Author Interviews, Endocrinology, JCEM / 16.04.2014
Obstructive Sleep Apnea Raises Risk of Osteoporosis
MedicalResearch.com Interview with:
Kai-Jen Tien, MD
Division of Endocrinology and Metabolism,
Department of Internal Medicine, Chi Mei Medical Center
Assistant Professor, Center of General Education
Chia Nan University of Pharmacy and Science
Tainan, Taiwan
MedicalResearch.com: What are the main findings of the study?
Answer: We conducted the first and largest population-based cohort study to evaluate the association of obstructive sleep apnea (OSA) and osteoporosis in a 6-year follow-up investigation of an Asian population. OSA is characterized by repetitive episodes of apnea/hypopnea and hypoxia in tissue, which might impact the bone metabolism. The results of the study showed that patients with obstructive sleep apnea had 2.74 times the risk of osteoporosis than patents without obstructive sleep apnea after adjustment for the patient`s characteristics and comorbidities. Across all age groups and sex groups, individuals with OSA had higher incidence rate of osteoporosis than individuals without obstructive sleep apnea. Subgroup analysis showed that older patients and female patients had a higher risk for osteoporosis than their younger and male counterparts.
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