, thanks to their effectiveness in helping patients lose weight by restricting food intake and experiencing a feeling of fullness. Although the procedure might be similar regardless of the option chosen by the patient, Spatz3 is the only gastric balloon in the market that has the possibility of adjusting its size. This proposes various benefits that make the success rate score higher than with non-adjustable gastric balloons.

WHAT IS A GASTRIC BALLOON

To understand the differences between an adjustable and non-adjustable gastric balloon, first, we need to understand how they work. A gastric balloon is made of silicone rubber that’s inserted through the mouth and placed in the stomach using an endoscope. Once it’s in the stomach, it’s filled with saline solution to take up space. Because of the lack of space around it once filled, the patient will feel satiated quicker, eat less, and therefore, lose weight. The procedure usually takes 15 minutes, and the patient can go home once the sedation wears off. The first two weeks after the procedure, the patient will be on a liquid diet and gradually transition to solid food. Usually, the healthcare professionals will offer other guidelines, such as a recommended diet or workout plan, so that the patient continues losing weight not only while the gastric balloon is inside but also after it’s been removed. Unless there is any intolerance issue, the balloon will remain in the patient’s stomach for six months. Once it’s removed, he or she is expected to continue practicing the same healthy habits to maintain the weight loss. (more…)
Pharmacology, Semaglutide / 11.08.2024

Oral Semaglutide has emerged as a significant advancement in the realm of weight loss treatments. As an alternative to traditional injectable options, oral Semaglutide offers convenience and effectiveness. This guide provides an in-depth look at oral Semaglutide, its benefits, how to access it through prescriptions, and explores compounded semaglutide online.

What is Oral Semaglutide?

Oral Semaglutide is an oral form of the medication Semaglutide, which was originally available only as an injection. It is used to manage weight loss and control blood sugar levels in individuals with obesity or type 2 diabetes.
  • Mechanism of Action: Semaglutide mimics a hormone called GLP-1, which helps regulate appetite and insulin secretion. By enhancing these processes, it can support significant weight loss and better blood sugar control.
  • Approval and Usage: The oral version is approved by the FDA for weight management and is typically prescribed as part of a comprehensive weight loss plan that includes diet and exercise.
(more…)
Diabetes, Weight Research / 25.07.2024

Introduction to Tirzepatide Weight loss injections have gained significant attention over the years, with many people seeking effective solutions to combat obesity. The Tirzepatide weight loss injection is one of the latest breakthroughs in this area. But how does this new treatment differ from other weight loss injections? Let's delve into the unique characteristics and benefits of Tirzepatide compared to its counterparts. Tirzepatide has been making waves due to its impressive efficacy in promoting weight loss. Unlike traditional methods focusing solely on diet, exercise, or other medications, Tirzepatide offers a novel approach by leveraging the body's natural hormonal responses. This article aims to provide a comprehensive overview of how Tirzepatide stands out among the plethora of weight loss treatments available today. (more…)
Weight Research / 15.07.2024

Let's talk about something we all think about but rarely understand deeply—obesity and metabolism. There's a lot of noise out there, and it's easy to get lost in the myths. So, let's cut through the confusion. Get ready to get real information about how our bodies work and why we gain weight.

Obesity: An Overview

Obesity isn't just about carrying a few extra pounds; it's a chronic condition characterized by an excessive accumulation of body fat. It's typically measured using the Body Mass Index (BMI). A BMI of 30 or higher indicates obesity. This excess body fat can have serious consequences for your health. It increases the risk of many health conditions, including type 2 diabetes, heath disease, and varicose veins. Seeking a nutrition and considering a vein treatment in Philadelphia can provide targeted treatments for obesity-related issues. 

Causes of Obesity

Some of the factors that increase the risk of obesity include: - Poor diet - Lack of physical activity - Genetics - Psychological factors (more…)
Author Interviews, Pediatrics, USPSTF, Weight Research / 25.06.2024

MedicalResearch.com Interview with: John M. Ruiz, Ph.D Associate Professor of Clinical Psychology Department of Psychology University of Arizona Dr. Ruiz is the incoming editor-in-chief of the American Psychological Association (APA) journal, Health Psychology Dr. Ruiz joined the U.S. Preventive Services Task Force in January 2022 MedicalResearch.com: What is the background for this study? What are the main findings? Response: Almost 20 percent of children and teens in the United States have a high body mass index (BMI), the standard measure of obesity. However, there are proven ways that clinicians can help kids and teens manage their weight and stay healthy. We found that intensive behavioral interventions can help children age 6 and older who have a high BMI both achieve a healthy weight and improve their quality of life.  (more…)
Weight Research / 10.06.2024

Key Takeaways
  • Personalized weight management is crucial in achieving sustainable results.
  • Combined data from multiple sources enhances personalization.
  • Maintaining a relationship between providers and consumers boosts success rates.
The Need for Personalization in Weight Management Personalized weight management plans are essential in today's health-focused world, and research consistently shows their effectiveness over generic approaches. According to a study by the Centers for Disease Control and Prevention (CDC), customized weight management strategies lead to tremendous long-term success in weight loss. Additionally, platforms like BuildMyBod offer providers a turnkey solution to offer diverse services that cater to personal health needs, showing how personalization is becoming a cornerstone in weight management. (more…)
Author Interviews, Diabetes, Orthopedics, Weight Research / 14.02.2024

MedicalResearch.com Interview with: Matthew Magruder, MD PGY3 Orthopaedic Residency Program Department of Orthopaedic Surgery and Rehabilitation Maimonides Medical Center MedicalResearch.com: What is the background for this study? Response: The prevalence of obesity and diabetes mellitus has reached epidemic proportions. Approximately 37.3 million people in the United States, accounting for 11.3% of the total population, have diabetes, and 100.1 million, or 41.9%, of all US citizens are obese. Furthermore, these numbers are only projected to increase in the coming decades. This is an issue for orthopaedic surgeons because diabetes and obesity have consistently been demonstrated to be risk factors for complications following total joint replacements, especially total hip replacements. Therefore, we are in desperate need of new and more effective tools in mitigating the risk of poor outcomes in our joint replacement patients. Semaglutide, and other GLP-1 agonists, are potentially a new tool that can be used to help decrease the risks following joint replacement surgery. Initially a medication to treat diabetes, semaglutide has recently been approved by the FDA to treat obesity as well, as randomized controlled trials have consistently demonstrated significant weight loss with minimal side effects. The purpose of our study was to see what effect the use of semaglutide had on total hip arthroplasty patient outcomes. (more…)
Weight Research / 01.02.2024

Bariatric surgery has a long history of proven successes. It helps to lose excess weight and empowers the individual to enjoy a fulfilling life. Losing weight is one of the prime benefits that propel people to undergo the knife. When considering Denver bariatric surgery services, patients experience other benefits. The benefits include better pain relief, cardiovascular health, hypertension, diabetes management, and mental health. When a person suffers from obesity and weight-associated health issues, bariatric surgery enhances the quality of life. Reverse Serious Diseases and Health Issues Several clinical studies show that bariatric surgery reverses long-term Type 2 diabetes. Weight loss helps lower blood cholesterol and blood sugar and reduce the risk of strokes and heart diseases. The surgery gives hope to several patients with Type 2 diabetes to stop using insulin and medications. One simple surgery reverses serious health issues and enhances overall well-being. Individuals enjoy leading more active lives by eliminating long-term health conditions. To maintain a high-quality life, patients must maintain their lifestyle to experience the benefits of bariatric surgery in the long term. (more…)
Alzheimer's - Dementia, Author Interviews, Weight Research / 28.11.2023

MedicalResearch.com Interview with:

Mahsa Dolatshahi, M.D., M.P.H. Post-doctoral research fellow Mallinckrodt Institute of Radiology (MIR) Washington University School of Medicine St. Louis MedicalResearch.com: What is the background for this study? Response: Obesity at midlife is recognized as a risk factor for developing Alzheimer disease decades afterwards. However, body mass index on its own does not adequately represent the risks associated with obesity. In this study, we went beyond BMI and considered anatomical distribution of body fat, including the metabolically active visceral fat in the belly, and showed its association with Alzheimer pathology in the form of amyloid proteins. In addition, visceral fat along with obesity and insulin resistance were associated with thinning of brain cortex, as early as midlife. (more…)
Author Interviews, Weight Research / 16.10.2023

MedicalResearch.com Interview with: John A. Batsis, MD, FACP, AGSF, FGSA, FTOS Associate Professor Division of Geriatric Medicine, School of Medicine Department of Nutrition, The Gillings School of Global Public Health Chapel Hill, NC 27599 MedicalResearch.com: What is the background for this study? Response: The rationale for this study is that there has been a flurry of new medications that have been approved for the treatment of obesity in older adults. MedicalResearch.com: What are the main findings? Response: Our main findings are that the rates of weight loss promoting (WLP) medications (those that are prescribed for weight loss or have evidence that lead to significant weight loss) are rising and that there is a robust association between the rates of limitations (physical limitations, instrumental activities of daily living, and basic activities of daily living) and the use of weight loss promoting medications. In those persons with obesity, older adults taking weight loss promoting have higher rates of being of physical limitations. (more…)
Author Interviews, Dermatology, Diabetes, Heart Disease, Weight Research / 28.08.2023

MedicalResearch.com Interview with: Dr. Alexis Elias Malavazos Endocrinology Unit Clinical Nutrition and Cardiovascular Prevention Service, IRCCS Policlinico Unit of Radiology, IRCCS Policlinico San Donato, San Donato Milanese, Italy   MedicalResearch.com: What is the background for this study? Response: Psoriasis is a systemic inflammatory disease often associated with obesity and type-2 diabetes (T2D). The inflammatory process of psoriasis can target adipose tissue depots, particularly those surrounding the heart and the coronary arteries, exposing them to an increased risk of cardiovascular disease. (more…)
Author Interviews, Endocrinology, Gender Differences, Weight Research / 16.06.2023

MedicalResearch.com Interview with: Francesca Galbiati, MD Clinical/Research fellow in Endocrinology Massachusetts General Hospital MedicalResearch.com: What is the background for this study? Response:  Arginine-vasopressin (AVP) is a neurohormone well known for its role in water balance regulation. It promotes renal water absorption in the kidney, to maintain normal sodium levels in the blood via a tightly controlled osmotic regulation. Besides AVP classical role, data have shown that AVP effects extend beyond water balance regulation. Animal studies have shown that AVP has metabolic effects, including reducing food intake, inducing lipolysis, and promoting muscle regeneration in male mice. Furthermore, AVP is regulated differently in males and females, and affects cognition differently across sexes, a phenomenon called sexual dimorphism. However, it is unknown whether its dimorphism translates to metabolism. Also, findings on AVP metabolic role are inconsistent, possibly due to the opposing effects of AVP at different receptor subtypes, which regulation is still largely unknown. We performed this study to better investigate AVP metabolic role, and explore sex differences. We hypothesized that AVP would be positively associated with BMI, adiposity, and lean mass (acting as a signal of energy availability). We also predicted that relationships between AVP and body composition measures would differ by sex. We used the AVP area under the curve around a standardized meal to better capture repeated measures in response to food intake (that directly impacts energy availability). This also allowed to avoid the possible risk of fluctuating AVP levels due to possible pulsatile secretion. (more…)
Exercise - Fitness, Lifestyle & Health, Weight Research / 03.04.2023

This article is for informational purposes only and is not a substitute for professional medical advice, diagnosis or treatment. Contact a qualified medical professional before engaging in any physical activity,injections,  or making any changes to your diet, medication or lifestyle, We all have those areas on our bodies that tend to ‘show’ fat more easily – areas such as our chins, the backs of our arms and thighs, and of course, our bellies. And no matter how hard we try, we just can’t seem to get rid of them. It seems that no amount of diet and exercise can help us do away with those stubborn pockets of fat. Those unsightly fat pockets are a definite turn-off, even if you're almost at your recommended weight. While it's true that you should love your body regardless of its shape or form – this is the era of body positivity, after all – if you can address those stubborn areas, life would be so much easier – and better. But how do you eliminate those unwanted, stubborn fat pockets with the right diet and exercise once and for all? Let's find out. (more…)
Author Interviews, Diabetes, Karolinski Institute, Pediatrics, Weight Research / 28.02.2023

MedicalResearch.com Interview with: Yuxia Wei | PhD Student Unit of Epidemiology Institute of Environmental Medicine Karolinska Institutet Stockholm | Sweden   MedicalResearch.com: What is the background for this study? Response: Diabetes is traditionally known for having two types (type 1 diabetes and type 2 diabetes). However, it is becoming increasingly clear that diabetes is much more complex than this traditional classification. Several attempts have been made to address this heterogeneity and in 2018, a  Swedish ground-breaking study proposed that there are five distinct subtypes of diabetes in adults. They have been replicated in different populations and it has been shown that there are differences between the subtypes in terms of genetics and risks of complications. Another way of elucidating the relevance of these subtypes is to investigate whether the influence of known risk factors for diabetes is different on different subtypes. Our study is one of the first attempts to address this. We used a study design known as Mendelian randomization, to investigate the influence of childhood obesity on these diabetes subtypes that typically occur after age 35. This work was a collaboration between Karolinska institutet in Stockholm, University of Bristol in the UK and Sun Yat-Sen University in China. (more…)
Author Interviews, Genetic Research, JAMA, Karolinski Institute, Weight Research / 31.01.2023

MedicalResearch.com Interview with: Lisa Dinkler, Ph.D. | Postdoctoral researcher Center for Eating Disorders Innovation (CEDI) Department of Medical Epidemiology and Biostatistics Karolinska Institutet, Stockholm MedicalResearch.com: What is the background for this study? Response: Avoidant restrictive food intake disorder (ARFID) is a relatively recently defined eating disorder. Affected people severely restrict their food intake in terms of total amount or variety. This leads to serious physical, psychological, and social consequences such as weight loss, nutritional deficiencies, and social isolation. Compared to people with other eating disorders – such as anorexia nervosa, bulimia nervosa, and binge-eating disorder – food restriction in people with ARFID is not driven by body dissatisfaction or the desire to lose weight. Despite how serious ARFID is, we still know very little about what causes it – making it difficult to develop effective treatments. We do know that genetic factors contribute significantly to the development of other eating disorders (so-called heritability), but we did not yet know to which degree genetic factors play a role in the development of ARFID. We therefore conducted the first twin study of ARFID, using a sample of ~34,000 Swedish twins including ~700 children with ARFID. (more…)
Author Interviews, Diabetes, Sleep Disorders, Weight Research / 26.09.2022

MedicalResearch.com Interview with: Steven K. Malin, PhD, FACSM (he/him) Associate Professor Department of Kinesiology and Health | School of Arts and Sciences Division of Endocrinology, Metabolism and Nutrition | Robert Wood Johnson Medical School Institute of Translational Medicine and Science New Brunswick, NJ 08901 MedicalResearch.com: What is the background for this study? Response: Type 2 diabetes is a condition where blood glucose (sugar) is elevated in the  blood. This can be problematic as it leads to blood vessel damage and the promotion of cardiovascular disease. Nearly 30 million people  in the U.S. have type 2 diabetes, making it a major public health issue. The cause is not entirely clear, but many, including our team view insulin resistance as a central culprit. Insulin resistance is when the body does not respond well to the hormone insulin. Insulin is vital because it promotes glucose uptake into tissues, like skeletal muscle. Two reasons that are often used to explain the development of insulin resistance include: poor diet (e.g. high sugar and/or high fat coupled with excess calories) and a lack of physical activity. However, more recently, a lack of sleep has been raised as another critical behavioral factor contributing to insulin resistance. Thus, targeting a healthy diet, activity and sleep pattern is thought to prevent the transition from health to insulin resistance and type 2 diabetes. (more…)
Author Interviews, JAMA, Pediatrics, Weight Research / 28.07.2022

MedicalResearch.com Interview with: Amanda Staiano, PhD Associate Professor Director, Pediatric Obesity and Health Behavior Laboratory Pennington Biomedical Research Center Baton Rouge, LA MedicalResearch.com:  What are the main findings? Response: The U.S. government funds the National Health and Nutrition Examination Survey (NHANES), which is an ongoing surveillance study on the health and nutritional status of people living in the U.S. What is special about NHANES is it’s designed to be nationally representative and it uses objective measurements, so we’re more confident that this accurately reflects the health of the country. For this paper, we looked at the most recently released data to see how many children in the U.S. have obesity, meaning they’re above the 95th percentile for height and weight based on their age and sex. We extracted data from 2011 to 2020, which includes nearly 15,000 children and adolescents and is the most recently available data prior to the March 2020 COVID-19 shutdown when NHANES paused. (more…)
Author Interviews, Breast Cancer, JACC, Weight Research / 18.05.2022

MedicalResearch.com Interview with: Dr. Amy Kirkham, PhD Assistant Professor of Clinical Cardiovascular Health Faculty of Kinesiology & Physical Education University of Toronto Affiliate Scientist at Toronto Rehabilitation Institute MedicalResearch.com:  What is the background for this study?  Response: Women who have had a breast cancer diagnosis are at least two-fold and often higher risk of cardiovascular or heart disease compared to women without a history of breast cancer. Older age, higher body mass index, and receipt of chemotherapy treatment that can injure the heart are risk factors for cardiovascular death after a breast cancer diagnosis. Time-restricted eating is a type of intermittent fasting that appears to be easy to follow and to improve some measures of metabolic health but has not been studied in populations with a cancer history. Time-restricted eating simply involves consuming all calorie intake within a specific time window, commonly 8 hours, like between 12 and 8 pm, and then only consuming water or black coffee outside of those hours. We enrolled breast cancer survivors who were aged 60 or older, had an overweight or obese mass index, and were finished chemotherapy treatment in a single-arm trial of time-restricted eating for 8 weeks. We asked participants to restrict their calorie intake between 12 and 8 pm from Monday to Friday with no restrictions on weekend and no further instructions on what to eat. (more…)
Author Interviews, Cleveland Clinic, Diabetes, JACC, Surgical Research, Weight Research / 14.04.2022

MedicalResearch.com Interview with: Amgad Mentias, MD MS FACC FESC Assistant Professor, CCLCM Section of Clinical Cardiology, Heart and Vascular Institute. Cleveland, OH 44195Amgad Mentias, MD MS FACC FESC Assistant Professor, CCLCM Section of Clinical Cardiology, Heart and Vascular Institute. Cleveland, OH 44195  MedicalResearch.com:  What is the background for this study?    Response:  There is evidence that bariatric or weight loss surgery can decrease the risk of heart attack, stroke, and death in young and middle age patients with obesity and diabetes. However, the evidence is less clear for older patients and patients without diabetes. There is also no long-term data on outcomes of bariatric surgery in the Medicare beneficiaries. So, in our study, we aimed to report long-term outcomes of bariatric surgery from a contemporary nationwide cohort from the US, while also looking into outcomes in patients older than 65 years, and patients without type 2 diabetes specifically. (more…)
Author Interviews, Nature, Weight Research / 07.04.2022

MedicalResearch.com Interview with: Lee Roberts PhD Professor and Chair of Molecular Physiology and Metabolism Department of Discovery and Translational Science Leeds Institute of Cardiovascular & Metabolic Medicine School of Medicine University of Leeds MedicalResearch.com:  What is the background for this study?  What are the main findings?  Response: Obesity rates have nearly tripled worldwide since 1975. In 2016, there were more than 650 million adults aged 18 and above with obesity. Obesity can lead to increased fat in the blood which damages tissues and organs, contributing to the development of cardiovascular and metabolic diseases including type 2 diabetes. This elevated blood fat can damage the cellular organelle responsible for making protein, the endoplasmic reticulum, causing the cell to come under stress and potentially resulting in the cell dying. When this occurs in skeletal muscle it can contribute to features of the metabolic syndrome including metabolic dysfunction and insulin resistance. (more…)