Author Interviews, Orthopedics, Pediatrics, PT-Rehabilitation / 20.10.2025

[caption id="attachment_71041" align="alignleft" width="200"]chris-church Chris Church[/caption] MedicalResearch.com Interview with: Chris Church MPT Director, Gait & Motion Analysis Laboratory Nemours duPont Hospital for Children MedicalResearch.com: What is the background for this study? Would you briefly describe the condition of clubfoot and arthrogryposis? Response: Clubfoot is a congenital foot deformity in which the child is born with their foot (or feet) are stiff and in position with the foot pointing down (equinus) and in (inverted).  Idiopathic clubfoot is a condition in which these children only have issues with their feet.  Arthrogryposis is a condition in which children have contractures in multiple parts of their body.  Children with Arthrogryposis often have clubfeet that are tighter and more difficult to treat than the more common idiopathic type. Idiopathic clubfoot is effectively corrected with a conservative treatment known as the Ponseti method. Recent studies have shown successful short-term correction using Ponseti treatment in the stiffer clubfoot associated with arthrogryposis, but there are few studies analyzing long-term results. This study compares outcomes of the Ponseti method in 10-year-old children with idiopathic clubfoot and clubfoot associated with arthrogryposis. MedicalResearch.com: Would you describe the Ponseti method? Does it require specialized or complicated training to implement treatment? Response: Clubfoot was treated with surgery in the past.  Now we use a more conservative treatment that is provided by pediatric orthopedic surgeons and physical therapists.  The Ponseti method involved serial casting in infancy, Achillies tenotomies, and prolonged use of bracing during sleep until age 5 years. [caption id="attachment_71050" align="alignleft" width="300"]ClubfootNemours Image Clubfoot
Nemours Image[/caption] [caption id="attachment_71051" align="alignleft" width="300"]Clubfoot Nemours Image Clubfoot
Nemours Image[/caption]            
Author Interviews, Diabetes, Kidney Disease, NYU/NYMC, Weight Research / 20.10.2025

MedicalResearch.com Interview with: [caption id="attachment_71025" align="alignleft" width="225"]Michael A. Weintraub, MDClinical Assistant Professor Department of Medicine NYU Grossman School of Medicine Dr. Weintraub[/caption] Michael A. Weintraub, MD Clinical Assistant Professor Department of Medicine NYU Grossman School of Medicine MedicalResearch.com: What is the background for this study? Response: The study addresses a critical knowledge gap in diabetes management for dialysis patients. Of the 808,000 people on dialysis in the United States, approximately 60% have diabetes and would be eligible for GLP-1 receptor agonists (GLP-1 RAs). However, these medications have not been well-studied in this population because dialysis dependence is frequently an exclusion criterion in clinical trials.
Plastic Surgery, Surgical Research / 14.10.2025

Top Ways Plastic Surgery Enhances Health and Well-Being

Key Takeaways

  • Plastic surgery offers significant benefits for both physical health and mental well-being.
  • Addressing functional concerns can lead to a higher quality of life and improved self-image.
  • Working with Board-certified plastic surgeons ensures safety and personalized care.
  • Procedures can serve as motivation and support for maintaining healthier habits long term.
 

Table of Contents

  1. Introduction
  2. Enhancing Physical Functionality
  3. Boosting Self-Confidence and Mental Health
  4. Alleviating Chronic Pain
  5. Encouraging a Healthier Lifestyle
  6. Reducing Risk of Cardiovascular Issues
  7. Improving Vision
  8. Conclusion
Author Interviews / 14.10.2025

Modern Vision Correction Trends

Key Takeaways

  • Artificial intelligence is boosting precision and safety for LASIK surgery.
  • Non-invasive technologies like PiXL give more patients the option for vision correction without traditional surgery.
  • Laser-free alternatives, such as electromechanical reshaping, are expanding choices for those hesitant about surgery.
  • Smart glasses are leveraging technology to improve the quality of life for people with low or impaired vision.
LASIK

Table of Contents

  • Introduction
  • AI-Enhanced LASIK Procedures
  • Non-Invasive PiXL Technology
  • Electromechanical Reshaping: A Laser-Free Alternative
  • Smart Glasses: Merging Technology with Vision Correction
  • Conclusion
Author Interviews, Cancer Research, Dental Research, JAMA, Microbiome, NYU/NYMC, Pancreatic / 13.10.2025

[caption id="attachment_70956" align="alignleft" width="125"]Jiyoung Ahn, PhDProfessor of Population Health, NYU Grossman School of Medicine Associate Director for Population Science, NYU Perlmutter Cancer Center  NYU Langone Health New York, NY 10016 Dr. Jiyoung Ahn[/caption] MedicalResearch.com Interview with: Jiyoung Ahn, PhD Professor of Population Health, NYU Grossman School of Medicine Associate Director for Population Science, NYU Perlmutter Cancer Center NYU Langone Health New York, NY 10016 MedicalResearch.com: What is the background for this study? Response: About 10 years ago. we reported that people with poor oral health seem to have a greater risk of pancreatic cancer development.  We suspected that this could be due to oral microbiota.  More recently, animal studies, by other groups, showed that bacteria from the mouth can actually travel through saliva into the pancreas. But we didn’t know which exact species of bacteria or fungi might be involved in pancreas cancer development. We therefore conducted this large human study to examine the oral microbiome — including whole bacteria and fungi profiles in the mouth, and to see which bacteria and fungal taxa are associated with subsequent risk of pancreatic cancer development.
Author Interviews, Dermatology, Hair Care, JAMA / 11.10.2025

[caption id="attachment_70946" align="alignleft" width="200"]dr-brett-king Dr. King[/caption] Brett King, MD, PHD  Dr. King was named an American Academy of Dermatology (AAD) “Patient Care Hero” for his work treating patients with severe alopecia areata Dermatology Physicians of Connecticut Fairfield, Connecticut MedicalResearch.com: What is the background for this study? Would you briefly explain the condition of Alopecia Areata? Response: Alopecia Areata (AA), an autoimmune form of hair loss, is common and its treatment has been revolutionized in the past ~3 years with approvals of 3 JAK inhibitors, bariticinib, ritlecitinib and deuruxolitinib. Prior to these approvals, off label treatments included the JAK inhibitors tofacitinib and ruxolitinib.   In a world of multiple treatments, especially when those treatments belong to the same medicine class, the question arises “If patients do not achieve treatment success with one medicine, might they achieve treatment success with another one?”
Author Interviews, Autism, Brigham & Women's - Harvard, JAMA / 06.10.2025

Memantine to Treat Social Impairment in Youths With ASD

MedicalResearch.com Interview with: [caption id="attachment_70898" align="alignleft" width="143"]Gagan Joshi, MDDirector, The Alan & Lorraine Bressler Clinical and Research Program for Autism Spectrum Disorder Associate Director, The Pediatric Psychopharmacology Research Program Associate Program Director, MGH Fellowship in Autism Spectrum Disorder Rovee Endowed Chair in Child Psychiatry Massachusetts General Hospital Associate Professor of Psychiatry Harvard Medical School Dr. Joshi[/caption] Gagan Joshi, MD Director, The Alan & Lorraine Bressler Clinical and Research Program for Autism Spectrum Disorder Associate Director, The Pediatric Psychopharmacology Research Program Associate Program Director, MGH Fellowship in Autism Spectrum Disorder Rovee Endowed Chair in Child Psychiatry Massachusetts General Hospital Associate Professor of Psychiatry Harvard Medical School MedicalResearch.com: What is the background for this study? Response: Intellectually capable individuals with autism often face significant challenges in social functioning, yet pharmacologic treatments specifically targeting social impairments are lacking. Our prior neuroimaging research identified abnormally elevated brain glutamate levels in intellectually capable youth with autism, suggesting a potential neurochemical pathway underlying social difficulties. Based on these findings, we examined the effects of memantine—a glutamate-modulating medication—for the treatment of autism.
Author Interviews, Cancer Research / 24.09.2025

[caption id="attachment_70763" align="aligncenter" width="500"]next-gen-cancer-sequencing Freepix image[/caption] Cancer is one of the most complex and heterogeneous diseases known to medicine. Tumors can differ not only between patients but also within a single individual, with subclones evolving over time and influencing how the disease progresses or responds to treatment. Next-generation sequencing (NGS) has become a critical tool in oncology, helping researchers and clinicians unravel this complexity at the molecular level. By analyzing DNA and RNA at high resolution, NGS enables the detection of mutations, copy number changes, gene fusions, and expression patterns that shape tumor biology. This information provides insight into cancer drivers, mechanisms of resistance, and therapeutic targets. Importantly, it also supports precision medical oncology, where treatments are guided by the specific molecular features of a patient’s tumor rather than by one-size-fits-all approaches.
Author Interviews, Blood Pressure - Hypertension, Cancer Research, Stanford / 23.09.2025

MedicalResearch.com Interview with: [caption id="attachment_70752" align="alignleft" width="150"]Minji Jung PharmD, PhDPostdoctoral Research Fellow in Epidemiology Department of Urology Stanford University Medical Center Stanford, CA Dr. Minji Jung[/caption] Minji Jung PharmD, PhD Postdoctoral Research Fellow in Epidemiology Department of Urology Stanford University Medical Center Stanford, CA MedicalResearch.com: What is the background for this study? Response: Hypertension is a well-established risk factor for kidney cancer, and previous studies have suggested potential links between antihypertensive medications and kidney cancer risk. However, distinguishing the effects of the medications from those of hypertension itself has been challenging. Our meta-analysis systematically evaluated different classes of antihypertensive drugs while accounting for hypertension.
Author Interviews, Autism, OBGYNE, Pain Research, Pediatrics / 23.09.2025

[caption id="attachment_70749" align="alignleft" width="150"]Statement from Andrea Baccarelli, MD, PhDDean of the Faculty Professor of Environmental Health Harvard T.H. Chan School of Public Health Dr. Baccarelli[/caption] Statement from Andrea Baccarelli, MD, PhD Dean of the Faculty Professor of Environmental Health Harvard T.H. Chan School of Public Health Colleagues and I recently conducted a rigorous review, funded by a grant from the National Institutes of Health (NIH), of the potential risks of acetaminophen use during pregnancy. We reviewed 46 previously published human studies worldwide. We found evidence of an association between exposure to acetaminophen during pregnancy and increased incidence of neurodevelopmental disorders in children. This association is strongest when acetaminophen is taken for four weeks or longer.
Aging, Author Interviews, Exercise - Fitness / 17.09.2025

World Cup’s Quest to Delay Aging Longevity science has a long history, dating back to the 1900s when people practiced gerontology, the scientific study of aging. In this era, scientists embarked on a study of the mortality and aging patterns in different organisms. Through the 20th century and early 21st century, aging research evolved into what we now know as longevity science, a science that goes beyond extending lifespan. Longevity science stands out for its specific focus on extending healthspan – the period of life we spend in good health. This branch of science has birthed various interventions to help us in the race against time. These include caloric restriction, genetic research, and biomarker-driven personalized medicine. And now, with the recent launch of the Longevity World Cup, Adam Ficsor is fueling the discovery of even more techniques to reverse aging.
Aging, Author Interviews / 16.09.2025

[caption id="attachment_70701" align="aligncenter" width="500"]opportunities-aging-population Photo by Kampus Production[/caption]

Introduction

For healthcare and business leaders alike, the most powerful force shaping the 21st century may not be artificial intelligence or globalization, but aging populations. Since 1950, global life expectancy has risen by nearly 20 years, a monumental shift that is redefining consumer demand, workforce structures, and health systems. By 2050, one in six people worldwide will be over the age of 65, compared with just one in eleven in 2019 (United Nations, 2019). This demographic transformation is often framed as a looming burden—pressuring pension systems, overwhelming hospitals, and shrinking workforces. But this lens ignores a fundamental reality: aging societies also represent one of the largest hidden growth opportunities in healthcare innovation. The challenge is not the demographic trend itself, but how we adapt. For forward-looking companies, investors, and policymakers, reframing aging as a platform for innovation is a strategic imperative.
Author Interviews, Cannabis, Diabetes / 16.09.2025

[caption id="attachment_70686" align="alignleft" width="150"]Ibrahim Kamel, MD, MHABoston Medical Center – Brighton Clinical Instructor Boston Medical Center Boston University Dr. Kamel[/caption] MedicalResearch.com Interview with: Ibrahim Kamel, MD, MHA Boston Medical Center – Brighton Clinical Instructor Boston Medical Center Boston University   MedicalResearch.com: What is the background for this study? Response: Cannabis use carries risk for developing Type 2 diabetes.  It is important for physicians to screen for the use of cannabis to better understand each patients risk. MedicalResearch.com: What are the main findings? Response:  Clinically physicians should screen for and council on the risk of cannabis use. People should know what is the risk in the substances they use and make the choice that they feel is right. 
Author Interviews, Laboratories / 15.09.2025

[caption id="attachment_70677" align="aligncenter" width="500"]lab-safety-protocols Photo by Artem Podrez[/caption] Medical research labs are environments where innovation and discovery thrive. However, they also involve risks that can compromise the safety of researchers and the integrity of experiments if not properly managed. Implementing essential safety practices is not optional; it is a cornerstone of responsible research. Below, we outline key measures every medical research lab should consistently carry out.

Conduct Comprehensive Risk Assessments

Every lab should start by identifying potential hazards associated with their experiments. Risk assessments involve evaluating chemical, biological, and physical hazards and determining the appropriate safety measures to mitigate them. Regularly updating these assessments ensures that new procedures or equipment do not introduce unforeseen dangers. This proactive approach can prevent accidents before they occur and foster a culture of safety among staff.

Maintain Rigorous Equipment Standards

Properly functioning equipment is critical for both safety and accuracy in research. Medical research labs should establish strict maintenance schedules and ensure all instruments meet regulatory standards. Using reliable lab equipment reduces the likelihood of malfunctions that could lead to exposure to hazardous substances or flawed experimental results. Additionally, proper training on the use of equipment helps prevent human error and ensures experiments are conducted safely and efficiently.
Author Interviews, Dental Research / 15.09.2025

Editor's note: There is considerable controversy regarding the potential risks versus benefits of toothpaste ingredients, including fluoride.  Please consult your dental and/or health care provider regarding the oral hygiene products for your needs. [caption id="attachment_70672" align="aligncenter" width="500"]holistic-vs-regular-toothpaste Source[/caption]

Introduction

Oral hygiene is a central part of overall well-being. Brushing twice a day is a habit most people follow, but what often gets overlooked is the choice of toothpaste itself. Many households reach for the standard tube found in supermarkets, while others prefer alternatives made with natural ingredients. The debate between organic toothpastes derived from plant-based or eco-friendly sources and conventional options continues to grow. Understanding the differences between these two choices is essential for making an informed decision about what is best for your dental health. Beyond cavity prevention, the type of toothpaste you use can also influence gum sensitivity, enamel strength, and even your overall brushing experience.
Allergies, Author Interviews, Pediatrics / 11.09.2025

MedicalResearch.com Interview with: [caption id="attachment_70637" align="alignleft" width="133"]Thomas B. Casale, M.D.Professor of Medicine and Pediatrics Chief of Clinical and Translational Research Division of Allergy and Immunology USF Health Morsani College of Medicine University of South Florida Tampa, Florida Dr. Casale[/caption] Thomas B. Casale, M.D. Professor of Medicine and Pediatrics Chief of Clinical and Translational Research Division of Allergy and Immunology USF Health Morsani College of Medicine University of South Florida Tampa, Florida MedicalResearch.com: What is the background for this study? Response: The data leading to FDA approval of neffy came from extensive pharmacokinetic and pharmacodynamic studies. As with previous epinephrine delivery devices, the FDA asked for data showing that after delivery of neffy the epinephrine blood levels and expected changes in pulse and blood pressure were similar to those achieved with injectable formulations of epinephrine. neffy performed as expected with blood levels of epinephrine bracketed by those achieved with EpiPen and a needle and syringe along with increases in pulse and blood pressure compatible with the epinephrine levels measured. Additionally, clinicians are interested in whether neffy would perform similarly in real clinical situations. The data from the neffy experience program provides real-world assurance that neffy can effectively treat acute allergic reactions. Given the large number of patients and the similar findings to those achieved with injectable epinephrine in previous studies, the data should provide assurance that neffy can be an effective substitute for injectable epinephrine in patients that desire a needle-free option. neffy
Author Interviews, CDC, Infections / 10.09.2025

MedicalResearch.com Interview with: CDCKristina Betz MD, PhD Measure Development and Validation Unit Lead, NHSN Surveillance Branch Division of Healthcare Quality Promotion Centers for Disease Control and Prevention (CDC) MedicalResearch.com: Would you briefly explain what is meant by sepsis? i.e., how common is it, how serious, what are the major causes? Response: Sepsis is a life-threatening medical emergency that happens when the body’s response to an infection causes vital organs to stop working properly. Sepsis is often caused by bacteria, but it can also happen because of other infections, like viruses such as COVID-19. Sepsis is one of the main reasons people go to the hospital and can be very dangerous. In the United States, about 1.7 million adults go to the hospital each year because of sepsis. Sadly, about 350,000 of these people die in the hospital or are sent to hospice care. Even if people survive sepsis, it can cause long-lasting problems. They might have new health issues, not be able to go back to work, need to go back to the hospital, or even die later on. Source: Hospital Sepsis Program Core Elements | Sepsis | CDC, What Is Sepsis | Sepsis Alliance
Author Interviews, Breast Cancer / 10.09.2025

MedicalResearch.com Interview with: [caption id="attachment_70616" align="alignleft" width="130"]Dr. Rima Patel Dr. Patel[/caption] Rima Patel, MD Assistant Professor The Tisch Cancer Institute, Division of Hematology/Oncology Icahn School of Medicine at Mount Sinai MedicalResearch.com: What is the background for this study? What are the main findings? Response: Targeted treatment options for metastatic triple negative breast cancer (TNBC) are limited. TNBCs are associated with a high frequency of PTEN loss, which can lead to activation of the mTOR pathway and tumor proliferation but may be reversible with the mTOR inhibitor everolimus. A prior phase II single arm trial of carboplatin and everolimus in patients with advanced TNBC demonstrated good tolerability and preliminary efficacy. The current study is a randomized phase II trial comparing carboplatin and everolimus with carboplatin alone in patients with metastatic TNBC. We found that the combination of carboplatin and everolimus reduced the risk of progression or death by 52%. The regimen was well tolerated and provides a promising treatment option for patients with advanced TNBC.
Author Interviews, COVID -19 Coronavirus, Pediatrics, Weight Research / 09.09.2025

MedicalResearch.com Interview with: [caption id="attachment_70576" align="alignleft" width="200"]Thao-Ly Phan, MD, MPH Medical Director, Nemours Children's Health Professor of Pediatrics Thomas Jefferson University Dr. Thao Ly Phan[/caption] Thao-Ly Phan, MD, MPH Medical Director, Nemours Children's Health Professor of Pediatrics Thomas Jefferson University MedicalResearch.com: What is the background for this study? Response: The impacts of the COVID-19 pandemic have been extensively studied in adults, but there has been limited exploration of its effects on children and adolescents. While several studies have described weight gain trends in children during the pandemic, less is known about how having a diagnosis of COVID-19 contributed to these trends. Our study drew on the NIH’s National Clinical Cohort Collaborative database, a real-world database of electronic health data from over 90 institutions across the country.  We used this dataset’s unique features to compare a diverse group of more than 11,000 children diagnosed with COVID-19 to a matched cohort of children without a diagnosis of COVID-19.
Anemia, Author Interviews, Hematology, JAMA, Pain Research, Pediatrics / 03.09.2025

MedicalResearch.com Interview with: [caption id="attachment_70522" align="alignleft" width="150"]Ibrahim Gwarzo, DrPH, MPH, MBBSResearch Scientist at Nemours Children’s Health Delaware Valley, Delaware USA Dr. Gwarzo[/caption] Ibrahim Gwarzo, DrPH, MPH, MBBS Research Scientist at Nemours Children’s Health Delaware Valley, Delaware USA MedicalResearch.com: What is the background for this study? Would you briefly explain the condition of sickle cell disease and why young people frequently present to the ER with severe pain? Response: Sickle cell disease is an inherited blood disorder that affects red blood cells. It is passed down as an autosomal recessive disorder, meaning a person must inherit the defective gene from both parents to have the disease. The condition primarily impacts hemoglobin, the protein responsible for carrying oxygen in red blood cells, which leads to changes in the shape and stability of these cells. The complications associated with the disease, including recurrent and severe pain episodes, are a direct result of these changes. These pain episodes are debilitating and unpredictable, resulting in frequent emergency department visits where they are typically treated with pain medications, including opioids. It is estimated that around 100,000 people in the United States have sickle cell disease, with about 40,000 being children. The disease has a significant prevalence in the Afro-Latino population.
Addiction, Author Interviews / 03.09.2025

[caption id="attachment_70512" align="aligncenter" width="500"]Medication-Assisted Treatment in Rural Emergency Departments Photo by Erik Mclean[/caption]

Why Medication-Assisted Treatment Matters

Opioid use disorder continues to harm communities across the United States. In 2023, more than 80,000 people died from opioid overdoses according to CDC data. Rural towns have been hit especially hard. Emergency departments in these areas are often the only place where patients can get immediate help. Medication-Assisted Treatment (MAT) is one of the most effective tools for treating opioid addiction. It combines medicines like buprenorphine or methadone with counseling. Studies show MAT reduces opioid use, lowers overdose risk, and improves long-term recovery rates. Patients who receive MAT are twice as likely to stay in treatment compared to those who do not. Emergency rooms see many patients in crisis. They are a critical access point for starting MAT. Yet, many rural hospitals still face major barriers when trying to use it.
AI and HealthCare, Author Interviews, Cannabis, Pharmacology, Technology / 28.08.2025

[caption id="attachment_70470" align="alignleft" width="150"]Duncan Dobbins, PharmD, MHIGeisinger College of Health Sciences Scranton, Pennsylvania Dr. Dobbins, PharmD[/caption] MedicalResearch.com Interview with: Duncan Dobbins, PharmD, MHI Geisinger College of Health Sciences Scranton, Pennsylvania MedicalResearch.com: What prompted this commentary, and what did you find? Response: In theory, there could be a drug interaction between immunotherapy and medical cannabis. A small (N=102) observational report from Israel appeared to find that immunotherapies worked much less well in cancer patients who also used medical cannabis.1 However, a follow up report2 took about two weeks and involved manually rechecking the math and data-analysis. Several discrepancies emerged between the methods and results. Two-tailed tests were listed in the methods yet one-tailed p values appeared in the results. Arithmetic errors, some traceable to unconventional “floor” rounding, affected key percentages. Multiple p values in Table 1 (21 out of 22) could not be reproduced with the stated tests. Finally, smoking status, a key confound, was not reported. Taken together, these issues complicate interpretation and highlight how small computational slips can cascade into larger inferential uncertainty. For this follow-up report, I was asked, “Do you think AI could have double checked this math?”
Psychological Science / 20.08.2025

emotional-intelligence This guide explains how emotional intelligence (EQ) can boost your leadership. It helps you connect with your team. It also motivates them to do their best. Let’s explore how! Do you know why some leaders earn loyalty while others find it hard to connect with their teams? Or why do some managers handle conflicts smoothly while others make things tense? The answer is emotional intelligence, also known as emotional quotient. It means understanding your own emotions and the emotions of others, and using that understanding to make better choices. It is a game-changer for leadership, team trust, and organisational success. This article uncovers eight surprising truths about emotional intelligence in leadership and highlights the trends shaping leadership in 2025 and beyond.
Author Interviews, Genetic Research, Heart Disease / 14.08.2025

MedicalResearch.com Interview with: [caption id="attachment_70301" align="alignleft" width="92"]Takeshi Tsuda, MDSenior Pediatric Cardiologist Nemours Cardiac Center Nemours Children’s Health Delaware Dr. Tsuda[/caption] Takeshi Tsuda, MD Senior Pediatric Cardiologist Nemours Cardiac Center Nemours Children’s Health Delaware MedicalResearch.com: What is the background for this study?  Would you briefly explain the condition of Duchenne Muscular Dystrophy? Response: Duchenne muscular dystrophy (DMD) is a genetic muscle disorder causing progressive muscle weakness and wasting, resulting in severe disability during childhood due to absence of dystrophin protein in the muscle cells. Cardiac disease (cardiomyopathy) also develops during early adolescence, potentially leading to heart failure. Because of its insidious progression, the onset of DMD cardiomyopathy is not clearly identified. Early treatment is essential for better outcomes, but the recognition of the preclinical stages of disease is challenging. MedicalResearch.com: Is Unrelieved Wall Stress a commonly recognized echocardiogram finding? Response: Duchenne muscular dystrophy cardiomyopathy is a unique myocardial abnormality caused by the absence of dystrophin, which serves not only as a cytoskeletal protein to maintain cellular integrity but also as a mechano-sensor to adjust wall stress to normalize myocardial oxygen demand. Dystrophin deficiency results in lack of these functions, resulting in rapid myocyte death without compensatory response to normalize wall stress. By our methods, we are able to identify the unrelieved wall stress (increase in iWS) as an early sign of DMD cardiomyopathy before visible ventricular dysfunction prevails, not by the known routine approach.
Weight Research / 07.08.2025

MedicalResearch.com Interview with: [caption id="attachment_70205" align="alignleft" width="125"]Shannon D. DonofryBehavioral Scientist B.A.Sc. in psychology/neuroscience University of Pittsburgh-Pittsburgh Campus; Ph.D, University of Pittsburgh-Pittsburgh Campus Dr. Donofry[/caption] Shannon D. Donofry Ph.D. Behavioral Scientist B.A.Sc. in psychology/neuroscience University of Pittsburgh-Pittsburgh Campus; Ph.D, University of Pittsburgh-Pittsburgh Campus   [caption id="attachment_70207" align="alignleft" width="125"]Katherine M. Rancaño, Ph.DAssociate Policy Researcher RAND Dr. Rancaño[/caption] Katherine M. Rancaño, Ph.D Associate Policy Researcher RAND   MedicalResearch.com: What is the background for this study? Response: GLP-1 medications were first used to help people with diabetes manage their blood sugar. Lately, they’ve become popular for helping people lose weight, too. Because of this, a lot more people have started using them. In our study, we asked over 8,000 adults from across the country about their use of GLP-1 medications and any side effects they had.
Author Interviews, Geriatrics, JAMA, Pharmacology / 05.08.2025

MedicalResearch.com Interview with: [caption id="attachment_70179" align="alignleft" width="220"]Emily G. McDonald MD MSc (Epi) FRCPCScientist | Research Institute of the McGill University Health Centre Associate Professor of Medicine | General Internal Medicine | McGill University Health Centre Associate Chair of Quality and Safety | Department of Medicine | McGill University Director | Canadian Medication Appropriateness and Deprescribing Network Centre for Outcomes Research and Evaluation (CORE) Montreal, QC Dr. McDonald[/caption] Emily G. McDonald MD MSc (Epi) FRCPC Scientist | Research Institute of the McGill University Health Centre Associate Professor of Medicine | General Internal Medicine | McGill University Health Centre Associate Chair of Quality and Safety | Department of Medicine | McGill University Director | Canadian Medication Appropriateness and Deprescribing Network Centre for Outcomes Research and Evaluation (CORE) Montreal, QC https://www.medsafer.org/ https://www.deprescribingnetwork.ca/   MedicalResearch.com: What is the background for this study? What are the main findings? Response: Polypharmacy (taking multiple medications) is common among older adults and can lead to serious side effects like memory problems, falls, fractures, and hospitalization. Deprescribing (the process of stopping some medications that may no longer be beneficial or where the harms outweigh the benefits) is a great solution. This study found that an electronic tool to support prescribers increased deprescribing more than 3 times compared to usual care without the software support.
Addiction, addiction-treatment, Author Interviews / 27.07.2025

MedicalResearch.com Interview with: [caption id="attachment_70015" align="alignleft" width="152"]Prof. Yonatan M. Kupchik PhD andLiran Levi, PhD student Faculty of Medicine at Hebrew University Prof. Kupchik[/caption] Prof. Yonatan M. Kupchik PhD and [caption id="attachment_70017" align="alignleft" width="138"]Liran Levi L. Levi[/caption] Liran Levi, PhD student Faculty of Medicine at Hebrew University MedicalResearch.com: What is the background for this study? Response: Motivated behavior is driven by a group of brain regions called collectively the reward system. This neural system is at the heart of every decision we make about our actions - it integrates information about the world and decides whether to perform a behavior or not based on the predicted reward/benefit. The key molecule in this process is dopamine - whenever we perform a behavior that provides a reward dopamine is released in the reward system and reinforces this behavior. Drugs of abuse exploit this system - they cause abnormally high levels of dopamine, and thus force the reward system to seek drugs constantly, even after prolonged withdrawal. From a neurobiological perspective, that is how we view substance dependence - the reward system drives people to seek for the reward.
Aging, Exercise - Fitness / 25.07.2025

MedicalResearch.com Interview with: [caption id="attachment_69623" align="alignleft" width="180"]Ding Ding (Melody), Ph.D., MPHProfessor of Public Health/NHMRC Emerging Leader Fellow Prevention Research Collaboration Sydney School of Public Health Faculty of Medicine and Health The University of Sydney Prof. Ding[/caption] Ding Ding (Melody), Ph.D., MPH Professor of Public Health/NHMRC Emerging Leader Fellow Prevention Research Collaboration Sydney School of Public Health Faculty of Medicine and Health The University of Sydney MedicalResearch.com: What is the background for this study? Response: While we already know physical activity benefits health, public guidelines focus on total minutes of moderate-to-vigorous activity per week, usually 150 to 300 minutes. However, many people track their activity by steps, a simple and accessible metric, but the popular 10,000-steps-a-day goal isn’t actually based on solid evidence. Our review sought to clarify how many steps per day are linked to meaningful health benefits.