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27 Feb

Posted at 13:34h in ASCO, Author Interviews, Cognitive Issues, Endocrinology, Journal Clinical Oncology, Prostate Cancer, Testosterone
MedicalResearch.com Interview with: Farzin Khosrow-Khavar, M.Sc. Ph.D. Candidate Department of Epidemiology, Biostatistics and Occupational Health, McGill University Center for Clinical Epidemiology – Jewish General Hospital Montreal, QC  MedicalResearch.com: What is the background for this study? What are the main findings? Response: Previous studies have shown an association between androgen deprivation therapy...

24 Feb

Posted at 00:05h in Author Interviews, Breast Cancer, Chemotherapy, Personalized Medicine
MedicalResearch.com Interview with: Eran Andrechek, PhD Associate Professor Department of Physiology Michigan State University East Lansing, MI  MedicalResearch.com: What is the background for this study? Response: Of the various types of breast cancer, triple negative breast cancer (lacking estrogen receptor, progesterone receptor and HER2) has the worst outcome and is...

23 Feb

Posted at 22:39h in Author Interviews, Biomarkers, Genetic Research, PLoS, Prostate Cancer
MedicalResearch.com Interview with: G. Andrés Cisneros, Ph.D. Associate Professor Department of Chemistry Center for Advanced Scientific Computing and Modeling, University of North Texas MedicalResearch.com: What is the background for this study? What are the main findings? Response: The accurate maintenance of DNA is crucial, if DNA damage is not addressed...

16 Feb

Posted at 23:20h in Author Interviews, Sexual Health, Technology
MedicalResearch.com Interview with: Dr. Krychman is Executive Director, President, and CEO of the Southern California Center for Sexual Health and Survivorship Medicine and Associate Clinical Professor at the University of California, Irvine, Department of Obstetrics and Gynecology. He is a Member of the International Society for the Study of Women’s Sexual...

13 Feb

Posted at 23:05h in Author Interviews, Brigham & Women's - Harvard, Cancer Research, Dermatology, Diabetes, Melanoma
MedicalResearch.com Interview with: Bin Zheng, PhD Assistant Professor Cutaneous Biology Research Center Massachusetts General Hospital Harvard Medical School Charlestown, MA 02129  MedicalResearch.com: What is the background for this study? What are the main findings? Response: Melanoma is the most deadly form of skin cancer with more than 75,000 newly diagnosed cases...

09 Feb

Posted at 02:21h in Author Interviews, Cancer Research, Heart Disease, PNAS, UT Southwestern
MedicalResearch.com Interview with: Lawrence Lum, Ph.D. Associate Professor Virginia Murchison Linthicum Scholar in Medical Research UT Southwestern Medical Center MedicalResearch.com: What is the background for this study? What are the main findings? Response: Scarring of the adult heart due to excessive fibrotic responses is common after a heart attack, or...

27 Jan

Posted at 20:28h in Author Interviews, Endocrinology, Pediatrics
MedicalResearch.com Interview with: Adda Grimberg, MD Associate Professor of Pediatrics, Perelman School of Medicine, University of Pennsylvania Scientific Director, Diagnostic and Research Growth Center The Children’s Hospital of Philadelphia Philadelphia, PA 19104 MedicalResearch.com: What is the background for this study? What are the main findings? Response: This study sought to...

21 Jan

Posted at 15:02h in Author Interviews, Heart Disease
MedicalResearch.com Interview with: Dr. Elena Arbelo MD PhD Department of Cardiology, Cardiovascular Institute Hospital Clínic de Barcelona University of Barcelona Barcelona, Spain MedicalResearch.com: What is the background for this study? What are the main findings? Response: Almost 20 years after its first description, catheter ablation is a widely-used treatment strategy...

26 Dec

Posted at 12:26h in AACR, Author Interviews, Biomarkers, Breast Cancer, Chemotherapy
MedicalResearch.com Interview with: Helena Jernström, PhD Associate Professor in Experimental Oncology Study Coordinator for Graduate studies Division of Oncology and Pathology Coordinator of the programmes in statistics and epidemiology for doctoral students at the Medical Faculty, Lund University Division of Oncology and Pathology, Department of Clinical Sciences, Lund Lund University...

23 Dec

Posted at 13:23h in Author Interviews, Cancer Research, Columbia, Genetic Research, Personalized Medicine
MedicalResearch.com Interview with: Dr. Kai Wang Zilkha Neurogenetic Institute, University of Southern California Institute for Genomic Medicine, Columbia University MedicalResearch.com: What is the background for this study? What are the main findings? Response: Cancer is a genetic disease caused by a small number of “driver mutations” in the cancer genome...

17 Dec

Posted at 02:32h in Author Interviews, Heart Disease, JACC, Surgical Research
MedicalResearch.com Interview with: Frederick L. Grover, M. D. Professor, Division of Cardiothoracic Surgery Past Chair, Department of Surgery University of Colorado School of Medicine-Anschutz Medical Campus Aurora, CO Past President, Society of Thoracic Surgeons Vice Chair, Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry MedicalResearch.com: What is...

12 Dec

Posted at 22:58h in Author Interviews, Boehringer Ingelheim, Cancer Research
MedicalResearch.com Interview with: Professor Giorgio V. Scagliotti Chair of the Department of Oncology University of Torino,Italy MedicalResearch.com: What is the background for this study? What are the main findings? Response: LUME-Meso II is an international study designed to evaluate the safety and efficacy of nintedanib plus pemetrexed/cisplatin, followed by nintedanib...

09 Dec

Posted at 12:12h in Author Interviews, Breast Cancer, Chemotherapy, Immunotherapy
MedicalResearch.com Interview with: Vince Giranda, M.D., PH.D. Project Director AbbVie Oncology Development MedicalResearch.com: What is the background for this study? What are the main findings? Response: In this Phase 2 study, called BROCADE 2, veliparib combined with the platinum chemotherapy regimen carboplatin and paclitaxel showed positive trends in overall survival...

08 Dec

Posted at 16:59h in Aging, Author Interviews, Genetic Research, JAMA, Macular Degeneration, Ophthalmology
MedicalResearch.com Interview with: Anneke I. den Hollander, PhD Department of Ophthalmology and Department of Human Genetics Donders Institute for Brain, Cognition, and Behaviour Radboud University Medical Center Nijmegen, the Netherland MedicalResearch.com: What is the background for this study? What are the main findings? Response: Age-related macular degeneration is caused by a combination...

05 Dec

Posted at 22:09h in Author Interviews, Genetic Research, Leukemia
MedicalResearch.com Interview with: Michelle Churchman, PhD Scientific Manager of Charles Mullighan’s laboratory Department of Pathology St Jude Children’s Research Hospital MedicalResearch.com: What is the background for this study? What are the main findings? Response: The role of IKZF1 alterations in the development of B-progenitor acute lymphoblastic leukemia (B-ALL) and their...

23 Nov

Posted at 01:13h in Author Interviews, Breast Cancer, Geriatrics, Radiation Therapy
MedicalResearch.com Interview with: Emily C. Daugherty, MD Upstate Medical University Radiation Oncology Resident, PGY-4 MedicalResearch.com: What is the background for this study? Response: Adjuvant radiation following breast conserving surgery has been well established in the management of early-stage breast cancer as it has been shown to decrease the incidence of...

20 Nov

Posted at 13:03h in Author Interviews, Endocrinology, Hormone Therapy, JCEM, Menopause, Osteoporosis
MedicalResearch.com Interview with: Dr Georgios Papadakis FMH, Médecin InternenMédecin assistant Service d’endocrinologie, diabétologie et métabolisme Lausanne MedicalResearch.com: What is the background for this study? Response: This study was mainly motivated by the absence of available data on the effect of menopausal hormone therapy (MHT) on bone microarchitecture, as well as...

19 Nov

Posted at 21:11h in Author Interviews, Gout, Kidney Disease
MedicalResearch.com Interview with: Gerald D. Levy MD Internal Medicine/Rheumatology Southern California Kaiser Permanente Downey, CA  MedicalResearch.com: What are the main findings of your study? Patients with hyperuricemia and chronic kidney disease (CKD)  improve when serum Uric Acid (sUA) is brought below 6mg/dl with urate lowering therapy. We found a 6% improvement...

09 Nov

Posted at 14:25h in Author Interviews, Breast Cancer, Chemotherapy, JAMA, Karolinski Institute
MedicalResearch.com Interview with: Jonas Bergh M.D, Ph.D. F.R.C.P. (London, UK) Professor of Oncology (Mimi Althainz´donation) Director Strategic Research Program in Cancer Karolinska Institutet Radiumhemmet, Karolinska University Hospital Stockholm, Swede MedicalResearch.com: What is the background for this study? Response: Present standard dosing of chemotherapy is aiming at a similar dose for...

09 Nov

Posted at 00:48h in Author Interviews, Cancer Research, Immunotherapy, Vaccine Studies
MedicalResearch.com Interview with: Leslie Chong Imugene Chief Operating Officer Armadale, Australia   MedicalResearch.com: What is the background for this study? How does HER-Vaxx work? • The technology originates from the Medical University of Vienna, one of Europe’s leading cancer institutes and was identified in 2012 by Dr Axel Hoos (Currently...

21 Oct

Posted at 21:29h in Author Interviews, NEJM, Prostate Cancer
MedicalResearch.com Interview with: Professor Jenny Donovan OBE FMedSci NIHR-SI AcSS FFPHM Director, NIHR CLAHRC West (National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care West) at University Hospitals Bristol NHS Trust Lewins Mead, Bristol Professor of Social Medicine School of Social and Community Medicine University of...

06 Oct

Posted at 21:14h in Author Interviews, Gastrointestinal Disease, Pancreatic
MedicalResearch.com Interview with: Dr. Pouria Jandaghi Functional Genome Analysis, Deutsches Krebsforschungszentrum Heidelberg, Germany Department of Human Genetics, McGill University University and Genome Quebec Innovation Centre Montreal, Canada MedicalResearch.com: What is the background for this study? Response: Although the overall five-year survival of all patients with cancer stands at 63%, for...

23 Sep

Posted at 00:10h in Author Interviews, Breast Cancer, Cancer, Genetic Research, UT Southwestern
MedicalResearch.com Interview with: Roshni Rao, M.D Breast Surgery University of Texas Southwestern MedicalResearch.com: What is the background for this study? What are the main findings? Response: Triple negative breast cancer (TNBC) is characterized by not having estrogen, progesterone, or Her2Neu receptors. Although a less common type, it is aggressive, and leads...

22 Sep

Posted at 11:54h in ASCO, Author Interviews, Cancer Research, Journal Clinical Oncology
MedicalResearch.com Interview with: Darren R. Feldman, MD Medical Oncologist Memorial Sloan Kettering Cancer Center MedicalResearch.com: What is the background for this study? What are the main findings? Response: There is limited knowledge as to why a minority of patients with advanced germ cell tumors are resistant to chemotherapy while the...

20 Sep

Posted at 10:51h in Author Interviews, Genetic Research, Heart Disease, JACC
MedicalResearch.com Interview with: Prof. dr. P. van der Harst Interventional Cardiologist Scientific Director Cardiac Catheterization Laboratory University Medical Center Groningen Groningen The Netherlands MedicalResearch.com: What is the background for this study? What are the main findings? Response: The electrocardiogram harbors important clues for the development and progression of heart diseases....

11 Sep

Posted at 21:03h in Author Interviews, Biomarkers, Cancer Research, Lung Cancer
MedicalResearch.com Interview with: Karen L. Reckamp, M.D. Associate Professor City of Hope Comprehensive Cancer Center Duarte, CA 91010 MedicalResearch.com: What is the background for this study? What are the main findings? Response: • Approximately 60% of patients with non-small cell lung cancer (NSCLC) receiving EGFR tyrosine kinase inhibitors (TKIs) will...

06 Sep

Posted at 11:56h in Author Interviews, Cancer Research, Heart Disease, Pediatrics
MedicalResearch.com Interview with: Steven E. Lipshultz, MD, FAAP, FAHA Schotanus Family Endowed Chair of Pediatrics / Carman and Ann Adams Endowed Chair in Pediatric Research / Professor, Carman and Ann Adams Department of Pediatrics / Professor of Medicine (Cardiology), Oncology, Obstetrics/Gynecology, Molecular Biology/Genetics, Family Medicine/Public Health Sciences, & Pharmacology /Professor...

29 Aug

Posted at 14:58h in Author Interviews, Biomarkers, Cancer Research, Genetic Research, Lancet
MedicalResearch.com Interview with: Dr. Manel Esteller Director of the Epigenetics and Cancer Biology Program (PEBC) Bellvitge Biomedical Research Institute MedicalResearch.com: What is the background for this study? What are the main findings? Response: Cancer of Unknown Primary (CUP) occurs when the patient is diagnosed with a metastasis but the primary...

19 Aug

Posted at 12:38h in Author Interviews, C. difficile, Genetic Research, Infections
MedicalResearch.com Interview with: Charles Darkoh, Ph.D., MS., MSc. Assistant Professor University of Texas Health Science Center at Houston School of Public Health Department of Epidemiology, Human Genetics & Environmental Sciences Center for Infectious Diseases Houston, Texas 77030 MedicalResearch.com: What is the background for this study? What are the main findings?...