Author Interviews, Dermatology, Medical Imaging, Melanoma / 14.04.2025
JAMA Dermatology: Autonomous Imaging System Can Deliver Reliable Total Body and Dermatoscopic Images for Skin Cancer Screening
MedicalResearch.com Interview with:
[caption id="attachment_67909" align="alignleft" width="150"]
Dr. Gibert[/caption]
Pau Rosés-Gibert, MD
Dermatology Department, Hospital Clínic Barcelona
University of Barcelona,
Fundació Clínic per la recerca biomédica, Institut d’Investigació Biomèdica August Pi i Sunyer, IDIBAPS
Diagnosis Dermatologica,
Dermavision Solutions
Barcelona, Spain and
Dermatology Department, Hospital de Figueres, Figueres, Spain
MedicalResearch.com: What is the background for this study?
Response: Skin cancer monitoring, particularly in high-risk patients with atypical mole syndrome, traditionally relies on total body photography (TBP) combined with digital dermoscopy. This approach, though effective, is slow, labor-intensive, and prone to oversight since clinicians must manually locate and image individual lesions. Recent improvements in automated imaging systems, lighting, and dermoscopy software have raised the potential for fully autonomous systems to streamline this process — leading to the development of the autonomous total body photographic and dermoscopic device tested in this study.
Dr. Gibert[/caption]
Pau Rosés-Gibert, MD
Dermatology Department, Hospital Clínic Barcelona
University of Barcelona,
Fundació Clínic per la recerca biomédica, Institut d’Investigació Biomèdica August Pi i Sunyer, IDIBAPS
Diagnosis Dermatologica,
Dermavision Solutions
Barcelona, Spain and
Dermatology Department, Hospital de Figueres, Figueres, Spain
MedicalResearch.com: What is the background for this study?
Response: Skin cancer monitoring, particularly in high-risk patients with atypical mole syndrome, traditionally relies on total body photography (TBP) combined with digital dermoscopy. This approach, though effective, is slow, labor-intensive, and prone to oversight since clinicians must manually locate and image individual lesions. Recent improvements in automated imaging systems, lighting, and dermoscopy software have raised the potential for fully autonomous systems to streamline this process — leading to the development of the autonomous total body photographic and dermoscopic device tested in this study.
Dr. Sundar[/caption]
Dr. Mzoughi[/caption]
Slim Mzoughi, PhD
Dr. Yu Mengge[/caption]
Dr Yu Mengge
Research Fellow, Cancer & Stem Cell Biology Signature Research Programme
Duke-NUS Medical School
MedicalResearch.com: What is the background for this study?
Response: The background of this study is rooted in the observation that certain genetic variations among East Asian populations, notably the BIM deletion polymorphism (BDP), impact treatment outcomes in chronic myeloid leukaemia (CML).
Patients with the BDP show resistance to conventional treatments, specifically tyrosine kinase inhibitors like imatinib. This resistance stems from the variant's role in promoting cancer cell survival, which leads to more aggressive disease progression.