Author Interviews, Flu - Influenza, NEJM, Pediatrics, Vaccine Studies / 15.12.2013
MedicalResearch.com Interview with: Ghassan Dbaibo, M.D., FAAP Professor and Vice-Chair for Research and Faculty Development Department of Pediatrics and Adolescent Medicine Head, Division of Pediatric Infectious Diseases Director, Center for Infectious Diseases Research Professor, Department of Biochemistry and Molecular Genetics American University of Beirut Beirut, Lebanon MedicalResearch.com: What are the main findings of the study? Dr. Dbaibo:
- 55% efficacy (95% CI 39–67%) for prevention of all influenza
- These results are comparable with other estimates of efficacy and effectiveness for trivalent inactivated flu vaccines in this age group
- 73% efficacy (97.5% CI 47–86%) for prevention of moderate-to-severe influenza
- By preventing moderate-to-severe influenza, vaccination prevented the most clinically consequential outcomes of infection, reducing hospitalisations by 75% and medical visits by 69%.
- Seroprotection rates of more than 95% for each of the four influenza strains in the vaccine
- An acceptable safety and reactogenicity profile (more…)