02 May IV Therapy and Vitamin Deficiencies: An Approach to Replenishment
Editor's note: IV Vitamin infusions may have side effects, including allergic reactions and vitamin overdoses. The efficacy of vitamin supplementation in those who are not vitamin deficient is generally not recommended. Please consult you health care provider for specific medical advice before getting vitamin infusions. [caption id="attachment_68298" align="aligncenter" width="233"] Pexels.com image[/caption]
Vitamin and mineral deficiencies are far more prevalent than most individuals realize. Despite widespread consumption of supplements, many people still struggle with deficiencies that remain undiagnosed for years. Often, symptoms such as fatigue, brain fog, and mood disturbances are overlooked or dismissed as a consequence of stress, aging, or lifestyle factors.
Deficiencies in essential nutrients like magnesium, vitamin D, B12, and iron can have profound impacts on energy, immune function, and overall health. However, the challenge lies in the fact that many of these deficiencies are not immediately noticeable, and even when they are, the conventional approach to supplementation is often ineffective.
Shani Vaknine[/caption]
Shani Vaknine, Ph.D. candidate
Brain and Behavioral Sciences
The Hebrew University
MedicalResearch.com: What is the background for this study?
Response: We’ve long known that maternal stress during pregnancy can affect her baby’s development, but the molecular mechanisms behind this remained unclear. In our study, we explored how psychosocial stress experienced by the mother in late pregnancy influences tiny molecular fragments in the newborn’s blood. These fragments, called transfer RNA fragments or tRFs, were considered for many years to be disposable, but have recently been shown to have important biological functions.
Dr. Moyland[/caption]
Cynthia Moylan, MD
Associate Professor of Medicine,
Division of Gastroenterology
Duke University Health System
MedicalResearch.com: What is the background for this study?
Response: Metabolic dysfunction can lead to several health problems including metabolic dysfunction associated steatotic liver disease (MASLD), is driven by different factors, including: a person’s behavioral or lifestyle factors, environmental factors, and genetics. Limited research exists regarding genetic , epigenetic, or other factors that might impact development of metabolic dysfunction and MASLD. Our group has previously shown that alterations in DNA methylation (a type of epigenetic change), identifiable both in liver tissue and in blood, associate with MASLD and its progression to more severe liver disease. Whether DNA methylation that impacts imprinted gene expression also associates with metabolic dysfunction and MASLD risk remains largely unknown.
In this project, we explored imprinted genes: imprinting is a normal process that regulates genes by silencing one parental copy (either the maternal or the paternal) so that only one copy is expressed. Imprinting is an important biological process for development and has a disproportionate impact on disease - in fact, imprinted genes are hypothesized to affect 1-6% of the human genome. We sought to explore how altered DNA methylation of imprint control regions (ICRs) that help ‘control’ these imprinted genes might impact development of metabolic dysfunction in children (and hence potentially even in adults).
Summerlin is known for its clean streets, scenic walking trails, master-planned neighborhoods, and an overall reputation for being one of the safest, most peaceful areas in the Las Vegas Valley.
Unfortunately, that safety doesn’t mean pedestrians are always protected.
Even in a well-designed suburb like Summerlin, where people take pride in the planned beauty of the community, pedestrian accidents happen, and when they do, the effects go way beyond the physical. A 
