Dr. Chen[/caption]
Yingjia Chen, M.Sc, MPH, Ph.D.
Postdoctoral Fellow
University of California, San Francisco
MedicalResearch.com: What is the background for this study?
Response: Both colon cancer and dementia are prevalent among the elderly and have a high risk of co-occurrence. Previous studies found that patients with dementia were treated less aggressively. In this study, we hypothesized that presence of pre-existing dementia was associated with worse survival for stage III colon cancer patients, and that post-operative chemotherapy was on the causal pathway.
Ben-Gurion University of the Negev student researcher Shir Kashi interacts with robotic arm as part of her research in personalizing human-robot interactions to develop an interactive movement protocol for rehabilitation.[/caption]
Shelly Levy-Tzedek, PhD
Head of the Cognition, Aging and Rehabilitation Lab
Faculty of Health Sciences, Dept. of Physical Therapy
& The Zlotowski Center for Neuroscience
The Ben Gurion University
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Following brain injury, patients who need to practice their physical therapy exercises at home. Many don’t practice enough or at all at home, and so we are designing robot companions to encourage them to practice and to track their progress. This study is a first step towards this goal. Here, we studied how people played a leader-follower mirror game with a robotic arm, where a person and robot took turns following each other's joint movements patterns. When the robotic arm was leading, it performed movements that were either sharp, like dribbling a ball, or smooth, like tracing a circle.
Dr. Wolfson[/caption]
Julia Wolfson, PhD MPP
Assistant Professor
Department of Health Management and Policy
Department of Nutritional Sciences
University of Michigan School of Public Health
Ann Arbor, MI 48109
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Over the past several years, Large chain restaurants in the United States have made some progress in introducing new lower calorie items on their menus. Since 2012, calories of items consistently on restaurant menus in all years have not significantly change. In this study, we examined the sodium content of restaurant menu items among 66 of the 100 largest restaurants in the US. We examined sodium content among items on the menu in all years (2012-2016) and among newly introduced items in 2013, 2014, 2015 and 2016 compared to items on the menu in 2012 only.
We found that sodium content of menu items on the menu in all years did not change, but that restaurants were introducing new, lower sodium menu items. However, sodium content of restaurant menu items remains high. This is important because diets high in sodium are associated with serious adverse health outcomes including hypertension, stroke and cardiovascular disease.
Donna Cryer JD[/caption]
Donna R. Cryer, JD
Dr. Chey[/caption]
William D. Chey, M.D., F.A.C.G.
Timothy T. Nostrant Professor of Gastroenterology & Nutrition
Director, Digestive Disorders Nutrition & Lifestyle Program
Michigan Medicine
Ann Arbor, Michigan
MedicalResearch.com: What is the background for this study?
Response: Functional Dyspepsia (FD) has been characterized as recurring indigestion with no known organic cause and is an area of high unmet medical need. This medical condition, which is non-life threatening, can have a significant impact on an individual’s quality of life. It remains poorly recognized and presents a significant management challenge for providers and patients.
Gastrointestinal symptoms can include epigastric pain or discomfort, inability to finish a normal-sized meal, heaviness, pressure, nausea, bloating and belching.
Currently, there are no FDA-approved drugs for FD. Off-label medications are used to treat the condition and patient dissatisfaction remains high.[1]
In a real-world, observational study, called FDACT™ (Functional Dyspepsia Adherence and Compliance Trial), we analyzed information on the frequency of FD symptoms, daily consumption of capsules, onset of action, improvement in FD symptoms, quality of life and patient satisfaction among 600 patients who took FDgard®, a nonprescription medical food specially formulated for the dietary management of FD.
Serge Horbach[/caption]
Serge Horbach MSc
Institute for Science in Society
Radboud University Nijmegen
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Since the late 60s, researchers have pointed to issues in biomedical research stemming from the misidentification of cells. Starting with controversy around HeLa cells, researchers became aware of cells invading other cell cultures. Currently, 488 cell lines have become mixed up with the wrong cells, still often HeLa cells. This leads to errors in reporting research. For example, some research papers have reported results for "lung cancer cells" that turned out to be liver cancer cells, or even mouse cells.
We wanted to know what happened to past research and set out to estimate the number of scientific publications affected by misidentified cells. By tracing misidentified cells of the ICLAC database in Web of Science, we found 32.755 contaminated publications, or 0,8% of all literature in cell biology. These articles are cited by at least 500.000 other publications.
More worryingly, it turned out that this problem is highly stubborn. Currently, still a few dozen new articles are published every month reporting on other cells than were actually used, leading to a total of 1200 each year. And this number is not decreasing, in spite of a database of misidentified cells, of genetic testing availability, requirements by some prominent journals, or attention for the problem in the literature. We were also able to establish that this is not just a problem for newly emergent countries in the international research community, but also for countries with well-establishments research traditions. In spite of great efforts, the problem of cell misidentification is not at all solved.
Dr. Garg[/caption]
Parveen K. Garg, MD, MPH
Assistant Professor of Clinical Medicine
Keck Hospital of USC
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Atrial fibrillation is the most commonly presenting cardiac arrhythmia in clinical practice, affecting over 2 million people in the United States. This arrhythmia accounts for up to 15% of all strokes and annual costs for AF treatment are estimated at over 6.5 billion dollars. Despite the growing public health challenge that AF poses, effective prevention strategies are lacking. In 2010, the American Heart Association identified metrics of ideal cardiovascular health known as Life’s Simple 7 to target for the primary prevention of cardiovascular disease. We wanted to determine whether adherence to these health metrics helps prevent atrial fibrillation as well.
Therefore, we examined the association between the Life’s Simple 7 (LS7) and incident atrial fibrillation in the REasons for Geographic And Ethnic Differences in Stroke (REGARDS) study. We found that individuals in this study with optimal cardiovascular health (high adherence to LS7 metrics) had an over 30% lower risk of developing atrial fibrillation compared to those with inadequate cardiovascular health (low adherence to LS7 metrics). We also observed that even minor improvements in adherence to the LS7 (increase in total score by 1-point) were associated with a 5% lower risk of atrial fibrillation.
Dr. Yang[/caption]
Jingzhen (Ginger) Yang, PhD, MPH
Principal Investigator
Associate Professor, Center for Injury Research and Policy
The Research Institute at Nationwide Children’s Hospital
Dept. of Pediatrics, College of Medicine, The Ohio State University
Columbus, Ohio 43205
MedicalResearch.com: What is the background for this study?
Response: From 2009-2014, all 50 states and the District of Columbia passed their state TBI laws, more commonly known as concussion laws, to mitigate severe consequences of concussions.
These laws often include 3 core components:
(1) mandatory removal from play following actual or suspected concussions,
(2) requirements to receive clearance to return to play from a licensed health professional, and
(3) education of coaches, parents, and athletes regarding concussion symptoms and signs.
Our study aimed to evaluate whether the laws achieve the intended impact.
MedicalResearch.com: What are the main findings?
Response: The main findings showed that:
Jenna Jerman[/caption]
Jenna Jerman
Senior Research Associate
Guttmacher Institute
New York, NY 10038
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Abortion is a critical component of public health. The objectives of this study were to assess the prevalence of abortion among population groups and changes in rates between 2008 and 2014, as well as to provide an updated estimate of the lifetime incidence of abortion.
To estimate abortion rates, we used data from the Abortion Patient Survey, the American Community Survey, and the National Survey of Family Growth; the estimate of the lifetime incidence of abortion used data from the Abortion Patient Survey. Between 2008 and 2014, the abortion rate declined 25%, from 19.4 to 14.6 per 1,000 women aged 15 to 44. Abortion rates declined among all groups of women, though declines steeper for some populations than others. The abortion rate for adolescents aged 15 to 19 years declined 46%, the largest of any group. Abortion rates declined for all racial and ethnic groups but were larger for non-white women than for non-Hispanic white women. Although the abortion rate decreased 26% for women with incomes less than 100% of the federal poverty level, this population had the highest abortion rate of all the groups examined: 36.6. If the 2014 age-specific abortion rates prevail, 24% of women in that year will have an abortion by age 45.
Dr. Laddu[/caption]
Deepika Laddu PhD
Assistant Professor
Department of Physical Therapy
College of Applied Health Sciences
The University of Illinois at Chicago
Chicago, IL 60612
MedicalResearch.com: What is the background for this study?
Response: Recent findings in population-based cohort studies on cumulative exercise dose have caused some controversy and debate showing U-shaped trends of association between physical activity and disease risk. Our objective was to better understand this association between physical activity and cardiovascular disease risk from young adulthood to middle age.
Given that engagement in physical activity is a continuously evolving behavior throughout life, this study looked at the physical activity trajectories of 3,175 black and white participants in the multicenter, community-based, longitudinal cohort CARDIA study who reported physical activity patterns over 25 years (from 1985 through 2011), and assessed the presence of coronary artery calcification, or CAC, among participants. Unique to this study is the evaluation of long-term exercise patterns from young adulthood into middle age in CARDIA participants. Based on the trajectories (or patterns of change) of physical activity over 25 years, participants were categorized into three distinct trajectory groups: trajectory group one was defined as exercising below the national guidelines (less than 150 minutes a week), group two as meeting the national guidelines for exercise (150 minutes a week), and group three as exercising three-times the national guidelines (more than 450 minutes a week).
Dr. Reck[/caption]
Martin Reck, MD, PhD
Head of the Department of Thoracic Oncology
Head of the Clinical Trial Department
Department of Thoracic Oncology at the Lung Clinic
Grosshansdorf
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: There is an urgent medical need to improve outcomes in pretreated patients with advanced non-small cell lung cancer (NSCLC), in particular those with fast progressing tumors.
The Phase 3 REVEL study, which included patients with nonsquamous and squamous forms of NSCLC, demonstrated improved overall survival (OS), progression‐free survival (PFS), and objective response rate (ORR) – independent of histology. This analysis confirmed efficacy - with improvement of ORR, PFS and OS - in poor prognosis patients with fast progressing tumors (after 9, 12 or 18 weeks) without additional toxicity or impact on Quality of Life compared to the intent-to-treat (ITT) population results of REVEL.
Dr. Buher-Kane[/caption]
Jennifer Buher Kane PhD
Assistant Professor, Department of Sociology
University of California, Irvine 92697-510
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: It’s not uncommon for new parents to relocate in search of neighborhoods with better schools, safer streets and healthier, more kid-friendly activities. But our new study found that living in such neighborhoods before a baby is born protects against the risks of poor birth outcomes.
Published online this month in SSM – Population Health, the research shows that having highly educated, wealthy neighbors reduces an expectant mother’s risk of delivering a low-weight or preterm baby – health markers that can be associated with neurodevelopmental problems, language disorders, learning disabilities and poor health later in life.
Our study is the first to look at how both the level of affluence and disadvantage — two sociologically distinct attributes of neighborhoods — affect newborn health; past studies have only explored the impact of neighborhood disadvantage. Neighborhood disadvantage signals factors such as poverty, unemployment, or underemployment. On the other hand, neighborhood affluence is thought to signal the presence of locally-based community organizations that can meet the needs of all residents – health-related and otherwise – regardless of one’s own socioeconomic resources.
Dr. Bahl[/caption]
Manisha Bahl, MD, MPH
Director, Breast Imaging Fellowship Program,
Massachusetts General Hospital
Assistant Professor of Radiology,
Harvard Medical School
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Image-guided biopsies that we perform based on suspicious findings on mammography can yield one of three pathology results: cancer, high-risk, or benign. Most high-risk breast lesions are noncancerous, but surgical excision is typically recommended because some high-risk lesions can be upgraded to cancer at surgery. Currently, there are no imaging or other features that reliably allow us to distinguish between high-risk lesions that warrant surgery from those that can be safely followed, which has led to unnecessary surgery of high-risk lesions that are not associated with cancer.
We decided to apply machine learning algorithms to help us with this challenging clinical scenario: to distinguish between high-risk lesions that warrant surgery from those that can be safely followed. Machine learning allows us to incorporate the full spectrum of diverse and complex data that we have available, such as patient risk factors and imaging features, in order to predict which high-risk lesions are likely to be upgraded to cancer and, ultimately, to help our patients make more informed decisions about surgery versus surveillance.
We developed the machine learning model with almost 700 high-risk lesions, then tested it with more than 300 high-risk lesions. Instead of surgical excision of all high-risk lesions, if those categorized with the model to be at low risk for upgrade were surveilled and the remainder were excised, then 97.4% malignancies would have been diagnosed at surgery, and 30.6% of surgeries of benign lesions could have been avoided.
Dr. Marcozzi[/caption]
David Marcozzi, MD, MHS-CL, FACEP
Associate Professor
Director of Population Health
Department of Emergency Medicine
Adjunct Associate Professor
Co-Director of the Program in Health Disparities and Population Health
Department of Epidemiology and Public Health
University of Maryland School of Medicine
Assistant Chief Medical Officer for Acute Care
University of Maryland Medical Center
MedicalResearch.com: What is the background for this study?
Response: Nearly half of all US medical care is delivered by emergency departments, according to a new study by researchers at the University of Maryland School of Medicine (UMSOM). And in recent years, the percentage of care delivered by emergency departments has grown. The study highlights what many experts argue is a major flaw in American health care: the use of emergency care in non-urgent cases, where clinics and doctor’s offices would be more appropriate.
“I was shocked by this result. This really helps us understand health care in this country. This research underscores the fact that emergency departments are critical to our nation’s healthcare delivery system, particularly for Americans who have no access to care.” said David Marcozzi, MD, MHS-CL, FACEP, an associate professor in the UMSOM Department of Emergency Medicine, and co-director of the UMSOM Program in Health Disparities and Population Health. “Patients seek care delivered in emergency departments for many reasons, and we need to face this fact this is a significant segment of healthcare and actually it may be delivering the type of care that individuals want and need—24/7, 365 days.” Although he now focuses on population health and hospital throughput, Dr. Marcozzi is an emergency room doctor himself, and works one or two days a week in the University of Maryland Medical Center emergency department, treating patients.
Christopher M. Jones, PharmD
Office of the Assistant Secretary for Planning and Evaluation
Office of the Secretary
U.S. Department of Health and Human Services
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Drug overdoses are the leading cause of injury death in the United States, resulting in approximately 52,000 deaths in 2015. Although prescription drugs, in particular opioid pain relievers, were primarily responsible for the rapid expansion of this large and growing public health crisis, illicit drugs (heroin, illicit fentanyl, cocaine, and methamphetamines) now are contributing substantially to the problem. Understanding differences in illicit drug use, illicit drug use disorders, and overall drug overdose deaths in metropolitan and nonmetropolitan areas is important for informing public health programs, interventions, and policies.
We found that the prevalence of self-reported past-month use of illicit drugs increased significantly across urban status (large metropolitan, small metropolitan, and nonmetropolitan) between 2003-2005 and 2012-2014. Prevalence was higher for males than females, however, in the large metropolitan group, the percentage increase in prevalence from 2003–2005 to 2012–2014 was greater for females (23.4%) than for males (21.6%). There were notable differences by age. During 2012–2014, respondents aged 18–25 years had the highest prevalence of past-month use of illicit drugs for all urban levels. For respondents in this age group, the prevalence increased slightly from 2003–2005 to 2012–2014 in large metropolitan areas while the prevalence remained stable among small metropolitan area respondents and nonmetropolitan area respondents. Past-month use of illicit drugs declined over the study period for the youngest respondents (aged 12–17 years), with the largest decline among small metropolitan area youth.
Ali Rowhani-Rahbar, MD, MPH, PhD
Associate Professor, Department of Epidemiology
Adjunct Associate Professor, Department of Pediatrics
University of Washington
Seattle, WA 98195
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: The impact of firearm carrying on public health and public safety is a topic of considerable interest in the US. Nonetheless, contemporary national data on some of the most fundamental questions about the scope of firearm carrying among adults in the US do not exist. We used data collected through a nationally representative survey designed by investigators at Harvard University and Northeastern University and conducted in 2015 to understand why, how frequently, or in what manner (i.e., concealed or openly) US adults carry loaded handguns on their person. We also examined the prevalence of handgun carrying among this group by the stringency of state laws regulating concealed carry permits.
Prof. Siegel[/caption]
Michael Siegel, MD, MPH
Professor, Department of Community Health Sciences
Boston University School of Public Health
Boston, MA 02118
MedicalResearch.com: What is the background for this study?
Response: A central question in the debate about public policies to reduce firearm violence is whether easier access to concealed handguns increases or decreases the rate of firearm-related homicides. Previous studies on the impact of concealed carry permitting laws have yielded inconsistent results. Most of these studies were conducted more than a decade ago. This study provided a reexamination of this research question with more recent data, up to and including the year 2015.
While all states allow certain persons to carry concealed handguns, there are 3 major variations in permitting policy. In 9 states, law enforcement officials have wide discretion over whether to issue concealed carry permits; these are referred to as “may issue” states because police chiefs can deny a permit if they deem the applicant to be at risk of committing violence, even if there is not a criminal history. In 29 states, there is little or no discretion; these are referred to as “shall-issue” states because permits must be issued if requisite criteria are met. In an additional 12 states, no permit is necessary to carry a concealed handgun.
“Headache.” by Avenue G[/caption]
Fu-Chi Yang, M.D., Ph.D.Assistant Professor
Department of Neurology,
Tri-Service General Hospital
National Defense Medical Center
Taipei, Taiwan
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Migraineurs are likely to suffer from comorbid depression and anxiety. Furthermore, increased migraine frequency is associated with an increased risk of mood/anxiety disorders. It is not distinguished by grouping frequency of migraine attacks, whether it is associated with severity scores of depression and anxiety. Thus, we evaluated the relationship between severity of depression/anxiety and migraine frequency
We mainly found that the severity of depression (BDI and HADS-depression scores) and anxiety (HADS anxiety score) were related to migraine frequency, after adjusting confounding factors.
Air Pollution, Beijing[/caption]
Philip J. Landrigan, MD, MSc, FAAP
Dean for Global Health
Professor of Preventive Medicine and Pediatrics
Arnhold Institute for Global Health
Icahn School of Medicine at Mount Sinai
MedicalResearch.com: What is the background for this study? What are the main findings?
Aparna Soni[/caption]
Aparna Soni, MA
Department of Business Economics and Public Policy
Kelley School of Business
Indiana University, Bloomington
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Cancer is the leading cause of death among the non-elderly population in the United States. Unfortunately, uninsured people are less likely to get screened for cancer, and treatment is often unaffordable for those who are uninsured.
One of the key objectives of the Affordable Care Act (ACA) was to improve outcomes for cancer patients. Our objective in this study was therefore to assess changes under the ACA in insurance coverage among patients newly diagnosed with cancer.
Our main finding is that uninsurance among patients with newly diagnosed cancer fell by one-third in 2014.
Dr. Rahimi[/caption]
Professor Kazem Rahimi, FRCP MD DM MSc FES
Deputy Director, The George Institute for Global Health UK
Associate Professor of Cardiovascular Medicine, University of Oxford
Honorary Consultant Cardiologist, Oxford University Hospitals NHS Trust
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Mitral regurgitation, the most common heart valve disorder in high-income countries, has until now been considered a degenerative disorder, which results from damage over time due to ‘wear and tear’. As a result, the focus of medical practitioners has been on treating the disorder – by repairing or replacing the valve – rather than preventing it. This is partly because there has been a lack of large-scale, longitudinal studies investigating the effect of risk factors on the condition.
We set out to analyse data on 5.5 million patients in the UK over 10 years. Our findings show, for the first time, that elevated blood pressure is an important risk factor for mitral regurgitation. Consistent with prior evidence on blood pressure associations with other cardiovascular disease - such as stroke and heart attacks – we found an association with mitral regurgitation that is continuous across the whole spectrum of blood pressure. More specifically, every 20 mmHg higher baseline systolic blood pressure is associated with a 26% increased risk of mitral regurgitation, with no threshold below or above which this relationship is not true.
The association we found was only partially mediated by conditions that are established causes of secondary mitral regurgitation, which suggests that high blood pressure has a direct and independent effect on valve degeneration.
Sheryl Cates[/caption]
Sheryl Cates
RTI International
Durham, NC
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: The goal of this research was to provide a better understanding of consumer perceptions of edible marijuana products, including why users prefer edibles relative to other forms of marijuana such as smoking and vaping and concerns regarding the consumption and questions related to, how long do edibles last? And many more! This is important as more states legalize the use of recreational marijuana products. With the increasing popularity of edibles, concerns exist that do not exist with other methods of using marijuana, such as smoking or vaping. These concerns include delayed activation time; accidental ingestion, particularly by children and older adults; and dose titration.
The study team conducted eight focus groups (four groups in Denver, Colorado, and four groups in Seattle, Washington) with users of edibles. Most participants preferred edibles to smoking marijuana because there is no smell from smoke and no secondhand smoke. Other reasons participants like edibles included convenience, discreetness, longer-lasting highs, less intense highs, and edibles’ ability to aid in relaxation, reduce anxiety, and alleviate pain more so than smoking marijuana. Concerns and dislikes about edibles included delayed effects, unexpected highs, the unpredictability of the high, and inconsistency of distribution of marijuana in the product. No participants in either location mentioned harmful health effects from consuming edibles as a concern. Although focus group findings are not generalizable, the findings are useful for helping inform policy makers and regulators as they establish regulations regarding the manufacture, labeling, and sale of edibles.
Dr. Groessl[/caption]
Erik Groessl PhD
Associate Adjunct Professor
Family Medicine and Public Health
University of California, San Diego
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Chronic low back pain (cLBP) is prevalent among military veterans, but cLBP treatment options have limited benefits and side effects. This has resulted in efforts to reduce opioid use and embrace nonpharmacological pain treatments.
Yoga has been shown to improve health outcomes and have few side effects in non-veteran community samples.
Our objective was to study the effectiveness and safety of yoga for military veterans with chronic low back pain. In a study of 150 veterans with cLBP, we found that yoga participants had greater reductions in disability and pain than those receiving usual. Opioid medication use declined among all participants, and no serious side effects occurred.
Ron Walborn Jr.[/caption]
Ron Walborn Jr.
Prebiotin CEO
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: The product Prebiotin™ Prebiotic Fiber was brought to market in 2007 by Dr. Frank Jackson, a gastroenterologist out of Harrisburg, PA. He found through 40 years of experience with his patients that a variety of digestive issues benefitted from daily supplementation with a soluble prebiotic fiber, specifically, oligofructose-enriched inulin (OEI) derived from chicory root.
In the late summer of 2012, Prebiotin caught the attention of Dr. Dominic Raj at the Internal Medicine Department of George Washington University. Dr. Raj’s laboratory showed that patients with kidney disease may have a higher level of release of endotoxins like p-Cresol sulfate and indole from the bacteria in the gut, which can move into the bloodstream and promote inflammation.
This early work was the basis of a successful grant application. Researchers were interested in investigating the therapeutic potential of altering the composition and/or function of the gut microbiome in this patient population, based on the understanding that by building up the levels of healthy bacteria in the gut, undesirable bacteria is eventually crowded out, thereby reducing the release of harmful endotoxins into the system.
Monogamous Titi monkeys[/caption]
Karen L. Bales PhD
Professor of Psychology
University of California
Davis, CA 95616
MedicalResearch.com: What is the background for this study?
Response: Titi monkeys are a socially monogamous species in which adults form pair bonds. In my laboratory we are studying the neurobiology of pair bonding, and understanding jealousy is important because it's one mechanism by which the pair bond is maintained. In this study, male titi monkeys viewed their pair mate next to a stranger male, and we examined the neural, behavioral, and hormonal consequences.
Tobias Gerstenberg, PhD
MIT
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: The question of how causation is best understood has been troubling philosophers for a long time. As psychologists, we are particularly interested in understanding how people make causal judgments.
In our experiments, we showed participants video clips of colliding billiard balls. Participants were asked to say whether one ball (ball A) caused another (ball B) to go through a gate, or prevented it from going through. We used eye-tracking technology to record participants' eye-movements as they were watching the clips.
The results showed that participants spontaneously engaged in counterfactual simulation when asked to make causal judgments. They not only looked at what actually happened, but also tried to anticipate where ball B would have gone if ball A hadn't been present. The more certain participants were that ball B would have missed the goal if ball A hadn't been there, the more they agreed that ball A caused ball B to go through the gate.
In a control condition we asked participants about what actually happened. In this condition, participants were much less likely to simulate where ball B would have gone. Together, these findings demonstrate a very close link between counterfactual simulation and causal judgment.
Dr. Wenyao Xu[/caption]
Dr. Wenyao Xu, PhD
Assistant Professor
Department of Computer Science & Engineering
University at Buffalo, the State University of New York (SUNY)
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: We try to resolve the challenge of Logging-in and logging-out tedious routine. We find it is possible to remotely "listen" to the heartbeat and recognize the user's identity by using a novel doppler radar sensor.
Aida Eslami, Ph.D.
Postdoctoral Research Fellow
Dr. Denise Daley's research group
Centre for Heart and Lung innovation
Providence Heart + Lung Institute
St. Paul's Hospital
Vancouver, BC
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Peanut allergy and food allergies in general are caused by a combination of both genetic and environmental factors. Currently, the genetic basis of peanut allergy is unclear due to a lack of studies on food related allergies.
Our study was comprised of 850 individuals with peanut allergy from the Canadian Peanut Allergy Registry (CanPAR), and nearly 1,000 individuals without peanut allergy and other food allergies. We looked at over 7.5 million genetic markers through a genome-wide association study (GWAS) to identify genes potentially associated with peanut allergy and other food allergies. Our findings are based on results from the CanPAR in combination with the results from other countries: USA, Australia, Germany and the Netherlands.
We identified a gene that is associated with both peanut allergy and other food allergies. This gene is called c11orf30/EMSY and has previously been shown to be involved in other conditions such as asthma, eczema, and allergic rhinitis.