Author Interviews, Cost of Health Care, JAMA, Kidney Disease, Medicare / 11.01.2024

MedicalResearch.com Interview with: Kalli Koukounas, MPH Ph.D. Student, Health Services Research Brown University School of Public Health Providence, RI MedicalResearch.com: What is the background for this study? Response:  On Jan. 1st, 2021, the Centers for Medicare and Medicaid Services (CMS) implemented the End-Stage Renal Disease Treatment Choices (ETC) Model, one of the largest randomized tests of pay-for-performance incentives ever conducted in the US. The goal of the model was to enhance the use of home dialysis and kidney transplant or waitlisting among kidney failure patients in traditional Medicare. The model randomly assigned approximately 30% of US dialysis facilities and nephrologists to receive financial incentives, ranging from bonuses of 4% to penalties of 5%, based on their patients’ use of home dialysis and kidney transplant/waitlisiting. The payment adjustments apply to all Medicare-based reimbursement for dialysis services. Prior research has demonstrated that dialysis facilities that disproportionately serve populations with high social risk have lower use of home dialysis and kidney transplant, raising concerns that these sites may fare poorly in the payment model. Using data released by CMS, we examined the first year of ETC model performance and financial penalties across dialysis facilities, stratified by the measured social risk of the facilities’ incident patients. (more…)
Author Interviews, Neurological Disorders, NYU, Pediatrics / 09.01.2024

MedicalResearch.com Interview with: Laura Gould, MSc, MA, PT Research Scientist SUDC Registry and Research Collaborative Comprehensive Epilepsy Center Department of Neurology NYU Langone Grossman School of Medicine     MedicalResearch.com: What is the background for this study? Response: Sudden Unexplained death in childhood (SUDC) is the unexplained death of a child on or after their 1st birthday that remains unexplained after a comprehensive death investigation. About 400 SUDC occur annually between the ages of 1-18, but more than half occur in toddlers, aged 1-4 years. Since most deaths are sleep related and unwitnessed with unremarkable autopsies, mechanisms of deaths have eluded our understanding. Febrile seizures are common in young children; ~ 3% of US children 6 months to 5 years will experience one. SUDC however has been associated with a 10-fold increase in febrile seizures; our study is the first to implicate them at time of death. The SUDC Registry and Research Collaborative (www.sudcrrc.org) at NYU Langone Health has enrolled over 300 cases of unexplained child death; seven with audiovisual recordings from the child’s bedroom during their last sleep period. More than 80% of the cases enrolled in the registry were children 1-4 years at the time of death. The seven cases with videos were aged 13-27 months with normal development and no pathogenic disease-causing variants by whole exome sequencing. (more…)
Author Interviews, Autism, JAMA, Pediatrics, Technology / 08.01.2024

MedicalResearch.com Interview with: Karen F. Heffler, MD Researcher, Autism Spectrum Disorder Associate Professor, Department of Psychiatry Drexel University College of Medicine Philadelphia, PA MedicalResearch.com: What is the background for this study? children-watching-tv-pexels-photo-4740522 Response: Atypical sensory processing is common in neurodevelopmental disorders, affecting approximately 60% of children with ADHD and up to 90% of children with autism. Sensory symptoms are associated with hyperactivity, restricted/repetitive behavior, irritability, behavioral problems, and emotional dysregulation. Sensory-related meltdowns and symptoms can be very disruptive to family-life, interfere with family participation in community events and are associated with increased caregiver stress. Prior to this study there was little understanding of potential risk factors for atypical sensory processing. The researchers used data from the National Children’s Study to determine the association between early-life screen time and sensory processing outcomes among toddlers. (more…)
Abuse and Neglect, Author Interviews, Gender Differences, Genetic Research, Science, University of Michigan / 05.01.2024

MedicalResearch.com Interview with: Jianzhi "George" ZhangMarshall W. Nirenberg Collegiate ProfessorDepartment of Ecology and Evolutionary BiologyUniversity of MichiganAnn Arbor, MI 48109-1085 MedicalResearch.com: What is the background for this study? Response: A few percent of humans perform same-sex sexual behavior (SSB), a trait that is partially heritable. Because SSB leads to fewer children, the stable maintenance of SSB-associated alleles in populations has been a long-standing Darwinian paradox. A number of hypotheses have been proposed to resolve this paradox, but most of them lack clear empirical evidence. One version of the antagonistic pleiotropy hypothesis posits that SSB-associated alleles are subject to heterosexual advantage. Specifically, it was found that SSB-associated alleles are associated with more sexual partners when in heterosexuals (individuals of exclusive opposite-sex sexual behavior), which could lead to more offspring, potentially compensating the reduced reproduction of SSB individuals. While the above mechanism has likely worked in premodern societies, our recent study (PNAS 2023) found that it is no longer working in the modern United Kingdom, because the widespread use of contraception has decoupled the number of offspring from the number of sexual partners in heterosexuals. (more…)
Nursing / 04.01.2024

When you think of nursing--the classic image of a caregiver attending to physical wounds or administering medicine might come to mind. However, modern healthcare is much like a rich tapestry, threaded with various specialized practices, and nursing has evolved dramatically. Right now, in hospitals and clinics across the world, there's a quiet revolution that's changing the face of healthcare. Nurses are no longer just hands-on with patients--they're expanding into dynamic roles that stretch the very fabric of traditional nursing. Informatics nursing, genetics nursing, and faith community nursing are just some examples of these cutting-edge fields.
The Digital Pulse of Healthcare: Informatics Nursing
health-care-stethoscopeIn today's fast-paced medical scene, have you heard about the tech-savvy guardians of health information? Say hello to informatics nurses. These professionals stand at the crossroads where nursing, computer know-how, and data crunching meet. They're the folks who make sure patient info is spot-on, easy to get to, and as safe as a treasure in a vault. But it's not just about keeping records; they're all about making the day-to-day in hospitals and clinics run smoother. With their expertise, every piece of vital data is organized and used the right way to help the medical team do their thing efficiently.
But what do these nurses do when they're up to their elbows in all that information? They're not hidden away in some server room--they're right in the heart of healthcare, juggling the human touch with high tech. Informatics nurses are the key link between those living, breathing folks in hospital beds and the cold, hard data stored in computers. They make sense of the numbers and charts so that your nurse or doc can craft the perfect care plan, tailored just for you. They're like translators making sure nothing gets lost in translation from human to machine and back again, guaranteeing that every patient gets the right care at the right time.
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Author Interviews, JAMA, Kidney Disease, Salt-Sodium / 03.01.2024

MedicalResearch.com Interview with: Lu Qi, MD, PhD, FAHA Interim Chair, Department of Epidemiolog HCA Regents Distinguished Chair and Professor Tulane University School of Public Health and Tropical Medicine Director, Tulane University Obesity Research Center Director, Tulane Personalized Health Institute New Orleans, LA 70112 MedicalResearch.com: What is the background for this study? Response: Adding salt to foods is a behavior reflecting long-term preference to salty diets. High sodium intake is a major risk factor for chronic kidney disease. In our previous studies, we have found that adding salt to foods at the table is related to various disorders including cardiovascular diseases, diabetes, and mortality.  (more…)
Author Interviews, Gender Differences / 03.01.2024

MedicalResearch.com Interview with: Christian Carbe, PhD Department of Medical Educatio Geisinger Commonwealth School of Medicine Scranton, PA 18509   MedicalResearch.com: What is the background for this study? Response: Transgender patients often experience pronounced healthcare disparities compared to their cisgender counterparts. Disparities in the treatment of transgender patients resulting from deficiencies in cultural competency perpetuate poor health outcomes, such as suicide, substance misuse, depression, harassment, and victimization. Individuals within the transgender community often face systemic barriers within the medical field, including a lack of comprehensive access to health insurance, discrimination from providers, and incompetent provider training in transgender-specific health needs. This report evaluated the changes in knowledge, attitudes, and beliefs of the psychosocial and medical needs of the transgender community among first-year undergraduate medical students that attended the Northeastern Pennsylvania Trans Health Conference. Our broader goal is to develop and refine longitudinal interventions to improve skills and sensitivity of future physicians to provide compassionate and competent gender diverse and transgender healthcare. (more…)
Technology / 27.12.2023

 Imagine you're facing a medical emergency and every second counts. In times like these, help needs to come fast, and it needs to know exactly what it's dealing with. This is where AI chatbots, the unsung heroes equipped with artificial intelligence, step in. Picture them as the ever-ready digital responders who jump into action when a health crisis occurs. They're designed to collect critical information, provide immediate guidance, and even soothe frayed nerves while human help is on the way. When someone's heart is pounding with fear and uncertainty, these chatbots offer a calming voice of reason, laying out clear instructions that could be lifesaving.
When Seconds Feel Like Hours
In a heart-clenching moment, punching in a phone number and waiting for a human operator can feel like an eternity. With AI chatbots, the response is virtually instant. They don’t get flustered; they stay cool as a cucumber, asking all the right questions to figure out what's wrong. With every passing second precious, these chatbots can guide a person suffering from symptoms to take potentially life-preserving actions. From administering CPR to identifying the signs of a stroke, they're programmed to help even before medics arrive on the scene, turning bystanders into first responders armed with information and confidence.
Note:  Please don't let using AI or Chatbots stop you from calling 911!
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Mental Health Research, Social Issues / 26.12.2023

In the fast-paced, interconnected world we now live in, the prevalence of burnout has become a concerning reality for many. The term was first coined in the 1970s to describe the chronic workplace stress that led to physical and emotional exhaustion. Since then, if you are feeling run down and exhausted you may well be yet another victim of modern-day fatigue. Here is a look at the nuances of burnout and some key factors contributing to this pervasive problem. Burnout goes beyond the workplace While burnout traditionally has its roots in a professional workplace setting, modern-day pressures means that the phenomenon now extends beyond the confines of the workplace. Burnout now encompasses a holistic exhaustion that permeates various aspects of life. These include personal relationships, social interactions, and even leisure activities. We have even reached a point where The World Health Organization (WHO) officially recognized burnout as a syndrome in the International Classification of Diseases, emphasizing its impact on overall well-being. (more…)
Author Interviews / 23.12.2023

Being a family caretaker is a labor of affection and a big duty, regardless of whether you are looking for your parents, spouse, or any other senior loved one. You must have the information and resources needed to provide the finest treatment possible in order to carry out such a vital responsibility. An elderly adult's ability to maintain excellent health depends on much more than just prescription drugs and medical care. If you want those closest to you to grow old at ease, independently, and vivaciously, here are the top 5 tips to go along with it.
  1. Encourage periodic tests and check-ups for seniors
Maintaining your elderly parents' well-being and averting probable problems requires routine tests and examinations. Evaluations help identify common persistent illnesses including diabetes, hypertension, and high cholesterol as well as serious illnesses like breast or colorectal cancer. If the elderly person has a chronic condition, monitoring is crucial to preventing and minimizing the consequences of deteriorating symptoms and financial and medical challenges. As It might be difficult for our senior loved ones to remember to get periodic tests done, a compelling senior home care can help them promote active participation, provide transportation, and more. (more…)
Author Interviews / 20.12.2023

MedicalResearch.com Interview with: Amy Kennalley, MBS First Year Medical Student Department of Medical Education Geisinger Commonwealth School of Medicine MedicalResearch.com: What is the background for this study? Response:   Opioid use disorder (OUD) is a major public health crisis in the United States. Despite the availability of effective treatments, including the medication-assisted treatment (MAT) with methadone, many individuals with OUD do not receive the care they need. Over the COVID-19 pandemic, there were several policy changes related to take-home doses of methadone, which may have impacted access to this lifesaving medication. The Drug Enforcement Administration's (DEA)'s Automated Reports and Consolidated Ordering System (ARCOS) is a database that tracks the distribution of controlled substances, including methadone distributed to opioid treatment programs (OTPs). This data can be used to assess trends in methadone distribution over time. Additionally, the Medicaid State Drug Utilization Data (SDUD) database provides comprehensive information on methadone prescribing to Medicaid patients. By analyzing data from both ARCOS and SDUD, we aimed to provide a comprehensive picture of methadone distribution for OUD treatment in the United States. These findings1 are important because drug overdose deaths, primarily involving opioids, increased substantially (49%) from 2019 (70,980) to 2021 (~106,000).2 (more…)
Author Interviews, Brigham & Women's - Harvard, Dental Research, JAMA, Respiratory / 18.12.2023

MedicalResearch.com Interview with: Michael Klompas MD, MPH, FIDSA, FSHEA Hospital Epidemiologist Brigham and Women’s Hospital Professor of Medicine and Population Medicine Harvard Medical School and Harvard Pilgrim Health Care Institute MedicalResearch.com: What is the background for this study? Can teeth be safely brush in patients who are comatose, intubated or have NG tubes? Response: Pneumonia is thought to occur when secretions from the mouth get into the lungs.  Since there are many microbes in the mouth, there’s a risk that secretions from the mouth that get into the lungs will lead to pneumonia.  Toothbrushing may lower this risk by decreasing the quantity of microbes in the mouth. It is indeed safe and appropriate to brush the teeth of someone who is comatose, intubated, or who has an NG tube.  Indeed, our study found that the benefits of toothbrushing were clearest for patients receiving mechanical ventilation. (more…)
Author Interviews, Infections, NYU / 14.12.2023

MedicalResearch.com Interview with: Angélica Cifuentes Kottkamp, MD Assistant Professor of Medicine NYU Grossman School of Medicine Associate Program Director Infectious Diseases & Immunology Fellowship Associate Director for Research & Diversity NYU Langone Vaccine Center & VTEU Attending Physician H+H Bellevue Virology Clinic Division of Infectious Diseases & Immunology NYU Grossman School of Medicine MedicalResearch.com: What is the background for this study? How does the JYNNEOS vaccine differ from the smallpox vaccine? Response: JYNNEOS vaccine is a smallpox vaccine that was repurposed for Mpox given the similarities between the two viruses (smallpox and mpox). The vaccine (JYNNEOS) had been studied in people without HIV therefore there was a gap in knowledge in how this vaccine, especially the small dose (intradermal dose), would work in patients with HIV. These patients resulted to be the most affected by the mpox outbreak suffering the worse outcomes of the disease with the highest death rates. (more…)
Author Interviews, Moderna, NEJM, Pharmaceutical Companies, Respiratory, Vaccine Studies / 13.12.2023

MedicalResearch.com Interview with: Eleanor Wilson, M.D Moderna, 200 Technology Sq. Cambridge, MA 02139 MedicalResearch.com: What is the background for this study? What are the main findings and side effects (if any)? Response: The ConquerRSV trial is a randomized, double-blind, placebo-controlled study of approximately 37,000 adults 60 years or older in 22 countries. The primary efficacy endpoints were based on two definitions of RSV-associated lower respiratory tract disease (RSV-LRTD) defined as either two or more symptoms, or three or more symptoms of disease. Vaccine efficacy was 83.7% (95.88% confidence interval [CI], 66.0 to 92.2) against RSV-associated lower respiratory tract disease with at least two signs or symptoms and 82.4% (96.36% CI, 34.8 to 95.3) against the disease with at least three signs or symptoms. Most adverse reactions were mild to moderate in severity and included injection site pain, fatigue, headache, myalgia, and arthralgia. (more…)
Author Interviews, Technology / 13.12.2023

MedicalResearch.com Interview with: Prof. Enomoto, Masaru Department of Hepatology Graduate School of Medicine Osaka Metropolitan University Osaka, Japan MedicalResearch.com: What is the background for this study? Response: This research was conceived out of the use of generative AI drawing upon past experience in selecting a large amount of literature over an extended amount of time. In recent years, generative AI, such as ChatGPT, has gained attention and is being used in various fields, including information gathering and idea generation. In the medical field in particular, it is challenging to gather pertinent data as the volume of information proliferates on a daily basis, so there is a need to improve the efficiency of information collection. (more…)
Author Interviews, Hematology, Pain Research, Pediatrics / 10.12.2023

MedicalResearch.com Interview with: David Brousseau, MD, MS Chair of Pediatrics Nemours Children’s Health, Delaware and the Sidney Kimmel Medical College at Thomas Jefferson University  MedicalResearch.com: What is the background for this study? Response: Sickle cell disease (SCD) is an inherited red blood cell disorder – the most common genetic disorder in the United States, affecting about 100,000 Americans (1 of every 365 Black births and 1 of every 16,3000 Hispanic-American births) (source: CDC). Pain is its most common symptom. Patients may experience acute or chronic pain or both. Acute episodes of pain, or pain crises, can vary in duration and severity. Many are treated at home; however when the pain is excruciating and cannot be treated at home, they lead to Emergency Department (ED) visits and even hospitalization. Reducing pain through prompt administration of pain medication in the ED is a core principle of national guidelines for SCD care. However, little data exists on how pain scores and changes in pain scores in the ED are associated with the patient’s disposition and the odds of a return visit. (more…)
Author Interviews, Cannabis, Medical Imaging, Pulmonary Disease / 10.12.2023

MedicalResearch.com Interview with: Jessie Kang, MD, FRCPC Assistant professor Department of Diagnostic Radiology Faculty of Medicine Dalhousie University   MedicalResearch.com: What is the background for this study?
  • Marijuana is the most widely used illicit psychoactive substance in the world.
  • Use has increased in Canada since legalization of non-medical marijuana in 2018.
  • It is commonly believed that smoking marijuana is not harmful to the lungs. There is an abundance of established research that identifies the harms of cigarette smoking. In contrast, very little is known about the effects of marijuana smoking, and even less research has been done on the combined effects of smoking marijuana and cigarettes.
To determine the effects of marijuana and cigarette smoking, we examined the chest CT images of four patient groups: non-smokers, cigarette smokers, marijuana smokers, and combined marijuana and cigarette smokers. Marijuana smokers included in the study had smoked marijuana at least four times a month for two years. Patients who ingested marijuana via edibles or oral drops were excluded from the study. (more…)
Author Interviews, Cost of Health Care, Pharmacology / 09.12.2023

MedicalResearch.com Interview with: Joseph T. DiPiro, Pharm.D Associate Vice President, Faculty Affairs Virginia Commonwealth University Dr. DiPiro is an editor for Pharmacotherapy: A Pathophysiologic Approach MedicalResearch.com: What is the background for this study? Response: The ASHP/ASHP Foundation Pharmacy Forecast Report is constructed from a survey of health-system pharmacy leaders who were asked to rate the likelihood of events, scenarios, and trends occurring in the next five years. The purpose is for health-system pharmacists and pharmacy leaders to inform their strategic planning efforts. The Pharmacy Forecast is not intended to predict future events. Rather, the report is intended to be a provocative stimulant for the thinking, discussion, and planning that must take place in every health system. Leaders must be informed of potential developments to help position their organizations to care for patients, enhance population health, and improve medication outcomes. (more…)
Author Interviews, Cancer Research, Case Western, Colon Cancer, JAMA / 07.12.2023

MedicalResearch.com Interview with: Nathan A. Berger, M.D. Distinguished University ProfessorHanna-Payne Professor of Experimental MedicineProfessor of Medicine, Biochemistry, Oncology and GeneticsDirector, Center for Science, Health and SocietyCase Western Reserve University School of Medicine   Rong Xu, PhD Professor, Biomedical Informatics Director, Center for Artificial Intelligence in Drug Discovery Case Western Reserve University School of Medicine     MedicalResearch.com: What is the background for this study? Response: 75% of the US Population has overweight or obesity and 15% has Type 2 Diabetes. Both overweight/obesity and diabetes promote increased incidence and worse prognosis of colorectal cancer. The new GLP1RA drug class are rapidly becoming the most effective treatment for both diabetes and overweight/obesity. By controlling diabetes and overweight/obesity, we hypothesized that the GLP1RAs might be effective at reducing incidence of colorectal cancer. (more…)
Author Interviews, Brigham & Women's - Harvard, Lancet, Pediatrics, Vitamin D / 05.12.2023

MedicalResearch.com Interview with: Dr Ganmaa Davaasambuu MD PhD Associate Professor Harvard T.H. Chan School of Public Health MedicalResearch.com: What is the background for this study? Response: The crucial role of vitamin D in facilitating calcium absorption from the diet and promoting calcium deposition in bones (known as 'mineralization') has been a long-established understanding. Furthermore, some observational studies have reported an association between low vitamin D levels and a heightened risk of bone fractures in children. This raised the possibility that vitamin D supplements could potentially play a role in decreasing fracture risk in children with initially low baseline levels. However, clinical trials assessing the causal link between low vitamin D status and reduced fracture risk were necessary, and such trials had not been conducted before. (more…)
Dental Research / 29.11.2023

So, you've probably heard about ultrasonic tooth cleaners, right? They're like the new kids on the block in the world of dental hygiene. These gadgets use high-frequency sound waves – we're talking ultrasonic vibrations – to gently yet effectively break down and remove all sorts of nasties from your teeth: plaque, tartar, the works. The cool part? They do this without being harsh on your gums or enamel. This is key because, let’s face it, no one wants to trade in tartar for tooth sensitivity. It’s about getting your pearly whites clean without the downsides of traditional scraping tools that sometimes feel like a DIY project gone wrong in your mouth.

Why Ultrasonic Cleaners Could Be Your Teeth's New Best Friends

dental-health-pexels-photo-3706542
Now, why are these ultrasonic wonders good news for your chompers? Well, think about the usual suspects that dentists always warn us about – plaque and tartar. They're not just cosmetic issues; they're like the bad guys plotting against your oral health. Ultrasonic tooth cleaners step in as the superheroes, targeting these troublemakers with precision. This means less plaque and tartar, which in turn means a lower risk of gum disease and cavities. It’s a domino effect, really. Plus, these cleaners often reach where regular brushes can't, like those sneaky spots between your teeth and along your gum line. So, you’re not just cleaning; you're doing a deep clean every time.

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Alzheimer's - Dementia, Author Interviews, Weight Research / 28.11.2023

MedicalResearch.com Interview with:

Mahsa Dolatshahi, M.D., M.P.H. Post-doctoral research fellow Mallinckrodt Institute of Radiology (MIR) Washington University School of Medicine St. Louis MedicalResearch.com: What is the background for this study? Response: Obesity at midlife is recognized as a risk factor for developing Alzheimer disease decades afterwards. However, body mass index on its own does not adequately represent the risks associated with obesity. In this study, we went beyond BMI and considered anatomical distribution of body fat, including the metabolically active visceral fat in the belly, and showed its association with Alzheimer pathology in the form of amyloid proteins. In addition, visceral fat along with obesity and insulin resistance were associated with thinning of brain cortex, as early as midlife. (more…)
Dental Research, Nutrition / 25.11.2023

If you're setting your sights on giving your gums the royal treatment, you're on the right track. You want to buddy up with foods that are friends with your gums. Crunchy greens, like celery and spinach, are packed with gum-loving vitamins and minerals. Noshing on cheese and yogurt isn't just good for your bones; it also helps buffer the acids in your mouth, keeping your gums happy. Why's this a big deal? Well, your gums are the unsung heroes holding your teeth in place, and keeping them healthy is key to making sure your smile stays put for the long run.

Foods to Give a Wide Berth

Now, on to the munchies that your gums wish they could ghost. Sugary snacks and acidic eats like citrus and tomatoes might taste the bomb, but they're no pals to your gums. They invite bacteria to the party, and not the good kind. These guys get down to business, breaking down your gum tissue and causing inflammation. If you're fond of a smoke or a cheeky glass of wine, you might want to rethink that too. Anything that dries out your mouth is basically giving your gums a hard time. Skipping these is critical because, once gum disease checks in, it can be a hassle to show it the door.
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Addiction / 25.11.2023

Addiction is a part of modern life. Some people have addictions that are regarded as minor and not particularly dangerous. Caffeine addiction is widespread, for instance. Other individuals become addicted to something like drugs or alcohol, though. Addiction therapy in Houston may be appropriate if you live there and feel your life is slipping out of your control. If you live elsewhere, you must look for inpatient or outpatient facilities close to you. Some people compare addiction to an anchor that weighs you down. We will talk about why that is an apt comparison right now. What Addiction Does to Your Spirit Anchors are things that incapacitate you, and many people who have a habit that is getting out of control feel that weight every day. It impacts you in many ways, but the spiritual exhaustion an addict feels might be the worst thing that happens to them. When you look at an addict, you might see what their addiction is doing to them physically, but what it is doing to them mentally and psychologically is often just as evident. They may slump as though they’re literally carrying something heavy on their shoulders. This is because they often have to lie and hide their addiction or the extent of it from family members, friends, and coworkers. There’s no way that can be anything but exhausting. (more…)
Aging, Author Interviews, Frailty, Infections / 18.11.2023

MedicalResearch.com Interview with: Hira Mohyuddin, PGY-2 Psychiatry Residency Training Program The George Washington University MedicalResearch.com: What is the background for this study? Response: Frailty has become increasingly significant as the global population grows older, as this syndrome is linked with a higher mortality and morbidity in aging. Causes contributing to frailty are poorly understood, but it seems that the role of inflammation is very likely. While other chronic infections were shown to precipitate and perpetuate inflammation that contributes to the development of frailty, no prior study has previously focused on possible links between Toxoplasma gondii and geriatric frailty. Benefiting from a collaboration with Spanish and Portuguese researchers, we have now tested, for the first time to our knowledge, this possible association. (more…)
Author Interviews, Brigham & Women's - Harvard, Gastrointestinal Disease, Obstructive Sleep Apnea, Technology / 18.11.2023

MedicalResearch.com Interview with: Giovanni Traverso MD PhD Karl Van Tassel (1925) Career Development Professor Department of Mechanical Engineering Koch Institute of Integrative Cancer Research Division of Gastroenterology Brigham and Women’s Hospital Harvard Medical School, Boston, MA, USA   MedicalResearch.com: What is the background for this study? Response: I think its always important to acknowledge that this is a big team effort.  We have the teams from MIT, Celero Systems, West Virgnia University (WVU) and Brigham and Women’s Hospital (BWH) all working together on this.   For this study, Celero prototyped the devices that we tested in pre-clinical (Swine) models and in a first-in-human study with the team at WVU. Our lab focuses on the development of ingestible devices for drug delivery and sensing and these have informed the development of these efforts as you can see. MedicalResearch.com: What types of vital signs are measurable in this fashion? Response: Heart rate and respiratory rate. (more…)
Author Interviews, Cancer Research, Cost of Health Care, JAMA, Pharmacology / 17.11.2023

MedicalResearch.com Interview with: Lisa-Marie Smale, PharmD PhD Candidate Clinical Pharmacy Radboud University Medical Center Department of Pharmacy Nijmegen, the Netherlands Lisa-Marie Smale, PharmDPhD Candidate Clinical PharmacyRadboud University Medical CenterDepartment of PharmacyNijmegen, the Netherlands   MedicalResearch.com: What is the background for this study? Response: Cancer drugs are not always fully used by patients, while these drugs are mostly expensive and environmentally damaging, both in production and (waste) disposal. Therefore we investigated whether unused drugs of patients can be collected, verified of quality by a pharmacy, to be redispensed to other patients instead of being disposed of. We were interested whether such an approach ultimately leads to lower environmental impacts and costs. (more…)