Dr. Sally Lau[/caption]
Dr. Sally Lau MD
Medical oncologist, NYU Langone’s Perlmutter Cancer Center
Assistant professor of medicine
NYU Grossman School of Medicine
MedicalResearch.com: How big is the problem of lung cancer?
Response: Amongst all cancer types, lung cancer is the number 1 killer in the US.
Response: We started many years ago by studying some natural and synthetic molecules that were able to counteract the early stages of this disease. With a view to early prevention, we wondered if these molecules could be routinely taken with the diet or dietary supplements. So our studies focused on the search for bioactive molecules present in food and edible plants.
Hops are very rich in polyphenolic compounds, and for this reason it is historically used for the production of beer, but also for the preparation of herbal teas and infusions, and its uses in traditional medicine are known. In recent years we have also collected interesting results on Coffee, Sage, Radix Imperatoriae, Cocoa and Cinnamon extracts.
Dr. Dhingra[/caption]
Lovedeep Singh Dhingra, MBBS
Postdoctoral Research Associate
Cardiovascular Data Science (CarDS) Lab
Yale School of Medicine
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Wearable devices are shown to have multiple health-related features, including heart rate and activity monitoring, ECG tracing, and blood pressure monitoring.
In our analyses of the nationally-representative Health Information National Trends Survey (HINTS), we discovered that patients with and at risk of cardiovascular disease are less likely to use wearables. Older patients, patients with lower education, and patients with lower incomes are less likely to use wearables. Also, among adults with access to wearables, patients with cardiovascular disease use their devices less frequently as compared to the overall population.
Dr. Stevermer[/caption]
James Stevermer, M.D., M.S.P.H.
Vice chair for clinical affairs
Professor of family and community medicine
University of Missouri
Medical director of MU Health Care Family Medicine–Callaway Physicians,
Dr. Stevermer joined the U.S. Preventive Service Task Force in January 2021.
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: As people get older, they are more at risk for many chronic conditions like heart disease, osteoporosis, cancer, and diabetes. It’s unclear how much menopause—which typically occurs around age 50—contributes to this risk. Although we all want to stay healthy as we age, the Task Force does not recommend that people who have already gone through menopause use hormone therapy to prevent chronic health problems.
Dr. Dai[/caption]
Dr. Hongying Daisy Dai, PhD
Professor and Associate Dean of Research
The College of Public Health
University of Nebraska Medical Center.
MedicalResearch.com: What is the background for this study?
Response: Tobacco use landscape has been changing in the United States with fewer combustible cigarette smokers and more e-cigarette and other emerging tobacco users. Nicotine concentration level is a key product characteristic of modern e-cigarette products and high-nicotine vaping devices have recently become available. This study seeks to examine whether biomarkers of exposure to tobacco-related toxicants have changed since 2013 among adult nicotine e-cigarette users, non-nicotine e-cigarette users, and cigarette smokers.
Dr. Shan[/caption]
Zhilei Shan, MD, PhD
Postdoctoral fellow on Nutritional Epidemiology
Harvard T.H. Chan School of Public Health
MedicalResearch.com: What is the background for this study?
Response: Unhealthy sleep behaviors and sleep disturbances are associated with higher risk of multiple diseases and mortality. The current profiles of sleep habits and disturbances, particularly the differences between workdays and free days, are unknown in the contemporary US.
MedicalResearch.com: What are the main findings?
Response: In this nationally representative cross-sectional analysis with 9004 adults aged 20 years or older, differences in sleep patterns between workdays and free days were observed. The mean sleep duration was 7.59 hours on workdays and 8.24 hours on free days (difference, 0.65 hour). The mean sleep and wake times were at 11:02 PM and 6:41 AM, respectively, on workdays and 11:25 PM and 7:41 AM, respectively, on free days (differences, 0.23 hour for sleep time and 1.00 hour for wake time). With regard to sleep disturbances, 30.5% of adults experienced 1 hour or more of sleep debt,46.5% experienced 1 hour or more of social jet lag, 29.8% had trouble sleeping, and 27.2% experienced daytime sleepiness.
Dr. Batres[/caption]
Carlota Batres, Ph.D.Assistant Professor, Department of PsychologyDirector, Preferences Lab
PreferencesLab.comFranklin and Marshall College
MedicalResearch.com: What is the background for this study?
Response: Makeup is commonly attributed with increasing attractiveness in female faces, but this effect has not been investigated in male faces.
We therefore sought to examine whether the positive effect of makeup on attractiveness can be extended to male faces.
Sean M Hughes MA
Department of Obstetrics and Gynecology
University of Washington
Seattle, WA
MedicalResearch.com: What is the background for this study?
Response: Young women are at elevated risk of getting sexually transmitted infections at the age when they typically start to have sexual intercourse. It’s not known whether this elevated risk is a consequence of behavioral factors (such as choices around use of barrier protection), physiological factors (such as a difference in the immune system) or a combination of both. In this study, we investigated a physiological factor: the immune system in the vagina.
Good mental health means you are more likely to take control of your day. Whether you have an early shift or a long one, with a more positive mindset, you are sure to show up and get the work done to the best of your ability.
It also means that those that choose their shifts (such as locum pharmacists, GPs, or nurses) will take on more work because they feel like they can manage it. So if you’re a locum healthcare worker, even using a shift-scheduling platform such as Workflare can help you gain more control over your day and, in turn, feel less stressed.
Dr. Egemen[/caption]
Dr. Didem Egemen PhD
Statistician, Division of Cancer Epidemiology & Genetics
National Cancer Institute
MedicalResearch.com: What is the background for this study?
Response: Persistent infection with human papillomavirus (HPV), a sexually transmitted disease, is the cause of virtually all cervical cancers. Various studies have reported high effectiveness of HPV vaccination in preventing HPV infection and cervical cancer, particularly when administered at early ages.
In this study, we looked at the proportion of females eligible for vaccination (<26 years of age in 2006 when the vaccine was FDA approved) who were unvaccinated, vaccinated against HPV before sexual debut, and vaccinated after debut. Then we estimated the prevalence of HPV 16 and 18, the two HPV genotypes that cause most cervical cancers, in each subset.
Dr. van der Velde[/caption]
Jeroen van der Velde, PhD
Leiden University Medical Center
Dept. Clinical Epidemiology, C7-102
Leiden, The Netherlands
MedicalResearch.com: What is the background for this study?
Response: We hypothesized that, in addition to the amount of physical activity, the pattern in which physical activity is accumulated over the day is relevant for metabolic health.
Several studies previously showed beneficial effects of interrupting sedentary periods with short periods of activity (breaks in sedentary time) on glucose control. In addition, very recently it has been argued that the timing of physical activity during the day may be relevant for metabolic health. This was mainly shown in animal studies and intervention studies with supervised high intensity exercise training in men with impaired glucose control or type 2 diabetes. If timing of physical activity matters in a ‘free-living’ setting in the general population is largely unknown.
Therefore, our aim was to investigate associations of timing of physical activity and breaks in sedentary time with liver fat content and insulin resistance in a middle-aged population.
Caring for somebody with dementia can quickly begin to take over your life. But as much as you love your loved one, it’s important to take time for yourself too....
Dr. Kubik[/caption]
Martha Kubik, Ph.D., R.N.
Professor, School of Nursing
College of Health and Human Services
George Mason University
Member, U.S. Preventive Services Task Force
MedicalResearch.com: What is the background for this study?
Response: Too many children and teens in the United States experience mental health conditions including anxiety, depression, and suicidal thoughts or behaviors. There is a critical need to address the mental health of children and adolescents in primary care so that they can get the support they need to thrive.
Tooth discoloration is such a common issue. It can be caused by improper brushing habits, smoking, or even drinking too many dark beverages like coffee or tea. So, people often opt for teeth whitening as a resolution.
Teeth whitening isn’t the only solution for tooth discoloration. Dental veneers, which are little shells that get placed over the teeth, can cover up yellowed teeth or teeth with brown spots quite effortlessly. This way, you won’t have to worry about regularly getting your teeth bleached or purchasing expensive teeth-whitening products.
Dr. Prerau[/caption]
Michael J. Prerau, Ph.D.
Assistant Professor of Medicine,
Faculty, Division of Sleep Medicine
Harvard Medical School
Associate Neuroscientist and
Director of the Neurophysiological Signal Processing Core
Division of Sleep and Circadian Disorders
Department of Medicine Brigham and Women's Hospital
MedicalResearch.com: What is the background for this study?
Response: The brain is highly active during sleep, which makes it an important, natural way to study neurological health and disease. Scientists typically study brain activity during sleep using the electroencephalogram, or EEG, which measures brainwaves at the scalp. Starting in the mid 1930s, the sleep EEG was first studied by looking at the traces of brainwaves drawn on a paper tape by a machine. Many important features of sleep are still based on what people almost a century ago could most easily observe in the complex waveform traces. Even the latest machine learning and signal processing algorithms for detecting sleep waveforms are judged against their ability to recreate human observation.
In this study, the researchers asked: What can we learn if we expand our notion of sleep brainwaves beyond what was historically easy to identify by eye?
Compassion fatigue is when you are exposed to suffering, trauma, or similar negative emotional states in others so much that you become desensitized and indifferent to it. You may also hear it referred to as secondary trauma or vicarious trauma, with many arguing that it’s an inevitable response.
Whichever name you use, it’s a condition in which you feel physically and psychologically exhausted, resulting in a diminished capacity for empathy. This, in turn, has a negative impact on your ability to do your job as a nurse.
Sadly, compassion fatigue is not uncommon in the healthcare field, which is why it’s so important to be alert to the symptoms and understand how to respond when they arise.
Royce Zhou[/caption]
Royce Zhou, MD/PhD Candidate
Icahn School of Medicine at Mount Sinai
MedicalResearch.com: What is the background for this study?
Response: The background of this story is to see whether things outside of the cancer cell, such as the tumor microenvironment, can lead to epigenetic changes within the cancer cell. These changes are largely believed to be due to factors inside the cell, not outside.
Super-enhancers are the top 1-2% of enhancers in the genome. They control cell identity genes and oncogenes in cancer.
Dr. White[/caption]
Alexandra J. White, PhD, MSPH
Stadtman Investigator
Epidemiology Branch
National Institute of Environmental Health Sciences
National Institutes of Health
Research Triangle Park, NC
MedicalResearch.com: What is the background for this study? What is the chemical primarily used in hair straighteners?
Response: Hair products such as dye and chemical straighteners contain several different chemicals that may act as carcinogens or endocrine disruptors and thus may be important for cancer risk. Straighteners in particular have been found to include chemicals such as phthalates, parabens, cyclosiloxanes and metals and may release formaldehyde when heated. Previous research has suggested that hair dye and chemical straighteners are related to other hormone-sensitive cancers such as breast and ovarian cancer, but no previous study has considered how they are related to uterine cancer risk.
Dr. Wong[/caption]
Mitchell Wong, MD PhD
Professor of Medicine
Executive Vice Chair for Research Training
Department of Medicine
Executive Co-Director, Specialty Training and Advanced Research (STAR) Program
Director, UCLA CTSI KL2 Program
UCLA Division of General Internal Medicine and Health Services Research Los Angeles, CA 90024
MedicalResearch.com: What is the background for this study?
Response: It is estimated that social factors like poverty, education, and housing have a large impact on health. Yet, there are few interventions that exist to directly address those issues. Schools are a promising solution since society already invests heavily in education and schools are an everyday part of most children’s lives.
Dr. Carrero[/caption]
Juan Jesus Carrero Pharm PhD
Professor of Epidemiology
Cardio-renal Department of Medical Epidemiology and Biostatistics
Karolinska Institutet, Stockholm
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Concerns on the possibility of (direct oral anticoagulants) DOAC-related nephropathy may limit its use.
In this cohort study of non-valvular AF patients from routine clinical practice, initiation of DOAC vs (vitamin K antagonists) VKA was associated with more favorable kidney outcomes, i.e., a lower risk of the composite of kidney failure and sustained 30% eGFR decline, as well as a lower risk of AKI occurrence.
In agreement with trial evidence, we also showed that DOAC vs VKA treatment was associated with a lower risk of major bleeding, but a similar risk of the composite of stroke, systemic embolism or death.
One example of Dermatomyositis: DermNet image[/caption]
Response: Dermatomyositis is a rare autoimmune inflammatory disease that affects muscles and skin, although muscular forms without skin symptoms and vice versa are also seen. The exact etiology of the disease is not known but is thought to be immune-mediated with many patients having highly specific autoantibodies. There is no cure for dermatomyositis, but several types of treatment have been successfully used in the last years including different kinds of immunosuppressants (e.g. steroids) and intravenous immune globulins (IVIG) to improve the patient’s condition. So far, none of these treatments was approved for use in dermatomyositis based on large, randomized, placebo-controlled trials. Their effectiveness was mainly deduced from clinical experience and from small clinical trials. The ProDERM study was the first large, pivotal, randomized placebo-controlled trial to evaluate the efficacy and safety of intravenous immune globulin (IVIG) in dermatomyositis patients.
Dr. Ogedegbe[/caption]
Gbenga Ogedegbe, MD, MPH
Dr. Adolph & Margaret Berger Professor of Population Health
Director, Division of Health & Behavior
Director Center for Healthful Behavior Change
Department of Population Health
NYU Langone Health
NYU School of Medicine
Member of the U.S. Preventive Services Task Force
MedicalResearch.com: What is the background for this study?
Response: Syphilis has become more common over the past 20 years, after reaching a record low in 2000. The Task Force found that screening people who are at increased risk for syphilis can identify the infection early so it can be treated before problems develop. For that reason, the Task Force recommends screening people who are at increased risk for syphilis infection.
Healthcare is one of the largest industries in the country, and it is also outpacing other industries in terms of job growth. Understanding which non-clinical and non-medical options are on the rise the most is how hospitals can advertise and improve recruitment in roles they desperately need. Non-clinical roles typically require...