Author Interviews, Gastrointestinal Disease, Infections, NEJM, Vaccine Studies / 15.01.2014
Rotavirus Vaccine and Risk of Intussusception
MedicalResearch.com Interview with Eric S. Weintraub, M.P.H.
Epidemiologist at Centers for Disease Control and Prevention
MedicalResearch.com: What are the main findings of the study?
Mr. Weintraub: While current rotavirus vaccines were not associated with intussusception in large pre-licensure trials, recent post-licensure data (from international settings) suggest the possibility of a low risk of intussusception occurrence after receipt of monovalent rotavirus vaccination (RV1). We examined the risk of intussusception following RV1 vaccination in a U.S. population. In this study of more than 200,000 doses of RV1, a slight increased risk of intussusception was observed after vaccination, which should be considered in light of the benefits of preventing rotavirus associated illness.
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