Author Interviews, Diabetes, Diabetes Care, Johns Hopkins / 21.11.2013
MedicalResearch.com Interview with: Caleb Alexander, MD, MS Department of Epidemiology, Bloomberg School of Public Health Center for Drug Safety and Effectiveness Johns Hopkins Bloomberg School of Public Health Division of General Internal Medicine, Johns Hopkins Medicine, Baltimore, Maryland MedicalResearch.com: What are the main findings of the study? Dr. Alexander:
- There have been large shifts in the types of treatments used to treat Type 2 diabetes during the past decade in the United States.
- We document large declines in the use of glitazones and sulfonylureas and important increases in the use of the newer DPP-4 inhibitors and GLP-1 agonists.
- We also found large shifts in the types of insulins used, with substantial reductions in the use of regular and intermediate insulins, and large increases in the use of long-acting and ultra short-acting therapies.
- Costs have increased significantly over the past 5 years, driven primarily by insulin and DPP-4 inhibitors
- All of these changes notwithstanding, biguanides continue to remain a mainstay of therapy. (more…)