Author Interviews, Brigham & Women's - Harvard, Kidney Disease, Stem Cells / 20.11.2016
Kidney Organoids Derived from Human Pluripotent Stem Cells Model Polycystic Disease
MedicalResearch.com Interview with:
Dr. Ryuji Morizane MD, PhD
Associate Biologist, Renal Division
Brigham and Women’s Hospital
Affiliated Faculty, Harvard Stem Cell Institute
Instructor, Harvard Medical School
MedicalResearch.com: What is the background for this study?
Response: Polycystic kidney disease (PKD) accounts for 10% of end-stage kidney disease (ESKD), and there is currently no curable treatment available for patients with PKD.
The adult onset form of PKD, the most common type of PKD, takes 30 years to form cysts in humans; therefore, it is difficult to study mechanisms of PKD to find novel therapeutics for patients.
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