Manuel Franco MD, PhD Associate Professor Department of Health Sciences, Public Health Unit Universidad de Alcalá Johns Hopkins Bloomberg School of Public Health Adjunct Associate Professor Dept. of Epidemiology firstname.lastname@example.orgMedicalResearch.com: What are the main findings of the study? Dr. Franco: Population wide weight loss of about 5 kg was related with large decreases in diabetes and cardiovascular mortality. On the contrary, Body weight regain was related with an increase in diabetes prevalence, incidence, and mortality, as well as a deceleration in the previously declining rates of cardiovascular death. (more…)
MedicalResearch.com Interview with Stig E. Bojesen Staff specialist, MD, PhD, DMSci Dept. of Clinical Biochemistry, Copenhagen University Hospital Herlev Hospital DK-2730 Herlev Denmark MedicalResearch.com: What are the main findings of the study?Dr. Bojesen: The most interesting findings were the increased risk of early death after cancer by decreasing telomere length – measured even before the cancer disease surfaced in the individual. This association was present even after adjusting for all known markers of adverse prognosis. We did not expect this, but it has important implications for how we might apply this marker in the management of cancer patients. The second - and also important and unexpected finding - was the overall lack of association with risk of cancer, after adjustment for the most common ordinary risk factors like age, gender, smoking and so on. This was in contrast to former meta-analyses and many other smaller studies suggesting increased cancer risk with decreasing telomere length. We could reject this hypothesis with considerable statistical power. (more…)
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