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24 Jan The CD6/ALCAM Pathway Promotes Lupus Nephritis via T cell–Mediated Responses
Pathogenic T cells are instrumental in the development and progression of both SLE and Lupus Nephritis.
08 Dec GenXys is Taking the Guesswork out of Prescribing Medications: Is Your Practice Ready for personalized medicine for everyone?
The good news is that modern technology can help the clinicians with accurate prescribing choices.
08 Dec NEJM: Dupilumab for Pediatric Uncontrolled Moderate-to-Severe Asthma
This is the first study to demonstrate that, in children 6-11 years of age, the addition of a biologic( dupilumab) led to improvements in both exacerbations and lung function with an acceptable safety profile.
30 Nov 3 Top Ophthalmological Advances for 2021
Posted at 20:42h
in Author Interviews
Concerning laser vision correction, it is used simultaneously with additional tests to decide on the amount of corneal tissue to be extracted for vision correction. Corneal topography is an effective tool in evaluating corneal abrasions, diseases, deformities, and other corneal issues.
30 Nov The Impact of Social Isolation on Mental Health
Posted at 17:16h
in Mental Health Research
There is a much greater need to increase the number of mental health services and also improve the diversity and depth of the professional mental health community.
23 Nov AHA21: GIRAF Study Results Comparing Anticoagulants and Cognitive Decline in AFib Patients
GIRAF study suggests that for the preservation of cognitive function in patients with atrial fibrillation, adequate treatment is more important than the choice of the drug for anticoagulation.
01 Nov Increased Risk of COVID-19 Deaths and Severe Disease Among Cancer Patients
Posted at 23:22h
in Author Interviews, Cancer Research, COVID -19 Coronavirus, Race/Ethnic Diversity, Radiation Therapy
Importantly, there was a disproportionate burden of COVID morbidity and mortality in patients of Hispanic ethnicity and certain insurance types.
27 Oct Risankizumab Found Ineffective in Severe Asthma
Not only was targeting the IL23 pathway in asthma not beneficial those treated with risankizumab had worse outcomes than those treated with placebo.
21 Sep Surgery: ERAS Protocol Reduced Need for Opioids After Discharge
Posted at 11:20h
in Anesthesiology, Author Interviews, Brigham & Women's - Harvard, Opiods, Surgical Research
ERAS is a multidisciplinary evidence-based perioperative care pathway that was originally designed to hasten recovery, but studies like ours give relevant insights to patients regarding the role of ERAS in reducing opioid prescriptions at hospital discharge.
11 Sep Circadian Body Clock Helps Explain Why Asthma Worsens at Night
Posted at 12:42h
in Asthma, Author Interviews, Brigham & Women's - Harvard, Circadian Rhythm, Occupational Health, PNAS, Pulmonary Disease, Sleep Disorders
Those people who have the worst asthma in general are the ones who suffer from the greatest circadian-induced drops in pulmonary function at night, and also had the greatest changes induced by behaviors, including sleep.
10 Sep Pronounced Regional Disparities in Methadone Availability in the United States
Methadone for the treatment of opioid use disorder (OUD) is exclusively provided by federally regulated opioid treatment programs (OTPs) and has provoked significant community-based and legal controversy regarding its role in the management of this condition.
07 Aug New Approach to Addiction: Diabetes Drug May Curb Cravings and Protect Brain White Matter
We think this research points to a new direction in medication development for the treatment of cocaine use disorder, and possibly other stimulants like methamphetamine.
22 Jul Melanoma: Animal Model Suggests Antibiotics May One Day Be Helpful in Controlling Resistant Disease
I would definitely discourage patients to take antibiotics without the supervision of their treating physician, since it is well known that some antibiotics (belonging to a different pharmacological category) can actually interfere with their treatment.
01 Jul NEJM: First Effective Non-Dietary Treatment of Celiac Disease
We hope that ZED1227 will be generally available to patients with celiac disease who need to “neutralize” minor to moderate amounts of gluten in ill-defined foods, or to patients with complicated (highly gluten sensitive) celiac disease, after a successful completion of these follow up studies.
21 Jun AHA Scientific Statement Highlights Link Between Obstructive Sleep Apnea and Heart Disease
The risk of OSA correlates with body mass index, and obesity remains the one major modifiable risk factor for obstructive sleep apnea.
18 Jun DCISionRT Tool Identifies DCIS Patients With High Risk of Recurrence After Surgery and Radiation
DCISionRT analyzes the biology of a patient’s unique tumor and provides a quantified risk of a woman’s cancer coming back within 10 years-- either as invasive cancer or a DCIS recurrence-- in the form of her Decision Score on a scale of zero to 10.
18 Jun Simple Tool Allows Patients to Stop Hiccups
The main etiology of hiccups is not known, however in some people ,certain things trigger hiccups, such as spicy foods, drinking alcohol or eating fast as well as Cancer Chemotherapy medications.
07 Jun HPV Oropharyngeal Cancer: Reduced Dose ChemoRadiation Linked to Better 5 Year Quality of Life
MedicalResearch.com Interview with: Mai Takahashi MD MPH Mount Sinai Beth Israel – Resident Physician New York, New York MedicalResearch.com: What is the background for this study? Response: The incidence of head and neck cancer had been significantly increasing in North America and Europe driven by Human Papillomavirus-related cancer (HPV OPC)...
02 Jun EU Discusses Increasing Prevention of Melanoma and Non-Melanoma Skin Cancer
Malignant melanoma is the most lethal form of skin cancer.[viii] Historically, melanoma was a rare cancer, but in the past 50 years its incidence has risen faster than almost any other cancer.
19 May Dental Caries: New Approach Breaks Down Harmful Biofilm
In the era of antimicrobial resistance, we may need novel nonbiocidal, precise therapeutic measures to address microbially induced infectious diseases.
16 May DDW21: Semaglutide Augments Weight Loss With Minimal Surgical Procedure
Bariatric surgery remains the gold standard for significant, sustained weight loss and improvement of metabolic outcomes. However, less than 2% of eligible patients pursue this option.
04 May Personalized Radiation Shields May Protect Normal Tissues During Cancer Treatments
Posted at 23:20h
in Author Interviews, Brigham & Women's - Harvard, Cancer Research, Colon Cancer, Radiation Therapy
We used patients’ CT scans to personalize these devices so that they could comfortably and reliably fit to areas that are at risk for damage.
22 Apr Triple Negative Breast Cancer: TRODELVY® (sacituzumab govitecan) Trial Demonstrates Significant Improvement Compared to Standard Chemo
The significant survival benefit seen in the landmark ASCENT study is practice-changing and positions sacituzumab govitecan-hziy as a potential standard of care for pre-treated Triple Negative Breast Cancer.
05 Apr Mechanism of Horrible Itching of Liver Disease Identified in Superficial Skin Cells
The skin can function as a sensory organ through its epithelial cells, keratinocytes, which can assume a quasi-neural function, telling itch neurons what to do by directly signaling to them cell-to-cell.
17 Mar Tips for Managing Anxiety
When someone is anxious, their adrenaline is pumping, and they tend to engage in shallow breathing. Regular abdominal breathing can not only help ease an anxious episode, but it can also help prevent them in the long run.
08 Mar Polygenic Risk Score Identifies Patients with Average LDL Who Could Benefit from Statins
Our study paved the way for the understanding of plaque formation in different polygenic backgrounds.
05 Mar Breast Cancer: Using Blood Brain Barrier-Crossing Stem Cells to Attack Metastases
MedicalResearch.com Interview with: Khalid Shah, MS, PhD Vice Chair of Research, Department of Neurosurgery Director, Center for Stem Cell Therapeutics and Imaging Director, Center for Excellence in Biomedicine Brigham and Women’s Hospital Associate Professor, Harvard Medical School Principal Faculty, Harvard Stem Cell Institute MedicalResearch.com: What is the background for this study?...
03 Mar Alzheimer’s Disease: Animal Model Demonstrates Ability of Novel Enzyme to Decrease Amyloid Plaques
The novel GSM was then tested in a mouse model of early-onset AD, treating the animals either before or shortly after they began to form amyloid plaques.
01 Mar Liver Metastases Treatment
Posted at 15:50h
in Cancer Research
The main benefit of chemoembolization in the treatment for liver metastases is the minimal harm to the patient's health. This is because the procedure causes a local impact on the tumor, namely on the vessels that feed it.