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24 Feb Antibody–Drug Conjugate in Refractory Metastatic Triple-Negative Breast Cancer
Posted at 15:09h
in Author Interviews, Breast Cancer, Brigham & Women's - Harvard, Chemotherapy, NEJM
This publication highlights a potential novel approach to treat metastatic triple negative breast cancer and improve clinical outcomes, thereby creating a new treatment paradigm.
24 Feb Not All Polypharmacy for Schizophrenia is Bad
MedicalResearch.com Interview with: Jari Tiihonen, MD, PhD Professor, Department of Clinical Neuroscience Karolinska Institutet Stockholm, Sweden MedicalResearch.com: What is the background for this study? Response: The effectiveness of antipsychotic combination therapy in schizophrenia relapse prevention is controversial, and use of multiple agents is generally believed to impair physical well-being. But...
19 Feb Better Outcomes At Stroke Centers That Do More Clot Removals
In short, there was a 30% increase in the likelihood of good stroke outcomes for every 10 additional annual endovascular stroke treatments per year.
15 Feb Hypofractionated Radiation for Low Risk Prostate Cancer Saves Time and Money
Study results showed that patients were unable to detect any difference in any of their symptoms or quality of life between treatments.
15 Feb Aortic Stenosis Staging Helps Predict TAVR Outcomes
This may raise our awareness that there might be other comorbidities that might be limiting the full benefit of TAVR and to evaluate other strategies that we can do something beyond that
07 Feb Life in the Womb Can Program Future Heart Disease
MedicalResearch.com Interview with: Professor Dino A. Giussani PhD ScD FRCOG Professor of Developmental Cardiovascular Physiology & Medicine Department of Physiology Development & Neuroscience University of Cambridge Director of Studies in Medicine College Lectureship in Medicine ‘1958’ Gonville & Caius College UK MedicalResearch.com: What is the background for this study? What are the main findings? Response:...
21 Jan Breast Cancer Survivors More Likely To Develop Subsequent Blood Cancers
MedicalResearch.com Interview with: Dr. Marie Joelle Jabagi, PharmD, MPH University of Paris Sud, Paris-Saclay University, Paris Health Product Epidemiology Department French National Agency for Medicines and Health Products Safety Saint-Denis, France MedicalResearch.com: What is the background for this study? Response: Secondary hematologic malignant neoplasms that develop months or years after the...
21 Jan Depression May Be a Driver of Alopecia Areata
Alopecia areata can have significant impacts on a patient’s mental health, but sometimes it seems as though mental health might actually be a driver in developing alopecia areata in the first place.
13 Jan Diabetes: Study Find Statins Protect Against Vision Loss
The result showed that statin therapy was associated with reduced risk of diabetic retinopathy
11 Jan Blood Clots Linked to Oral Hormone Replacement for Menopause Symptoms
Posted at 14:42h
in Author Interviews, BMJ, Endocrinology, Heart Disease, Hormone Therapy, Menopause, Thromboembolism
Although hormone replacement therapy medications are generally relatively safe, the background risk of VTE increases with age and with presence of other risk factors.
11 Jan New Intestinal Microbiome Changes After Bariatric Surgery
MedicalResearch.com Interview with: Casey Morrow, Ph.D. Leader of the research team and professor emeritus Department of Cell, Developmental and Integrative Biology University of Alabama at Birmingham MedicalResearch.com: What is the background for this study? Response: The human gastrointestinal tract (GIT) contains several distinct physical environments within the stomach, small intestine...
09 Jan Lumbar Spinal Stenosis: Non-Surgical Options Compared
MedicalResearch.com Interview with: Dr. Michael Schneider DC, PhD Associate Professor School of Health and Rehabilitation Sciences University of Pittsburgh MedicalResearch.com: What is the background for this study? Response: Lumbar spinal stenosis (LSS) is one of the fastest growing problems in the country due to its aging population. One third of...
03 Jan Chronic Kidney Disease: Exome Sequencing Can Help Resolve Some Diagnostic Challenges
MedicalResearch.com Interview with: Emily E. Groopman, B.A Departments of Medicine Hammer Health Sciences, and the Department of Epidemiology Columbia University, New York MedicalResearch.com: What is the background for this study? Response: Exome sequencing (ES), targeted capture of the protein-coding segments of the human genome, is quickly becoming a first-line diagnostic...
15 Dec Dermatologist Discusses Personalized Approach to Skin Cancer Treatment
While Mohs surgery is considered the gold standard when it comes to nonmelanoma skin cancer and excision for melanoma, there are other treatment options.
12 Dec Novel Subtypes in B Progenitor Acute Lymphoblastic Leukemia
Posted at 16:01h
in Author Interviews
MedicalResearch.comInterview with: Zhaohui Gu, PhDPostdoctoral Research Associate St. Jude Children’s Research Hospital, TN MedicalResearch.com: What is the background for this study? What are the main findings? Response:B-progenitor acute lymphoblastic leukemia (B-ALL) is the most common pediatric malignancy and the leading cause of childhood cancer death. B-ALL includes multiple subtypes that are defined...
11 Dec Phase I Study T-cell Bispecific Antibody For Aggressive Non-Hodgkin’s Lymphoma
Posted at 23:08h
in Cancer Research
The preliminary results suggest that CD20-TCB monotherapy have promising clinical activity and may induce durable complete responses in patients with late-line R/R aggressive Non-Hodgkin’s Lymphoma.
11 Dec Data Support Venclexta Combinations As New Treatment Option for AML
Posted at 22:46h
in Author Interviews
Acute myeloid leukemia, is a difficult-to-treat disease and these Venclexta combinations represent an important new treatment option for patients.
05 Dec XARELTO® Associated With a Decreased Risk of Recurrent VTE
XARELTO® was associated with a decreased risk of recurrent VTE with no increase in major bleeding during this time period.
05 Dec ASH18: RNA Sequencing Identifies More Subtypes of Childhood Leukemia
MedicalResearch.com Interview with: Charles G. Mullighan, MBBS (Hons), MSc, MD Member, St. Jude Faculty Co-Leader, Hematological Malignancies Program Medical Director, St. Jude Biorepository William E. Evans Endowed Chair St. Judes Children’s Research Hospital Memphis, TN MedicalResearch.com: What is the background for this study? Response: B-lineage acute lymphoblastic leukemia (B-ALL) is the...
05 Dec RAS Inhibitor Linked to Reduced Heart Failure and Mortality After TAVR
Prescription for a RAS inhibitor after TAVR may be associated with lower mortality and risk for HF readmission.
03 Dec The Medalist Trial: Luspatercept Reduced Transfusion Need in Some Myelodysplastic Syndromes
MedicalResearch.com Interview with: Dr. Alan List MD President and Chief Executive Officer Moffitt Cancer Center Tampa, FL MedicalResearch.com: What is the background for this study? Response: In patients with lower risk Myelodysplastic Syndromes (MDS), which accounts for the vast majority of patients with MDS overall, the most common symptomatic cytopenia is...
03 Dec Alcyone Trial: DaraVMP New Standard for Transplant-Ineligible Newly Diagnosed Multiple Myeloma
DaraVMP is a new standard of care for ND multiple myeloma not eligible for transplant that can be potentially affordable in many countries due to the fact that bortezomib, melphalan and prednisone is not an expensive combination so dara would be the only new and more expensive agent
02 Dec ASH18: CENTAURUS Study Evaluates Dosing Schedule of DARZALEX® (daratumumab) for High Risk Smoldering Multiple Myeloma
Response: The CENTAURUS study was a randomized phase II trial evaluating 3 different dosing schedules of daratumumab for the treatment of smoldering multiple myeloma at intermediate to high risk of progression to active disease
28 Nov CTCA Reports Thousands of Patients Have Had Treatment Based On Precision Biomarkers
MedicalResearch.com Interview with: Ricardo Alvarez MD MSc Medical Director of the Breast Cancer Center Director of Cancer Research Cancer Treatment Centers of America, CTCA Atlanta MedicalResearch.com: What is the background for this study? What are the main findings? Response: “The background of this study comes from five years of experience in...
22 Nov Asthma: Biologic Benralizumab (FASENRA) Reduced Need For Rescue Medication
MedicalResearch.com Interview with: Sean O’Quinn MPH Director, Patient Reported Outcomes AstraZeneca MedicalResearch.com: What is the background for this study? How does benralizumab differ from traditional medications for asthma? Response: FASENRA™ (benralizumab 30mg for subcutaneous injection as add-on maintenance therapy in severe eosinophilic asthma for patients 12 years and older) has...
20 Nov What is Risk of Sexual Transmission of HIV With Treatment-Suppressed Low Viral Load?
Despite the advances in knowledge around HIV transmission, people living with HIV still face considerable stigma and discrimination as a result of their diagnosis.
15 Nov Surgical Menopause Linked To More Insomnia and Sleep Difficulties
MedicalResearch.com Interview with: Sooyeon Suh, PhD Department of Psychology Sungshin University Seoul, Republic of Korea MedicalResearch.com: What is the background for this study? What are the main findings? Response: Women who are going through menopause frequently complain of sleep complaints and depressive symptoms in addition to other typical symptoms such...
14 Nov Advanced Prostate Cancer: Androgen-Receptor Testing May Guide Selection of Treatment
MedicalResearch.com Interview with: Vincenza Conteduca, MD, PhD Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) Srl – IRCCS Meldola , Italy MedicalResearch.com: What is the background for this study? What are the main findings? Response: In our previous publications, we showed that the study of plasma cell-free...