Author Interviews, Brigham & Women's - Harvard, Dermatology, JAMA, Melanoma, Transplantation / 20.01.2016
Transplantation Patients With Skin Cancer: Fewer New Tumors With Sirolimus
More on Dermatology from MedicalResearch.com
MedicalResearch.com Interview with:
Pritesh S. Karia, MPH
Manager-Dermatologic Oncology Research Program
Mohs and Dermatologic Surgery Center
Brigham and Women's Hospital
Boston, MA 02130
Medical Research: What is the background for this study?
Response: Several recent studies have shown a reduced incidence of skin cancer in organ transplant recipients (OTR) treated with sirolimus as first-time therapy and those converted from calcineurin inhibitors to sirolimus. Although cancer formation is one of the main reasons for conversion to sirolimus, studies examining the effect of sirolimus on the risk of subsequent cancer formation in organ transplant recipients who have already been diagnosed with a post-transplant cancer are limited.
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