05 Oct Beta Blockers Linked To Increased Risk After Non-Cardiac Surgery In Some Hypertensive Patients
Posted at 17:38h
in Author Interviews, Blood Pressure - Hypertension, Heart Disease, JAMA, Surgical Research
MedicalResearch.com Interview with:
Mads E. Jørgensen, MB
Cardiovascular Research Center
Gentofte Hospital
University of Copenhagen, Denmark
Medical Research: What is the background for this study? What are the main findings?
Response: For many years there has been a wide use of beta blockers in the non-cardiac surgery setting with the intent to protect the heart. Within recent years, this field of research has opened up to new studies evaluating in detail which patient subgroups do benefit from this therapy and which may actually be at increased risk. The current study evaluated chronic beta blocker use and risks of perioperative complications in a rather low risk population of patients with hypertension, but without cardiac, kidney or liver disease.
Among 55,000 patients receiving at least two antihypertensive drugs, we found that patients treated with a beta blocker were at increased risks of complications during surgery and 30-day after surgery, compared to patients treated with other antihypertensive drugs only. In various subgroup analyses (by age, gender, diabetes, surgery risk etc.) the findings were consistent although challenged in power.


























